UBIRATAN DE PAULA SANTOS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
9 resultados
Resultados de Busca
Agora exibindo 1 - 9 de 9
- Electronic cigarettes-the new playbook and revamping of the tobacco industry(2018) SANTOS, Ubiratan Paula
- Smoking - family structure of origin and other determining factors(2018) MAIA, Keyla Medeiros; FONTES, Cor Jesus Fernandes; SANTOS, Ubiratan Paula
conferenceObject Silicosis in a Rutile Mining, Bahia/Brazil(2018) VASCONCELOS, I. M.; SERRA, J. P.; JESUS, R. M.; LOMBARDI, E. M.; SANTOS, U. P.- Burnt sugarcane harvesting work: effects on pulmonary and systemic inflammatory markers(2018) LEITE, Marceli Rocha; ZANETTA, Dirce Maria Trevisan; ANTONANGELO, Leila; MARCAL, Lia Junqueira; RAMOS, Dionei; BURDMANN, Emmanuel Almeida; SANTOS, Ubiratan PaulaObjective: To evaluate the effects of burnt sugarcane harvesting on the plasmatic and urinary concentrations of the club cell secretory protein (CC16) and inflammatory systemic biomarkers in a group of sugarcane cutters.Methods: Seventy-eight sugar cane workers were evaluated. The plasmatic and urinary concentrations of CC16, a pulmonary damage marker and inflammatory systemic biomarkers were collected at three time points: before, three months after and six months after the onset of the burnt sugarcane harvesting period. All evaluations were performed at approximate to 7 am, before the daily work shift. In the three-month evaluation, a post-work shift assessment (acute effect) was also performed.Results: The age of the workers was 37.911.0years. The PM2.5 concentrations were 27.0 (23.0-33.0) and 101.0 (31.0-139.5) mu g/m(3) in the pre harvest and harvest periods, respectively (p<.001). Burnt sugarcane harvesting was associated with a reduction, throughout the work during burnt sugarcane harvesting (subchronic effect), in plasmatic and urinary CC16 concentrations. Acutely, there was a decrease in plasmatic concentrations. There were acute and subchronic increases in inflammatory markers (neutrophils, monocytes) and muscle damage markers (CK and LDH) and a decrease in red blood cells.Conclusions: Harvesting of burnt sugarcane was associated with acute and subchronic reductions in the plasmatic and urinary concentrations of CC16 protein and changes in systemic inflammatory markers.
- Socioeconomic and quality of life impact of work-related asthma in Sao Paulo, Brazil(2018) ROIO, Lavinia Clara Del; TERRA-FILHO, Mario; SANTOS, Ubiratan Paula
- Clinical, functional and biomarkers differences between subjects exposed to silica, with and without silicosis(2018) LOMBARDI, Elisa; PRADO, Gustavo Faibischew; TERRA FILHO, Mario; SANTOS, Ubiratan Paula
- Evaluation of peak expiratory flow in adolescents and its association with inhalable particulate in a Brazilian medium-sized city(2018) MISSAGIA, Suelem; AMARAL, Camila Alves Silva do; JESUS, Alessandra Santos de; ARBEX, Marcos Abdo; SANTOS, Ubiratan de Paula; ANDRÉ, Carmem Diva Saldiva de; ANDRÉ, Paulo Afonso de; SALDIVA, Paulo Hilário do Nascimento; MARTINS, Lourdes Conceição; BRAGA, Alfésio Luís Ferreira; PEREIRA, Luiz Alberto AmadorABSTRACT: Introduction: High particulate matter (PM10) concentrations are associated with increased incidence of respiratory symptoms and decreased lung function. This study evaluates the air pollution effects in children’s and adolescents’ lung function using peak expiratory flow (PEF) measurements over a given period, in an area exposed to industrial emissions. Methodology: This was a panel study. The effects of air pollution on respiratory symptoms and PEF were investigated in 117 children and adolescents from three public schools in areas of exposure to air pollution from a mining company in a Brazilian medium-sized city, from 2008 to 2009. The average daily PM10, temperature and humidity were recorded by the monitoring network in the region. Association between daily records of PEF and PM10 was assessed in mixed-effect regression models, controlling for temperature, humidity, and body mass index. Results: About 60,000 PEF measurements were performed. Increases of 14µg/m3 in PM10 were associated with decreased PEF in the morning (-1.04%, 95%CI -1.32; -0.77) and evening (-1.2%, 95%CI -1.49, -0.92). Discussion: We found a significant negative association between particulate matter and peak expiratory flow rate in this population, and these remained significant even after adjusted for temperature, humidity, body mass index, coughing, wheezing and coryza. Conclusion: Adverse effects were found and it suggests an association between increase in PM10 and reduced lung function.
- Worker in a tatami factory: Case report of asthma in a complex and multiple occupational exposure(2018) COLARES, Philippe; ASSUNCAO, Gabriela Lins Medeiros De; TAKIZAWA, Daniel Bruno; LOMBARDI, Elisa Maria Siqueira; MIZUTANI, Rafael Futoshi; PRADO, Gustavo Faibischew; TERRA-FILHO, Mario; SANTOS, Ubiratan De Paula
- O trabalho no corte de cana-de-açúcar, riscos e efeitos na saúde: revisão da literatura(2018) LEITE, Marceli Rocha; ZANETTA, Dirce Maria Trevisan; TREVISAN, Iara Buriola; BURDMANN, Emmanuel de Almeida; SANTOS, Ubiratan de PaulaOBJECTIVE: Describe the main work risks for sugarcane cutters and their effects on workers' health. METHODS: Critical review of articles, with bibliographic research carried out in the PubMed, SciELO Medline, and Lilacs databases. The following keywords were used: sugarcane workers, sugarcane cutters, sugarcane harvesting, cortadores de cana-de-acucar, and colheita de cana-de-acucar. The inclusion criteria were articles published between January 1997 and June 2017, which evaluated working conditions and health effects on sugarcane cutters. Those that did not deal with the work impact of cutting burned and unburnt sugarcane in the cutter's health were excluded. The final group of manuscripts was selected by the lead author of this study and reviewed by a co-author. Disagreements were resolved by consensus using the predefined inclusion and exclusion criteria and, where necessary, the final decision was made by consulting a third co-author. RESULTS: From the 89 articles found, 52 met the selection criteria and were evaluated. Studies have shown that cutters work under conditions of physical and mental overload, thermal overload, exposure to pollutants, and are subject to accidents. The main effects observed were respiratory, cardiovascular, renal, musculoskeletal, heat stress, dehydration, genotoxic, and those due to accidents. CONCLUSIONS: Work on the manual cutting of sugarcane, especially of burned sugarcane, exposes workers to various risks, with different health impacts. Risk reduction for exposure to pollution and thermal and physical overload is required as a measure to preserve the health of the worker.