ALBERTO QUEIROZ FARIAS
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Gastroenterologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
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conferenceObject URINARY BIOMARKER NGAL IN PATIENTS WITH HEPATORENAL SYNDROME: ACCURACY STUDY IN PREDICTION OF NO RESPONSE TO THERAPY WITH ALBUMIN AND TERLIPRESSIN(2016) XIMENES, R. O.; HELOU, C.; DINIZ, M.; BARBEIRO, D.; SOUZA, H.; D'ALBUQUERQUE, L. A.; CARRILHO, F.; FARIAS, A.bookPart Sangramento Gastrintestinal(2016) ROCHA, Evandra Cristina Vieira da; SPOSETO, Valdinélia Bomfim Barban; FARIAS, Alberto QueirozconferenceObject Fresh Frozen Plasma Transfusion Ameliorates INR and aPTT but Does Not Increase Thrombomodulin-Corrected Thrombin Generation in Patients with Cirrhosis(2016) RASSI, Amanda Bruder; ROCHA, Tania R. F. R.; FARIAS, Alberto Q.; MARIANO, Livia Caroline Barbosa; D'AMICO, Elbio Antonio- Liver Transplantation in Brazil(2016) BITTENCOURT, Paulo Lisboa; FARIAS, Alberto Queiroz; COUTO, Claudia AlvesOver 1700 liver transplantations (LTs) are performed annually in Brazil. In absolute terms, the country performs more LT surgeries than anywhere else in Latin America and is third worldwide. However, due to its increasing population and inadequate donor organ supply, the country averages 5-10 LTs per million population, far lower than required. There is a marked heterogeneity in organ donation and LT activity throughout the country. Access to LT in the underprivileged North, Midwest, and Northeast regions of Brazil is scarce. Major challenges for the future of LT in Brazil will be to increase organ donation and access to LT. The reduction of those geographical disparities in donation, organ procurement, and LT due to political and financial constraints is of utmost importance. Liver Transplantation 22 1254-1258 2016 AASLD
bookPart Cirrose(2016) BITTENCOURT, Paulo Lisboa; FARIAS, Alberto Queiroz; COUTO, Cláudia AlvesbookPart Hepatite Fulminante e Transplante Hepático: Aspectos Clínicos(2016) FARIAS, Alberto Queiroz; GONçALVES, Luciana Lofêgo; BITTENCOURT, Paulo LisboabookPart Doenças Hepáticas Causadas por Bactérias, Parasitas e/ou Fungos(2016) CALY, Wanda Regina; FARIAS, Alberto Queiroz; RABELO, Fabiola; BAPTISTA, Daniel Machado; CARRILHO, Flair JoséconferenceObject CORONARY ARTERY CALCIUM SCORE AND FRAMINGHAM SCORE IN EVALUATION OF CARDIOVASCULAR RISK AFTER LIVER TRANSPLANTATION(2016) CARONE, L.; OLIVEIRA, C. P.; ALVARES-DA-SILVA, M. R.; STEFANO, J. T.; TERRABUIO, D. R. B.; ABDALA, E.; CARRILHO, F. J.; FARIAS, A. Q.; D'ALBUQUERQUE, L. A. C.conferenceObject URINARY BIOMARKER NGAL IN PATIENTS WITH CIRRHOSIS AND BACTERIAL INFECTIONS: ACCURACY STUDY IN ACUTE KIDNEY INJURY PREDICTION DEFINED BY KDIGO CRITERIA(2016) XIMENES, R. O.; HELOU, C.; DINIZ, M.; BARBEIRO, D.; SOUZA, H.; D'ALBUQUERQUE, L. A.; CARRILHO, F.; FARIAS, A.- Patients with cirrhosis in the ED: early predictors of infection and mortality(2016) XIMENES, Rafael Oliveira; FARIAS, Alberto Queiroz; SCALABRINI NETO, Augusto; DINIZ, Marcio Augusto; KUBOTA, Gabriel Taricani; IVO, Mauricio Menezes Aben-Athar; COLACIQUE, Caroline Gracia Plena Sol; D'ALBUQUERQUE, Luiz Augusto Carneiro; DIAS, Roger DagliusBackground: Patients with cirrhosis have high risk of bacterial infections and cirrhosis decompensation, resulting in admission to emergency department (ED). However, there are no criteria developed in the ED to identify patients with cirrhosis with bacterial infection and with high mortality risk. Study objective: The objective of the study is to identify variables from ED arrival associated with bacterial infections and in hospital mortality. Methods: This is a retrospective single-center study using a tertiary hospital's database to identify consecutive ED patients with decompensated cirrhosis. Clinical variables and laboratory results were obtained by chart review. Logistic regression models were built to determine variables independently associated with bacterial infection and mortality. Scores using these variables were designed. Results: One hundred forty-nine patients were enrolled, most of them males (77.9%) with alcoholic cirrhosis (53%) and advanced liver disease (Child-Pugh C, 47.2%). Bacterial infections were diagnosed in 72 patients (48.3%), and 36 (24.2%) died during hospital stay. Variables independently associated with bacterial infection were lymphocytes less than or equal to 900/mm(3) (odds ratio [OR], 3.85 [95% confidence interval {CI}, 1.47-10]; P = .006) and C-reactive protein greater than 59.4 mg/L (OR, 5.05 [95% CI, 1.93-13.2]; P = .001). Variables independently associated with mortality were creatinine greater than 1.5 mg/dL (OR, 4.35 [95% CI, 1.87-10.1]; P = .001) and international normalized ratio greater than 1.65 (OR, 3.71 [95% CI, 1.6-8.61]; P = .002). Scores designed to predict bacterial infection and mortality (Mortality in Cirrhosis Emergency Department Score) had an area under the receiver operating characteristic curve of 0.82 and 0.801, respectively. The Mortality in Cirrhosis Emergency Department Score performed better than Model for End-Stage Liver Disease score. Conclusions: In this cohort of ED patients with decompensated cirrhosis, lymphopenia and elevated C-reactive protein were related to bacterial infections, and elevated creatinine and international normalized ratio were related to mortality. Scores built with these variables should be prospectively validated.