The influence of visual and tactile perception on hand control in children with Duchenne muscular dystrophy
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Citações na Scopus
12
Tipo de produção
article
Data de publicação
2014
Editora
WILEY-BLACKWELL
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Autores
XAVIER, Gilberto Fernando
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Citação
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, v.56, n.9, p.882-887, 2014
Resumo
AIM To investigate tactile perception and manual dexterity, with or without visual feedback, in males with Duchenne muscular dystrophy (DMD). METHOD Forty males with DMD (mean age 9y 8mo, SD 2y 3mo; range 5-14y), recruited from the teaching hospital of the School of Medicine of the University of Sao Paulo, with disease severity graded as '1' to '6' on the Vignos Scale and '1' on Brooke's Scale, and 49 healthy males (mean age 8y 2mo; range 5-11y; SD 1y 11mo), recruited from a local education center, participated in the study. We assessed tactile perception using two-point discrimination and stereognosis tests, and manual dexterity using the Pick-Up test with the eyes either open or closed. Analysis of variance was used to compare groups; a p value of less than 0.05 was considered statistically significant. RESULTS Males with DMD exhibited no impairment in tactile perception, as measured by the two-point discrimination test and the number of objects correctly named in the stereognosis test. Manipulation during stereognosis was statistically slower with both hands (p<0.001), and manual dexterity was much worse in males with DMD when there was no visual feedback (p<0.001). INTERPRETATION Males with DMD exhibited disturbances in manipulation during stereognosis and dexterity tests. Hand control was highly dependent on visual information rather than on tactile perception. Motor dysfunction in males with DMD, therefore, might be related to altered neural control.
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Referências
- Amirjani N, 2007, MUSCLE NERVE, V35, P788, DOI 10.1002/mus.20750
- BROOKE MH, 1981, MUSCLE NERVE, V4, P186, DOI 10.1002/mus.880040304
- Costa MF, 2007, AM J HUM GENET, V80, P1064, DOI 10.1086/518127
- Cotton S, 1998, CHILD NEUROPSYCHOL, V4, P110, DOI 10.1076/chin.4.2.110.3183
- Cyrulnik SE, 2008, J INT NEUROPSYCH SOC, V14, P853, DOI 10.1017/S135561770808106X
- Cyrulnik SE, 2007, J PEDIATR, V150, P474, DOI 10.1016/j.jpeds.2006.12.045
- Di Lazzaro V, 1998, MUSCLE NERVE, V21, P662
- Essex C, 2001, BRIT MED J, V323, P37, DOI 10.1136/bmj.323.7303.37
- Gao JH, 1996, SCIENCE, V272, P545, DOI 10.1126/science.272.5261.545
- Haenggi T, 2006, CELL MOL LIFE SCI, V63, P1614, DOI 10.1007/s00018-005-5461-0
- Herman RP, 2006, DEV MED CHILD NEUROL, V38, P255
- King BR, 2010, NEUROSCI LETT, V483, P36, DOI 10.1016/j.neulet.2010.07.056
- Krumlinde Sundholm LK, 2002, DEV MED CHILD NEUROL, V44, P604
- Lee JS, 2002, MUSCLE NERVE, V26, P506, DOI 10.1002/mus.10238
- Manzur AY, 2009, J NEUROL NEUROSUR PS, V80, P706, DOI 10.1136/jnnp.2008.158329
- Mazzone ES, 2012, DEV MED CHILD NEUROL, V54, P879, DOI 10.1111/j.1469-8749.2012.04345.x
- Moura MC, 2010, DEV MED CHILD NEUROL, V52, P10
- Pare M, 1999, EXP BRAIN RES, V125, P239, DOI 10.1007/s002210050679
- Polatkan S, 1998, Microsurgery, V18, P192
- Proske U, 2009, J PHYSL, V17, P4139
- Ribot-Ciscar E, 2004, MUSCLE NERVE, V29, P861, DOI 10.1002/mus.20044
- Sundholm LK, 1998, DEV MED CHILD NEUROL, V40, P4
- VIGNOS P J Jr, 1960, J Chronic Dis, V12, P273, DOI 10.1016/0021-9681(60)90105-3
- Witney AG, 2004, TRENDS NEUROSCI, V27, P637, DOI 10.1016/j.tins.2004.08.006
- Zar JH, 1984, BIOSTATISTICAL ANAL