GUSTAVO FAIBISCHEW PRADO
Projetos de Pesquisa
Unidades Organizacionais
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
3 resultados
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- A real-life study of the effectiveness of different pharmacological approaches to the treatment of smoking cessation: re-discussing the predictors of success(2011) PRADO, Gustavo Faibischew; LOMBARDI, Elisa Maria Siqueira; BUSSACOS, Marco Antonio; ARRABAL-FERNANDES, Frederico Leon; TERRA-FILHO, Mario; SANTOS, Ubiratan de PaulaOBJECTIVE: To evaluate the effectiveness of nicotine replacement therapy (NRT), bupropion, nortriptyline and combination therapy and describe factors associated with treatment success. INTRODUCTION: Clinical trials clearly demonstrate the efficacy of pharmacotherapy in smoking cessation. However, it is only after its use in real-life settings that clinical effectiveness and limitations of a treatment are fully known. METHODS: Patients attended a four-session cognitive-behavioral program and received medicines free of charge. Abstinence from smoking was assessed at each visit. RESULTS: A total of 868 smokers (68.8% women) were included. Their mean age was 49.6 years; the amount smoked was 25 cigarettes/day and the Fagerstrom Score was 6.6. Abstinence rates after 6 months and 1 year were 36.5% and 33.6%. In univariate analysis, male gender, age (> 50), higher number of cigarettes smoked, cardiovascular comorbidities, longer interval from the last cigarette and combined treatment of nortriptyline plus NRT were predictive of abstinence, while neuropsychiatric comorbidities and the answer ""yes'' to the question ""Do you smoke more often during the first hours after waking'' were correlated with failure. In a multivariate model, predictors of abstinence were neuropsychiatric comorbidities, the answer ""yes'' to the question ""Do you smoke more often during the first hours after waking'' and combined treatment of nortriptyline plus NRT. Male gender and a longer period from the last cigarette were correlated with lower abstinence rate. CONCLUSION: Satisfactory success rates were obtained in a teaching hospital. Factors such as age, daily cigarette consumption, number of pack-years and dependency score were not reliable markers of abstinence. The combination nortriptyline+NRT was independently associated with higher abstinence rates.
article 24 Citação(ões) na Scopus II Guidelines for Perioperative Evaluation of the Brazilian Society of Cardiology(2011) YU, Pai Ching; CALDERARO, Daniela; CARAMELLI, Bruno; FEITOSA, Alina Coutinho Rodrigues; MARQUES, Andre Coelho; AYUB, Beatriz; POLANCZYK, Carisi A.; JARDIM, Carlos; VIEIRA, Carolina L. Zilli; PINHO, Claudio; IEZZI, Denise; GUALANDRO, Danielle Menosi; IKEOKA, Dimas T.; SCHREEN, Dirk; D'AMICO, Elbio Antonio; PFEFERMAN, Elcio; LIMA, Emerson Quintino de; BURDMANN, Emmanuel de A.; PACHON, Enrique; MACHADO, Fabio Santana; GALAS, Filomena Regina Barbosa Gomes; PAULA, Flavio Jota de; CARVALHO, Francine Correa de; FEITOSA-FILHO, Gilson Soares; PRADO, Gustavo Faibischew; LOPES, Heno F.; LIMA, Jose Jaime Galvao de; MARCHINI, Julio Flavio Meirelles; FORNARI, Luciana S.; DRAGER, Luciano F.; VACANTI, Luciano Janussi; HAJJAR, Ludhmila Abrahao; ROHDE, Luis Eduardo P.; GOWDAK, Luis Henrique; CARDOSO, Luiz Francisco; VIEIRA, Marcelo Luiz Campos; MONACHINI, Maristela C.; MACATRAO, Milena; VILLACA, Paula Ribeiro; FARSKY, Pedro Silvio; LOPES, Renato Delascio; BAGNATORI, Renato Scotti; HEINISCH, Roberto Henrique; GUALANDRO, Sandra F. Menosi; ACCORSI, Tarso Augusto Duenhas; AVILA, Walkiria Samuel; MATHIAS JR., Wilson- Women and smoking: Risks, impacts, and challenges(2011) LOMBARDI, Elisa Maria Siqueira; PRADO, Gustavo Faibichew; SANTOS, Libiratan de Paula; FERNANDES, Frederico Leon ArrabalSmoking among women has drawn increasing attention because of the increase (or less pronounced decrease) in its prevalence when compared with that observed for men, as well as because of the specific effects that smoking has on women's health. For the 2010 ""World No Tobacco Day"", the World Health Organization chose the theme ""Gender and tobacco with an emphasis on marketing to women"", with the aim of encouraging policies to combat marketing strategies employed by the tobacco industry and to curb the epidemic of smoking among women. In this article, we discuss the characteristics of smoking among women, addressing factors such as smoking prevalence, nicotine dependence, the role of the tobacco industry, health risks, approaches to smoking cessation, treatment strategies, and prevention measures.