Strategies to reduce blood transfusion: a Latin-American perspective

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP HAJJAR, Ludhmila Abrahao FMUSP-HC
ALMEIDA, Juliano Pinheiro de FMUSP-HC
OSAWA, Eduardo Atsushi FMUSP-HC
GALAS, Filomena Regina Barbosa Gomes FMUSP-HC 2015
dc.identifier.citation CURRENT OPINION IN ANESTHESIOLOGY, v.28, n.1, p.81-88, 2015
dc.identifier.issn 0952-7907
dc.description.abstract Purpose of review Anemia has been demonstrated to be detrimental in several populations such as high-surgical-risk patients, critically ill elderly, and cardiac patients. Red blood cell transfusion is the most commonly prescribed therapy for anemia. Despite being life-saving, it carries a risk that ranges from mild complications to death. The aim of this review is to discuss the risks of anemia and blood transfusion, and to describe recent developments in the strategies to reduce allogeneic blood transfusion. Recent findings In the past decades, clinical studies comparing transfusion strategies in different populations were conducted. Despite the challenges imposed by the development of such studies, evidence-based medicine on transfusion medicine in critically ill patients is being created. Different results arising from these studies reflect population heterogeneity, specific circumstances, and difficulties in measuring the impact of anemia and transfusion in a clinical trial. Summary An adequate judgment of a clinical condition associated with proper application of the available literature is the cornerstone in the management of transfusion in critical care. Apart from this individualized strategy, the institution of a patient blood management program allows goal-directed approach through preoperative recognition of anemia, surgical efforts to minimize blood loss, and continuous assessment of the coagulation status.
dc.language.iso eng
dc.relation.ispartof Current Opinion in Anesthesiology
dc.rights restrictedAccess
dc.subject anemia; blood transfusion; individualized approach; patient blood management
dc.subject.other critically-ill patients; bypass graft-surgery; cardiac-surgery; cell transfusion; cardiopulmonary bypass; preoperative anemia; clinical-practice; restrictive transfusion; critical-care; mortality
dc.title Strategies to reduce blood transfusion: a Latin-American perspective
dc.type article
dc.rights.holder Copyright LIPPINCOTT WILLIAMS & WILKINS LIM/08
dc.identifier.doi 10.1097/ACO.0000000000000144
dc.identifier.pmid 25486489
dc.type.category review
dc.type.version publishedVersion HAJJAR, Ludhmila Abrahao:FM:MCP FUKUSHIMA, Julia Tizue:HC:ICESP ALMEIDA, Juliano Pinheiro de:HC:ICESP OSAWA, Eduardo Atsushi:HC:ICESP GALAS, Filomena Regina Barbosa Gomes:FM:MCG WOS:000347394200012 2-s2.0-84920735484 PHILADELPHIA USA
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dc.description.index MEDLINE
dc.identifier.eissn 1473-6500
hcfmusp.citation.scopus 5
hcfmusp.citation.wos 5

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