Aging of the Lungs in Asymptomatic Lifelong Nonsmokers: Findings on HRCT

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art_WINTER_Aging_of_the_Lungs_in_Asymptomatic_Lifelong_Nonsmokers_2015.PDF (467.61 KB)
Citações na Scopus
34
Tipo de produção
article
Data de publicação
2015
Editora
SPRINGER
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
MANZINI, Marcos
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
LUNG, v.193, n.2, p.283-290, 2015
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
To report lung parenchymal findings on high-resolution computed tomography (HRCT) in a population of asymptomatic, never-smoker urban dwellers aged 65 years and older. After institutional approval, asymptomatic older patients from the Geriatrics Outpatient Clinic aged 65 years and older (older group) and healthy volunteers aged 30-50 years (younger group) were invited to participate in the study. Asymptomatic, never-smoker subjects considered free of relevant disease after spirometry and echocardiography underwent chest HRCT. Three researchers reviewed every scan, noting the absence/presence and distribution of pre-specified parenchymal findings. Statistical comparisons between groups were performed using appropriate tests with the aid of software. Forty-seven older and 24 younger subjects were included in this analysis. A higher proportion of women and a longer history of urban dwelling were present in the older group. Parenchymal findings were more prevalent in the older group (78.7 vs. 25 % in the younger group; p < 0.001). Parenchymal bands (59.6 vs. 25 %; p = 0.007), ground-glass opacities (25.5 vs. 0 %; p = 0.006), and septal lines (21.3 vs. 0 %; p = 0.013) were more prevalent in the elderly. When only subjects aged 75 years and older were considered as the older group, micronodules, reticular opacities, cysts, and bronchiectases (19.1 vs. 0 % for all comparisons; p = 0.04) were also more frequently found among the elderly. Parenchymal bands, ground-glass opacities, septal lines, bronchiectasis, micronodules, reticular opacities, and lung cysts were more prevalent among the elderly.
Palavras-chave
Aging, Elderly, Lung, Normal, High-resolution computed tomography
URI
https://observatorio.fm.usp.br/handle/OPI/9676
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/09
Artigos e Materiais de Revistas Científicas - LIM/22