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https://observatorio.fm.usp.br/handle/OPI/7739
Title: | Multifunctional Roles of Reticular Fibroblastic Cells: More Than Meets the Eye? |
Authors: | ALVARENGA, H. G.; MARTI, L. |
Citation: | JOURNAL OF IMMUNOLOGY RESEARCH, article ID 402038, 10p, 2014 |
Abstract: | Fibroblastic reticular cells (FRCs) are stromal cells found in secondary lymphoid organ. Despite its structural function in the lymph nodes being well established, recent studies indicate that the FRCs also play a key role in immunological processes, associated with cell transit, immune response, and cells activation quality, and contribute to peripheral tolerance. To this end, we focus this review on lymph nodes FRC characterization and discuss functional aspects such as production of cytokines and chemokines and their involvement in the immune response, seeking to establish whether certain subsets have a more functional specialization. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/Outros |
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File | Description | Size | Format | |
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art_ALVARENGA_Multifunctional_Roles_of_Reticular_Fibroblastic_Cells_More_Than_2014.PDF | publishedVersion (English) | 15.8 MB | Adobe PDF | View/Open |
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