ALBERTO QUEIROZ FARIAS

(Fonte: Lattes)
Índice h a partir de 2011
12
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Gastroenterologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico

Resultados de Busca

Agora exibindo 1 - 10 de 28
  • article 44 Citação(ões) na Scopus
    Epidemiology of HCC in Brazil: incidence and risk factors in a ten-year cohort
    (2014) PARANAGUA-VEZOZZO, Denise C.; ONO, Suzane K.; ALVARADO-MORA, Monica V.; FARIAS, Alberto Q.; CUNHA-SILVA, Marlone; FRANCA, Joao I. D.; ALVES, Venancio A. F.; SHERMAN, Morris; CARRILHO, Flair Jose
    Background and aim. The lack of information about hepatocellular carcinoma (HCC) in Brazil weakens health policy in preventing deaths from the illness. The aim of this study was to establish the cumulative incidence and the risk factors for hepatocellular carcinoma development in patients under a surveillance program. Material and methods. 884 patients with compensated cirrhosis were prospectively followed up for at least five years, from August 1998 until August 2008, with at least one annual ultrasonography liver examination and serum alpha fetoprotein (AFP) measurement. Results. Among 884 patients, 72 (8.1%) developed a tumor with a median follow up of 21.4 months. In the hepatocellular carcinoma group, hepatitis C virus infection was the major etiological factor (65.3%), 56.9% (41/72) were male and the mean average age was 57 +/- 10 years. The annual incidence of hepatocellular carcinoma was 2.9%. 79.2% (57/72) of HCCs were detected within Milan Criteria, and the mean survival time was 52.3 months, significantly higher than for those outside Milan, with a mean time of 40.6 months (p = 0.0003). Conclusion. The annual incidence of HCC among this large series of Brazilian cirrhotic patients was around 2.9% with a detection rate of 8.1%, or a cumulative incidence rate over five years of 14.3%. The three variables related to HCC risk were low serum albumin [HR: 0.518 (0.46-0.78)], high AFP > 20 ng/mL [HR: 3.16 (1.86-5.38)], and ethnicity (Brazilian-East Asian descendants vs. other mixed Brazilian ethnicities) [HR: 2.86 (1.48-5.53)].
  • conferenceObject
    PATIENTS WITH ACUTE ON CHRONIC LIVER FAILURE ARE AT HIGHER RISK OF PROCEDURAL-RELATED BLEEDING
    (2023) INTAGLIATA, Nicolas M.; RAHIMI, Robert S.; TIJERA, Fatima Higuera De La; SIMONETTO, Douglas A.; FARIAS, Alberto Q.; MAZO, Daniel Ferraz De Campos; BOIKE, Justin Richard; STINE, Jonathan G.; SERPER, Marina; PEREIRA, Gustavo; MATTOS, Angelo; MARCIANO, Sebastian; DAVIS, Jessica; BENITEZ, Carlos; CHADHA, Ryan; MENDEZ-SANCHEZ, Nahum; DELEMOS, Andrew S.; MOHANTY, Arpan; DIRCHWOLF, Melisa Melisa; FORTUNE, Brett; NORTHUP, Patrick Grant; PATRIE, James; CALDWELL, Stephen H.
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    Robust identification of patient subgroups in acute decompensated cirrhosis
    (2023) PALOMINO, Sara; HUERGO, Estefania; USON, Eva; SANCHEZ, Cristina; LAGANI, Vincenzo; KIANI, Narsis; PLANELL, Nuria; GURBINDO, Unai; TREBICKA, Jonel; FARIAS, Alberto Q.; CARACENI, Paolo; RAUTOU, Pierre-Emmanuel; GOMEZ-CABRERO, David
  • conferenceObject
    Endogenous Heparinoid Effects during Bacterial Infections in Patients with Cirrhosis Do Not Impair Thombin Generation: A Prospective Study
    (2018) MOTTA, Marina; ROCHA, Tania Rubia Flores; MIGITA, Beatriz Yuri; BATISTA, Juliana Medeiros; D'AMICO, Elbio Antonio; D'ALBUQUERQUE, Lutz Augusto Cameiro; CARRILHO, Flair Jose; FARIAS, Alberto Q.
  • article 9 Citação(ões) na Scopus
    Early-Onset and Late-Onset Heart Failure After Liver Transplantation
    (2014) SILVESTRE, Odilson M.; FARIAS, Alberto Q.; BACAL, Fernando
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    Worldwide Lack of Early Referral of Patients with Alcoholic Liver Disease: Final Results of the Global Alcoholic Liver Disease Survey (GLADIS)
    (2017) SHAH, Neil D.; VENTURA-COTS, Meritxell; ZHANG, Chaoqun; ZAHIRAGIC, Nerma; YU, Yuanjie; YACOUB, Mohamed A.; WU, Pengbo; WANDERA, Andrew; VOROBIOFF, Julio D.; THURAIRAJAH, Prem H.; TAN, Shiyun; SPRECKIC, Sanjin; SIOW, Way; SCHEURICH, Christoph; SAEZ-ROYUELA, Federico; RODIL, Agustina; REIS, Daniela; ONO, Suzane K.; NABESHIMA, Mariana A.; TEO, Eng Kiong; KARONEY, Mercy J.; FERNANDEZ, Marlen I. Castellanos; FARIAS, Alberto Q.; DOMECH, Caridad Ruenes; COSTA, Pedro Marques Da; ALFADHLI, Ahmad; YANG, Ling; SOME, Fatma; KOCHHAR, Rakesh; KLUWE, Johannes; KIM, Won; ISAKOV, Vasily; HUSIC-SELIMOVIC, Azra; HSIANG, John C.; GEORGE, Jacob; KASSAS, Mohamed El; GURIDI, Zaily Dorta; CARRILHO, Flair J.; BESSONE, Fernando; BADIA, Ester; ALBORAIE, Mohamed; CORTEZ-PINTO, Helena; BATALLER, Ramon
  • article 9 Citação(ões) na Scopus
    Selectins and Platelet-Derived Growth Factor (PDGF) in Schistosomiasis-Associated Pulmonary Hypertension
    (2014) LAPA, Monica; ACENCIO, Milena M. P.; FARIAS, Alberto Q.; TEIXEIRA, Lisete R.; FERNANDES, Caio J. C.; JARDIM, Carlos P.; TERRA-FILHO, Mario
    The aim of this study was to evaluate the expression profiles of the relevant selectins and PDGF in schistosomiasis-associated pulmonary hypertension. Patients with three distinct clinical profiles were enrolled in the study: IPAH(n = 11), schistosomiasis-associated PH (Sch-PH))(n = 13), and schistosomiasis without PH (Sch) (n = 13). Healthy volunteers, were recruited as a control group(n = 13). Echocardiography was performed in all groups, and the PH patients underwent right heart catheterization. Plasma soluble adhesion molecules E- and P-Selectin, PDGF-AB, PDGF-BB were determined by ELISA. E-selectin was significantly increased in the IPAH group compared with the other groups [the control, Sch + PH and Sch groups) (p < 0.001) (Fig. 2)]. P-selectin was lower in Sch (20.2 + 8.9 x 103 pg/mL) as compared to the control, (43 16.8 x 103 pg/mL), IPAH (35.8 7.8 x 103 pg/mL), and Sch + PH (36.8 +/- A 15.7 x 103 pg/mL) (p = 0.005) groups. Serum PDGF-BB levels were higher in the control group (8.9 +/- A 4.8 x 103 pg/mL) compared with the IPAH (3.7 +/- A 2.17 x 103 pg/mL), Sch + PH (5.2 +/- A 3.7 x 103 pg/mL) and Sch (2.4 +/- A 1.7 x 103 pg/mL) groups (p < 0.05). PDGF-AB levels were also higher in the control group (25.6 +/- A 8.6 x 103 pg/mL), compared with the other three groups, being the Sch group the one with lower serum levels of this marker (11.4 +/- A 8.6 x 103 pg/mL) (p = 0.006). In conclusion, vascular inflammation in schistosomiasis, with or without PH, is different from IPAH suggesting distinct pathophysiological mechanisms associated with the development of pulmonary hypertension.
  • conferenceObject
    FRESH FROZEN PLASMA TRANSFUSION IN PATIENTS WITH CIRRHOSIS AND COAGULOPATHY: EFFECT ON CONVENTIONAL COAGULATION TESTS AND THROMBOMODULIN-MODIFIED THROMBIN GENERATION
    (2019) RASSI, Amanda Bruder; D'AMICO, Elbio Antonio; TRIPODI, Armando; ROCHA, Tania Rubia Flores; MIGITA, Beatriz; FERREIRA, Caroline Marcondes; CARRILHO, Flair Jose; FARIAS, Alberto Q.
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    PRIVATE INSURANCE ACCESS IS ASSOCIATED WITH HIGHER LIVER TRANSPLANT LISTING AND TRANSPLANT ACCESS AND LOWER MORTALITY COMPARED TO NATIONAL INSURANCES IN A LARGE MULTINATIONAL COHORT OF INPATIENTS WITH CIRRHOSIS
    (2023) BAJAJ, Jasmohan S.; WONG, Florence; XIE, Qing; KAMATH, Patrick S.; TOPAZIAN, Mark; HAYES, Peter C.; TORRE, Aldo; DESALEGN, Hailemichael; IDILMAN, Ramazan; CAO, Zhujun; ALVARES-DA-SILVA, Mario Reis; GEORGE, Jacob; BUSH, Brian J.; THACKER, Leroy R.; SHAW, Jawaid A.; ALBHAISI, Somaya; FISSEHA, Henok; ASRANI, Sumeet; FALLAHZADEH, Mohammad Amin; ALLAH, Belimi Hibat; DEBZI, Nabil; SETO, Wai-Kay; FUNG, James; VARGAS, Hugo E.; BAYNE, David; ALLAM, Dalia; PATWA, Yashwi Haresh Kumar; ARAVINTHAN, Aloysious; VENKATACHALAPATHY, Suresh Vasan; RAJORIYA, Neil; FAULKES, Rosemary; RAJARAM, Ruveena; ARSYAD, Nik Ma Nik; KATCHMAN, Helena; RABINOWICH, Liane; BERA, Chinmay; NAGRAL, Aabha; HAVERI, Ajay; OKEKE, Edith; NYAM, David P.; KUMAR, Shiva; THULUVATH, Paul J.; SHESHADRI, Somya; LEITH, Damien; HUEZO, Maria Sarai Gonzalez; CABRERA, Araceli Bravo; GUTIERREZ, Oscar Morales; KULKARNI, Anand V.; SHARMA, Mithun; EAPEN, C. E.; GOEL, Ashish; DUSEJA, Ajay K.; BETTINGER, Dominik; GANDOTRA, Akash; SCHULTHEISS, Michael; RAMOS-PINEDA, Abraham; TAN, Hiang Keat; LIOU, Wei Lun; BARRADAS, Mauricio Castillo; TREEPRASERTSUK, Sombat; WEJNARUEMARN, Salisa; VELAZQUEZ, Rene Male; MADE, Lilian Torres; KAPPUS, Matthew R.; WEGERMANN, Kara; DANIELLE, Adebayo; BIGGINS, Scott W.; FILIPEK, Natalia; KEAVENY, Andrew Paul; YUNG, Diana; TANDON, Puneeta; DAHIYA, Monica; HAKTANIYAN, Busra; DUARTE-ROJO, Andres; REDDY, K. Rajender Rajender; RAHEMATPURA, Suditi; SARAYA, Anoop; RELA, Mohamed; GUNDUZ, Feyza; ASLAN, Rahmi; YILDIRIM, Abdullah Emre; BARUTCU, Sezgin; ARORA, Anil; KUMAR, Ashish; VERNA, Elizabeth; TUDEHOPE, Fiona; MARCIANO, Sebastian; GADANO, Adrian; KARASU, Zeki; UYSAL, Alper; UCBILEK, Enver; KOSAY, Tolga; VELASCO, Jose Antonio Velarde-Ruiz; FELIX-TELLEZ, Francisco; ADANIR, Haydar; DINCER, Dinc; DHIMAN, Radhakrishna; ROY, Akash; FAISAL, Nabiha; ANAND, Anil Chandra; PRAHARAJ, Dibyalochan; GIBSON, Robert; PRUDENCE, Alexander; XIAN, Yongchao; GUAN, Jin; ZHU, Chuanwu; WANG, Yingling; SU, Man; GAO, Yanhang; WANG, Xinrui; JIANG, Yongfang; PENG, Feng; ZHAO, Caiyan; WANG, Wang; WANG, Lei; YIN, Dedong; LIU, Mingquin; CAI, Yijing; WANG, Xiaozhong; GUO, Feng; ZHANG, Ningping; ZHANG, Wanqin; LI, Hai; DONG, Fuchen; ZHENG, Xin; LIU, Jing; TANG, Hong; YAN, Libo; XU, Bin; WEI, Linlin; GAO, Zhiliang; XU, Zhen; GALLARDO, Jacqueline Cordova; LIN, Minghua; GAO, Haibin; WU, Xiaoping; RAO, Qunfang; ZEKRY, Amany; CHEN, Jinjun; LI, Beiling; LIU, Chenghai; ZHANG, Yanyun; DOYLE, Adam; Vi Nguyen; CHU, Elsa; HU, Peng; DENG, Huan; RIORDAN, Stephen; MICHALCZUK, Matheus; MACQUILLAN, Gerry; LI, Jie; WANG, Jian; FARIAS, Alberto Q.; ZITELI, Patricia; VICTOR, Livia; WONG, Yu Jun; HO, Wei Ling; ALEXOPOULOU, Alexandra; MANI, Iliana; BOBAT, Bilal; YASSER, Fouad; MOSTAFA, Alaa; SONAVANE, Amey; PEREZ-HERNANDEZ, Jose Luis; ZAZUETA, Godolfino Miranda; NEGRILLO, Ricardo Cabello; YEGURLA, Jatin; SARIN, Shiv Kumar; CHOUDHURY, Ashok Kumar
  • article 2 Citação(ões) na Scopus
    m-RECIST at 1 month and Child A are survival predictors after percutaneous ethanol injection of hepatocellular carcinoma
    (2014) SILVA, Mauricio F.; CARRILHO, Flair J.; PARANAGUA-VEZOZZO, Denise C.; CAMPOS, Luciana T.; NACIF, Lucas S.; DINIZ, Marcio A.; FARIAS, Alberto Q.; ALVES, Venancio A. F.; D'ALBURQUERQUE, Luis A. C.; ONO, Suzane K.
    Background and aims. Percutaneous ethanol injection (PEI) is a well-established therapeutic option in patients with cirrhosis and hepatocellular carcinoma (HCC). The modified-Response Evaluation Criteria in Solid Tumors (m-RECIST) are an important tool for the assessment of HCC response to therapy. The aim was to evaluate whether HCC response according to the m-RECIST criteria could be an effective predictor of Long-term survival in Barcelona Clinic Liver Cancer (BCLC) stage 0 and A HCC patients undergoing PEI. Material and methods. 79 patients were followed-up for median time of 26.8 months. HCC diagnosis was based on the,current guidelines of the American Association for Study of the Liver Diseases (AASLD) and European Association for Study of the Liver (EASL). Patient survival was calculated from the first PEI session to the end of the follow-up. Results. The 1-, 3-, and 5-year overall survival rates were 79, 48 and 37%, respectively. In the multivariate analysis, Child-Pugh-Turcotte (CPT) (p = 0.022) and the response to m-RECIST criteria (p = 0.016) were associated with patient survival. CPT A patients who achieved Complete Response (CR) 1 month after PEI presented a 5-year survival rate of 55%. By contrast, the worst scenario, the group with CPT B but without CR had a 5-year survival rate of 9%, while the group with either CPT A or CR as a survival predictor had a 5-year survival rate of 31%. In conclusion, in BCLC stage 0 and A HCC-patients, m-RECIST at 1 month and Child A may predict survival rates after PEI.