Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium

Show simple item record

dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author TOPORCOV, Tatiana Natasha
ZNAOR, Ariana
ZHANG, Zuo-Feng
YU, Guo-Pei
WINN, Deborah M.
WEI, Qingyi
VILENSKY, Marta
VAUGHAN, Thomas
THOMSON, Peter
TALAMINI, Renato
SZESZENIA-DABROWSKA, Neonila
STURGIS, Erich M.
SMITH, Elaine
SHANGINA, Oxana
SCHWARTZ, Stephen M.
SCHANTZ, Stimson
RUDNAI, Peter
RICHIARDI, Lorenzo
RAMROTH, Heribert
PURDUE, Mark P.
OLSHAN, Andrew F.
ELUF-NETO, Jose FMUSP-HC
MUSCAT, Joshua
MOYSES, Raquel Ajub FMUSP-HC
MORGENSTERN, Hal
MENEZES, Ana
MCCLEAN, Michael
MATSUO, Keitaro
MATES, Dana
MACFARLANE, Tatiana V.
LISSOWSKA, Jolanta
LEVI, Fabio
LAZARUS, Philip
VECCHIA, Carlo La
LAGIOU, Pagona
KOIFMAN, Sergio
KJAERHEIM, Kristina
KELSEY, Karl
HOLCATOVA, Ivana
HERRERO, Rolando
HEALY, Claire
HAYES, Richard B.
FRANCESCHI, Silvia
FERNANDEZ, Leticia
FABIANOVA, Eleonora
DAUDT, Alexander W.
CURIONI, Otavio Alberto
MASO, Luigino Dal
CURADO, Maria Paula
CONWAY, David I.
CHEN, Chu
CASTELLSAGUE, Xavier
CANOVA, Cristina
CADONI, Gabriella
BRENNAN, Paul
BOCCIA, Stefania
ANTUNES, Jose Leopoldo Ferreira
AHRENS, Wolfgang
AGUDO, Antonio
BOFFETTA, Paolo
HASHIBE, Mia
LEE, Yuan-Chin Amy
WUENSCH FILHO, Victor
dc.date.issued 2015
dc.identifier.citation INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, v.44, n.1, p.169-185, 2015
dc.identifier.issn 0300-5771
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/9449
dc.description.abstract Background: Increasing incidence of head and neck cancer (HNC) in young adults has been reported. We aimed to compare the role of major risk factors and family history of cancer in HNC in young adults and older patients. Methods: We pooled data from 25 case-control studies and conducted separate analyses for adults <= 45 years old ('young adults', 2010 cases and 4042 controls) and > 45 years old ('older adults', 17 700 cases and 22 704 controls). Using logistic regression with studies treated as random effects, we estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Results: The young group of cases had a higher proportion of oral tongue cancer (16.0% in women; 11.0% in men) and unspecified oral cavity / oropharynx cancer (16.2%; 11.1%) and a lower proportion of larynx cancer (12.1%; 16.6%) than older adult cases. The proportions of never smokers or never drinkers among female cases were higher than among male cases in both age groups. Positive associations with HNC and duration or pack-years of smoking and drinking were similar across age groups. However, the attributable fractions (AFs) for smoking and drinking were lower in young when compared with older adults (AFs for smoking in young women, older women, young men and older men, respectively, =19.9% (95% CI = 9.8%, 27.9%), 48.9% (46.6%, 50.8%), 46.2% (38.5%, 52.5%), 64.3% (62.2%, 66.4%); AFs for drinking = 5.3% (-11.2%, 18.0%), 20.0% (14.5%, 25.0%), 21.5% (5.0%, 34.9%) and 50.4% (46.1%, 54.3%). A family history of early-onset cancer was associated with HNC risk in the young [OR = 2.27 (95% CI = 1.26, 4.10)], but not in the older adults [OR = 1.10 (0.91, 1.31)]. The attributable fraction for family history of early-onset cancer was 23.2% (8.60% to 31.4%) in young compared with 2.20% (-2 .41%, 5.80%) in older adults. Conclusions: Differences in HNC aetiology according to age group may exist. The lower AF of cigarette smoking and alcohol drinking in young adults may be due to the reduced length of exposure due to the lower age. Other characteristics, such as those that are inherited, may play a more important role in HNC in young adults compared with older adults.
dc.description.sponsorship · US National Institutes of Health
· National Cancer Institute [R03CA113157]
· National Institute of Dental and Craniofacial Health [R03DE016611]
· Italian Association for Research on Cancer (AIRC)
· Italian League Against Cancer
· Italian Ministry of Research
· Swiss League against Cancer [KFS1069-09-2000]
· Fribourg League against Cancer [FOR381.88]
· Swiss Cancer Research [AKT 617]
· Gustave-Roussy Institute [88D28]
· Swiss League against Cancer
· Swiss Research against Cancer/Oncosuisse [KFS-700, OCS-1633]
· World Cancer Research Fund
· European Commission INCO-COPERNICUS Program [IC15-CT98-0332]
· National Institutes of Health (NIH) US [P01CA068384 K07CA104231, R01CA078609, R01CA100679]
· NIH [R01CA048996, R01DE012609, NIDCR R01DE11979, NIDCR R01DE13110, NIH FIRCA TW01500, R01CA61188, P01CA068384, K07CA104231, R01DE13158, P50CA90388, R01DA11386, R03CA77954, T32CA09142, U01CA96134, R21ES011667, R01ES11740, R01CA100264, R01CA51845, R01CA30022]
· Veterans Affairs Merit Review Funds
· National Institute of Environmental Health Sciences [P30ES010126]
· Alper Research Program for Environmental Genomics of the UCLA Jonsson Comprehensive Cancer Center
· National Institutes of Health (NCI) US
· NIDCR intramural programmes
· Fondo para la Investigacion Cientifica y Tecnologica (FONCYT) Argentina
· IMIM (Barcelona)
· Fundacao de Amparo a Pesquisa no Estado de Sao Paulo (FAPESP) [01/01768-2]
· European Commission [IC18-CT97-0222]
· IARC multicentre study: Fondo de Investigaciones Sanitarias (FIS) of the Spanish Government [FIS 97/0024, FIS 97/0662, BAE 01/5013]
· International Union Against Cancer (UICC)
· Yamagiwa-Yoshida Memorial International Cancer Study Grant
· AIRC (Italian Agency for Research on Cancer) [10068]
· US multicentre study: the Intramural Program of the NCI, NIH, United States
· Sao Paulo study: Fundacao de Amparo a Pesquisa no Estado de Sao Paulo (FAPESP) [04/12054-9, 10/51168-0]
· European Community [QLK1-CT-2001-00182]
· German Ministry of Education and Research [01GB9702/3]
· Ministry of Education, Science, Sports, Culture and Technology of Japan [17015052]
· Ministry of Health, Labour and Welfare of Japan [H20-002]
dc.language.iso eng
dc.publisher OXFORD UNIV PRESS
dc.relation.ispartof International Journal of Epidemiology
dc.rights openAccess
dc.subject Head and neck neoplasms; adult; smoking; alcohol drinking; diet
dc.subject.other squamous-cell carcinoma; upper aerodigestive tract; aged 45 years; oral-cancer; pharyngeal cancer; tobacco use; epidemiology consortium; genetic susceptibility; human-papillomavirus; international head
dc.title Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium
dc.type article
dc.rights.holder Copyright OXFORD UNIV PRESS
dc.description.group LIM/28
dc.description.group LIM/38
dc.identifier.doi 10.1093/ije/dyu255
dc.identifier.pmid 25613428
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author ELUF-NETO, Jose:FM:MPR
hcfmusp.author MOYSES, Raquel Ajub:HC:LIM/28
hcfmusp.author.external · TOPORCOV, Tatiana Natasha:Univ Sao Paulo, Fac Saude Publ, BR-01246904 Sao Paulo, SP, Brazil
· ZNAOR, Ariana:Croatian Natl Canc Registry, Zagreb, Croatia
· ZHANG, Zuo-Feng:Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA
· YU, Guo-Pei:Peking Univ, Med Informat Ctr, Beijing 100871, Peoples R China; New York Med Coll, Valhalla, NY 10595 USA
· WINN, Deborah M.:NCI, Bethesda, MD 20892 USA
· WEI, Qingyi:UT MD Anderson Canc Ctr, Houston, TX USA
· VILENSKY, Marta:Univ Buenos Aires, Inst Oncol Angel H Roffo, Buenos Aires, DF, Argentina
· VAUGHAN, Thomas:Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA; Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
· THOMSON, Peter:Univ Newcastle, Sch Dent Sci, Newcastle Upon Tyne, Tyne & Wear, England
· TALAMINI, Renato:Aviano Canc Ctr, I-33081 Aviano, Italy
· SZESZENIA-DABROWSKA, Neonila:Inst Occupat Med, Lodz, Poland
· STURGIS, Erich M.:UT MD Anderson Canc Ctr, Houston, TX USA
· SMITH, Elaine:Univ Iowa, Coll Publ Hlth, Iowa City, IA USA
· SHANGINA, Oxana:Russian Acad Med Sci, Canc Res Ctr, Moscow, Russia
· SCHWARTZ, Stephen M.:Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA; Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
· SCHANTZ, Stimson:New York Eye & Ear Infirm, New York, NY 10003 USA
· RUDNAI, Peter:Natl Inst Environm Hlth, Budapest, Hungary
· RICHIARDI, Lorenzo:Univ Turin, Canc Epidemiol Unit, Dept Med Sci, Turin, Italy
· RAMROTH, Heribert:Heidelberg Univ, Inst Publ Hlth, Heidelberg, Germany
· PURDUE, Mark P.:NCI, Bethesda, MD 20892 USA
· OLSHAN, Andrew F.:Univ N Carolina, Sch Publ Hlth, Chapel Hill, NC USA
· MUSCAT, Joshua:Penn State Coll Med, Hershey, PA USA
· MORGENSTERN, Hal:Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA; Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 USA; Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA
· MENEZES, Ana:Univ Fed Pelotas, Pelotas, Brazil
· MCCLEAN, Michael:Boston Univ, Sch Publ Hlth, Boston, MA USA
· MATSUO, Keitaro:Aichi Canc Ctr, Res Inst, Nagoya, Aichi 464, Japan
· MATES, Dana:Inst Publ Hlth, Bucharest, Romania
· MACFARLANE, Tatiana V.:Univ Aberdeen, Sch Dent, Aberdeen, Scotland
· LISSOWSKA, Jolanta:M Skasodowska Curie Mem Canc Ctr, Warsaw, Poland; Inst Oncol, Dept Canc Epidemiol & Prevent, Warsaw, Poland
· LEVI, Fabio:CHU Vaudois, IUMSP, CH-1011 Lausanne, Switzerland; Univ Lausanne, Lausanne, Switzerland
· LAZARUS, Philip:Washington State Univ, Coll Pharm, Spokane, WA USA
· VECCHIA, Carlo La:Ist Ric Farmacol Mario Negri, IRCCS, Milan, Italy; Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy
· LAGIOU, Pagona:Univ Athens, Sch Med, GR-11527 Athens, Greece
· KOIFMAN, Sergio:Fundacao Osvvaldo Cruz, Escola Nacl Saude Publ, Rio De Janeiro, Brazil
· KJAERHEIM, Kristina:Canc Registry Norway, Oslo, Norway
· KELSEY, Karl:Brown Univ, Dept Pathol & Lab Med, Providence, RI 02912 USA
· HOLCATOVA, Ivana:Charles Univ Prague, Fac Med 1, Prague, Czech Republic
· HERRERO, Rolando:WHO, Int Agcy Res Canc, Prevent & Implementat Grp, Lyon, France
· HEALY, Claire:Trinity Coll Sch Dent Sci, Dublin, Ireland
· HAYES, Richard B.:NYU, Sch Med, Div Epidemiol, New York, NY USA
· FRANCESCHI, Silvia:Int Agcy Res Canc, F-69372 Lyon, France
· FERNANDEZ, Leticia:Inst Oncol & Radiobiol, Havana, Cuba
· FABIANOVA, Eleonora:Reg Author Publ Hlth Banska Bystrica, Banska Bystrica, Slovakia
· DAUDT, Alexander W.:Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
· CURIONI, Otavio Alberto:Secretaria Estado Saude Sao Paulo, Hosp Heliopolis, Sao Paulo, Brazil
· MASO, Luigino Dal:Aviano Canc Ctr, I-33081 Aviano, Italy
· CURADO, Maria Paula:Int Prevent Res Inst, Lyon, France
· CONWAY, David I.:Univ Glasgow, Sch Dent, Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland
· CASTELLSAGUE, Xavier:CIBER ESP, IDIBELL, ICO, Barcelona, Spain
· CANOVA, Cristina:Univ Padua, Padua, Italy
· CADONI, Gabriella:Univ Cattolica Sacro Cuore, Inst Otorhinolaryngol, Rome, Italy
· BRENNAN, Paul:Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
· BOCCIA, Stefania:Univ Cattolica Sacro Cuore, Inst Publ Hlth, Rome, Italy
· ANTUNES, Jose Leopoldo Ferreira:Univ Sao Paulo, Fac Saude Publ, BR-01246904 Sao Paulo, SP, Brazil
· AHRENS, Wolfgang:BIPS, Leibniz Inst Prevent Res & Epidemiol, Bremen, Germany; Univ Bremen, Inst Stat, Fac Math & Comp Sci, D-28359 Bremen, Germany
· AGUDO, Antonio:IDIBELL, ICO, Barcelona, Spain
· BOFFETTA, Paolo:Mt Sinai Sch Med, Tisch Canc Inst, New York, NY USA
· HASHIBE, Mia:Univ Utah, Sch Med, Huntsnnan Canc Inst, Salt Lake City, UT USA
· LEE, Yuan-Chin Amy:Univ Utah, Sch Med, Dept Family & Prevent Med, Div Publ Hlth, Salt Lake City, UT 84112 USA
· WUENSCH FILHO, Victor:Univ Sao Paulo, Fac Saude Publ, BR-01246904 Sao Paulo, SP, Brazil
hcfmusp.origem.id 2-s2.0-84924584545
hcfmusp.origem.id WOS:000350864200024
hcfmusp.publisher.city OXFORD
hcfmusp.publisher.country ENGLAND
hcfmusp.relation.reference · Andisheh-Tadbir A, 2010, J CRANIOFAC SURG, V21, P126, DOI 10.1097/SCS.0b013e3181c46c10
· Annertz K, 2002, INT J CANCER, V101, P95, DOI 10.1002/ijc.10577
· Benhamou S, 2004, INT J CANCER, V112, P901, DOI 10.1002/ijc.20474
· BLOT WJ, 1988, CANCER RES, V48, P3282
· Boing AF, 2010, J EPIDEMIOL COMMUNIT, V65, P709
· Bosetti C, 2003, CANCER EPIDEM BIOMAR, V12, P1091
· Brenner DR, 2010, BMC CANCER, V10, DOI 10.1186/1471-2407-10-285
· BYERS RM, 1975, AM J SURG, V130, P475, DOI 10.1016/0002-9610(75)90487-0
· Chen KX, 2009, HEAD NECK-J SCI SPEC, V31, P175, DOI 10.1002/hed.20946
· Chen WY, 2011, JAMA-J AM MED ASSOC, V306, P1884, DOI 10.1001/jama.2011.1590
· Chuang SC, 2012, CANCER CAUSE CONTROL, V23, P69, DOI 10.1007/s10552-011-9857-x
· Conway DI, 2009, ORAL ONCOL, V45, P743, DOI 10.1016/j.oraloncology.2009.02.007
· Cui Y, 2006, INT J CANCER, V118, P714, DOI 10.1002/ijc.21413
· Dietz A, 2004, INT J CANCER, V108, P907, DOI 10.1002/ijc.11658
· Elahi A, 2002, CARCINOGENESIS, V23, P1229, DOI 10.1093/carcin/23.7.1229
· Falaki F, 2011, MED ORAL PATOL ORAL, V16, pE473, DOI 10.4317/medoral.16.e473
· Ferlay J, 2010, GLOBOCAN 2008 V1 2 C
· FRANCESCHI S, 1990, CANCER RES, V50, P6502
· Friedlander PL, 1998, HEAD NECK-J SCI SPEC, V20, P363, DOI 10.1002/(SICI)1097-0347(199808)20:5<363::AID-HED1>3.0.CO;2-W
· Funk GF, 2002, HEAD NECK-J SCI SPEC, V24, P165, DOI 10.1002/hed.10004
· Galli P, 2009, BMC CANCER, V9, DOI 10.1186/1471-2407-9-137
· Gawecki W, 2007, EUR ARCH OTO-RHINO-L, V264, P1459, DOI 10.1007/s00405-007-0386-x
· Gupta P C, 1999, J Indian Med Assoc, V97, P370
· Hart AKE, 1999, OTOLARYNG HEAD NECK, V120, P828, DOI 10.1016/S0194-5998(99)70322-0
· Hashibe M, 2006, CANCER EPIDEM BIOMAR, V15, P696, DOI 10.1158/1055-9965.EPl-05-0/10
· Hashibe M, 2007, J NATL CANCER I, V99, P777, DOI 10.1093/jnci/djk179
· Hayes RB, 1999, CANCER CAUSE CONTROL, V10, P27, DOI 10.1023/A:1008876115797
· Herrero R, 2003, J NATL CANCER I, V95, P1772, DOI 10.1093/jnci/djg/107
· Hirota SK, 2008, MED ORAL PATOL ORAL, V13, pE227
· Hyam DM, 2003, AUST DENT J, V48, P50, DOI 10.1111/j.1834-7819.2003.tb00009.x
· Iype EM, J POSTGRAD MED, V47, P171
· Kleinbaum D, 1982, EPIDEMIOLOGIC RES PR
· Kmietowicz Z, 2009, BRIT MED J, V339, DOI 10.1136/bmj.b3293
· KURIAKOSE M, 1992, ORAL ONCOL, V28B, P113
· Lagiou P, 2009, EUR J CANCER PREV, V18, P76, DOI 10.1097/CEJ.0b013e32830c8dca
· Levi F, 1998, INT J CANCER, V77, P705, DOI 10.1002/(SICI)1097-0215(19980831)77:5<705::AID-IJC8>3.0.CO;2-Z
· Lissowska J, 2010, CANCER CAUSE CONTROL, V21, P1091, DOI 10.1007/s10552-010-9537-2
· Llewellyn CD, 2004, ORAL ONCOL, V40, P304, DOI 10.1016/j.oraloncology.2003.08.015
· Llewellyn CD, 2003, ORAL ONCOL, V39, P106, DOI 10.1016/S1368-8375(02)00026-X
· Llewellyn CD, 2001, ORAL ONCOL, V37, P401, DOI 10.1016/S1368-8375(00)00135-4
· Llewellyn CD, 2004, J ORAL PATHOL MED, V33, P525, DOI 10.1111/j.1600-0714.2004.00222.x
· Luna-Ortiz Kuauhyama, 2011, Acta Otorrinolaringol Esp, V62, P113, DOI 10.1016/j.otorri.2010.09.016
· Macfarlane TV, 2010, CANCER CAUSE CONTROL, V21, P2213, DOI 10.1007/s10552-010-9641-3
· Mackenzie J, 2000, ORAL ONCOL, V36, P387, DOI 10.1016/S1368-8375(00)00009-9
· Mafi N, 2012, ASIAN PAC J CANCER P, V13, P3373, DOI 10.7314/APJCP.2012.13.7.3373
· Muscat JE, 1996, CANCER RES, V56, P5192
· NEGRI E, 1993, CANCER EPIDEM BIOMAR, V2, P189
· Negri E, 2009, INT J CANCER, V124, P394, DOI 10.1002/ijc.23848
· Olshan AF, 2000, CANCER EPIDEM BIOMAR, V9, P185
· Patel SC, 2011, J CLIN ONCOL, V29, P1488, DOI 10.1200/JCO.2010.31.7883
· Percy CL, 1990, INT CLASSIFICATION D
· Peters ES, 2005, CANCER EPIDEM BIOMAR, V14, P476, DOI 10.1158/1055-9965.EPI-04-0431
· Purdue MP, 2009, AM J EPIDEMIOL, V169, P132, DOI 10.1093/aje/kwn306
· Robinson KL, 2003, ORAL ONCOL, V39, P31, DOI 10.1016/S1368-8375(02)00014-3
· Rodriguez T, 2004, ORAL ONCOL, V40, P207, DOI 10.1016/S1368-8375(03)00168-4
· ROGERS MAM, 1993, CANCER EPIDEM BIOMAR, V2, P305
· Rosenblatt KA, 2004, CANCER RES, V64, P4049, DOI 10.1158/0008-5472.CAN-03-3425
· SANKARANARAYANAN R, 1989, BRIT J CANCER, V59, P439, DOI 10.1038/bjc.1989.89
· Santos-Silva AR, 2011, HISTOPATHOLOGY, V58, P1127, DOI 10.1111/j.1365-2559.2011.03863.x
· SCHANTZ SP, 1989, CANCER, V64, P1232, DOI 10.1002/1097-0142(19890915)64:6<1232::AID-CNCR2820640612>3.0.CO;2-U
· Schantz SP, 1997, LARYNGOSCOPE, V107, P765, DOI 10.1097/00005537-199706000-00011
· SCHANTZ SP, 1989, JAMA-J AM MED ASSOC, V262, P3313, DOI 10.1001/jama.262.23.3313
· SCHANTZ SP, 1988, CANCER, V62, P1374, DOI 10.1002/1097-0142(19881001)62:7<1374::AID-CNCR2820620723>3.0.CO;2-M
· Shiboski CH, 2005, CANCER-AM CANCER SOC, V103, P1843, DOI 10.1002/cncr.20998
· Siegelmann-Danieli N, 1998, J CLIN ONCOL, V16, P745
· Siriwardena BSMS, 2006, ORAL ONCOL, V42, P831, DOI 10.1016/j.oraloncology.2005.12.001
· Smith EM, 1998, LARYNGOSCOPE, V108, P1098, DOI 10.1097/00005537-199807000-00027
· Suzuki T, 2006, CANCER SCI, V97, P760, DOI 10.1111/j.1349-7006.2006.00232.x
· Szymanska K, 2011, CANCER CAUSE CONTROL, V22, P1037, DOI 10.1007/s10552-011-9779-7
· Thomas L, 2012, ANN OTO RHINOL LARYN, V121, P395
· Twardella D, 2006, J CLIN EPIDEMIOL, V59, P82, DOI 10.1016/j.jclinepi.2005.05.003
· United States Public Health Service Health Care Financing Administration Centers for Disease Control and Prevention (U.S.) Centers for Medicare & Medicaid Services (U.S.) National Center for Health Statistics (U.S.), 1995, ICD9CM HLTH CAR FIN
· Verschuur HP, 1999, LARYNGOSCOPE, V109, P249, DOI 10.1097/00005537-199902000-00015
· World Health Organization, 2005, INT STAT CLASS DIS R
· Zhang ZD, 2005, CANCER EPIDEM BIOMAR, V14, P1188, DOI 10.1158/1055-9965.EPI-04-0501
dc.description.index MEDLINE
dc.identifier.eissn 1464-3685
hcfmusp.citation.scopus 60
hcfmusp.citation.wos 54
hcfmusp.affiliation.country Brasil
hcfmusp.affiliation.country Noruega
hcfmusp.affiliation.country Grécia
hcfmusp.affiliation.country Suíça
hcfmusp.affiliation.country Escócia
hcfmusp.affiliation.country Espanha
hcfmusp.affiliation.country Japão
hcfmusp.affiliation.country Rússia
hcfmusp.affiliation.country Polônia
hcfmusp.affiliation.country Inglaterra
hcfmusp.affiliation.country Argentina
hcfmusp.affiliation.country Croácia
hcfmusp.affiliation.country Estados Unidos
hcfmusp.affiliation.country Alemanha
hcfmusp.affiliation.country Itália
hcfmusp.affiliation.country Hungria
hcfmusp.affiliation.country Romênia
hcfmusp.affiliation.country Eslováquia
hcfmusp.affiliation.country Cuba
hcfmusp.affiliation.country Irlanda
hcfmusp.affiliation.country França
hcfmusp.affiliation.country República Tcheca
hcfmusp.citation.toppaper Highly


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace



Browse

My Account

Statistics