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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | MIRANDA, Aline P. de | - |
dc.contributor.author | SILVA, Cely B. | - |
dc.contributor.author | MIMICA, Lycia M. J. | - |
dc.contributor.author | MOSCOVICI, Bernardo K. | - |
dc.contributor.author | MALAVAZZI, Gustavo R. | - |
dc.contributor.author | HIDA, Richard Y. | - |
dc.date.accessioned | 2015-07-01T20:57:23Z | - |
dc.date.available | 2015-07-01T20:57:23Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | JOURNAL OF CATARACT AND REFRACTIVE SURGERY, v.41, n.1, p.135-139, 2015 | - |
dc.identifier.issn | 0886-3350 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/9536 | - |
dc.description.abstract | PURPOSE: To evaluate the in vitro antimicrobial activity of aqueous humor in patients who had preoperative topical application of moxifloxacin hydrochloride 0.5%. SETTING: Department of Ophthalmology, Santa Casa de Misericordia de Sao Paulo, Brazil. DESIGN: Comparative case series. METHODS: Twenty-nine eyes from 29 cataract surgery patients were included in this study. In the study group (n = 15 eyes), 3 topical applications of moxifloxacin hydrochloride 0.5% were administered preoperatively; in the control group (n = 14 eyes), no topical applications were administered. Aqueous humor samples were collected and stored in sterile microtubes at -80 degrees C until analysis. Antimicrobial analysis was performed using standard strains with standard sterile filter paper disks. Inhibition halos were measured in millimeters, and both bactericidal and bacteriostatic effects were analyzed. RESULTS: Inhibition halos were observed on most of the study group plates except those with Streptococcus pneumoniae: Escherichia coli (13.93 mm +/- 0.64 [SD]), Klebsiella pneumoniae (10.63 +/- 0.61 mm), Staphylococcus aureus (7.47 +/- 0.68 mm), and S epidermidis (4.20 +/- 3.33 mm) The differences between the mean inhibition halo diameters were statistically significant (P < .0001) in all samples. No bactericidal effect was observed against any of the microorganisms studied. CONCLUSIONS: After topical application of moxifloxacin 0.5%, aqueous humor showed bacteriostatic effect against E coli, K pneumoniae, S aureus, and S epidermidis. No bactericidal effect was observed against any of the microorganisms evaluated. No antimicrobial effect against S pneumoniae was observed. | - |
dc.language.iso | eng | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.relation.ispartof | Journal of Cataract and Refractive Surgery | - |
dc.rights | restrictedAccess | - |
dc.subject.other | cataract-surgery | - |
dc.subject.other | gatifloxacin 0.3-percent | - |
dc.subject.other | ophthalmic solution | - |
dc.subject.other | endophthalmitis | - |
dc.subject.other | penetration | - |
dc.subject.other | prophylaxis | - |
dc.subject.other | fluoroquinolones | - |
dc.subject.other | ciprofloxacin | - |
dc.subject.other | antibiotics | - |
dc.subject.other | eyedrops | - |
dc.title | In vitro antimicrobial analysis of aqueous humor after topical application of moxifloxacin hydrochloride 0.5% | - |
dc.type | article | - |
dc.rights.holder | Copyright ELSEVIER SCIENCE INC | - |
dc.identifier.doi | 10.1016/j.jcrs.2014.11.010 | - |
dc.identifier.pmid | 25532640 | - |
dc.subject.wos | Ophthalmology | - |
dc.subject.wos | Surgery | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | MIRANDA, Aline P. de:Univ Sao Paulo, Santa Casa Misericordia Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil | - |
hcfmusp.author.external | SILVA, Cely B.:Univ Sao Paulo, Santa Casa Misericordia Sao Paulo, Dept Microbiol, Sao Paulo, Brazil | - |
hcfmusp.author.external | MIMICA, Lycia M. J.:Univ Sao Paulo, Santa Casa Misericordia Sao Paulo, Dept Microbiol, Sao Paulo, Brazil | - |
hcfmusp.author.external | MOSCOVICI, Bernardo K.:Univ Sao Paulo, Santa Casa Misericordia Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil | - |
hcfmusp.author.external | MALAVAZZI, Gustavo R.:Univ Sao Paulo, Santa Casa Misericordia Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil | - |
hcfmusp.description.beginpage | 135 | - |
hcfmusp.description.endpage | 139 | - |
hcfmusp.description.issue | 1 | - |
hcfmusp.description.volume | 41 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84919430755 | - |
hcfmusp.origem.id | WOS:000347671300021 | - |
hcfmusp.publisher.city | NEW YORK | - |
hcfmusp.publisher.country | USA | - |
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dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1873-4502 | - |
hcfmusp.citation.scopus | 4 | - |
hcfmusp.scopus.lastupdate | 2024-03-28 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - ODS/03 |
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