Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/9888
Title: Air pollution and children's health: sickle cell disease
Authors: BARBOSA, Silvia Maria de MacedoFARHAT, Sylvia Costa LimaMARTINS, Lourdes ConceicaoPEREIRA, Luiz Alberto AmadorSALDIVA, Paulo Hilario NascimentoZANOBETTI, AntonellaBRAGA, Alfesio Luis Ferreira
Citation: CADERNOS DE SAUDE PUBLICA, v.31, n.2, p.265-275, 2015
Abstract: The hallmarks of sickle cell disease are anemia and vasculopathy. The aim of this study was to assess the association between air pollution and children's emergency room visits of sickle cell patients. We adopted a case-crossover design. Daily counts of children's and adolescents' sickle cell disease emergency room visits from the pediatric emergency unit in Sao Paulo, Brazil, were evaluated from September 1999 to December 2004, matching by temperature, humidity and controlling for day of the week. Interquartile range increases of the four-day moving averages of PM10, NO2, SO2, CO, and O-3 were associated with increases of 18.9% (95%CI: 11.2-26.5), 19% (95%CI: 8.3-29.6), 14.4% (95%CI: 6.5-22.4), 16,5% (95%CI: 8.9-24.0), and 9.8% (95%CI: 1.1-18.6) in total sickle cell emergency room visits, respectively. When the analyses were stratified by pain, PM10 was found to be 40.3% higher than in sickle cell patients without pain symptoms. Exposure to air pollution can affect the cardiovascular health of children and may promote a significant health burden in a sensitive group.
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Artigos e Materiais de Revistas Científicas - FM/MPT
Departamento de Patologia - FM/MPT

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Instituto da Criança - HC/ICr

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Instituto do Coração - HC/InCor

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LIM/05 - Laboratório de Poluição Atmosférica Experimental

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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