FELIPE DALESSANDRO FERREIRA CORCHS
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Anorexia nervosa, paternalism and clinical practice(2014) MEDEIROS, Gustavo Costa; SAMPAIO, Daniela Guimaraes; CORCHS, Felipe
- Traumatic memory retrieval followed by electroconvulsive therapy as a treatment for posttraumatic stress disorder: A pilot study(2023) ARAUJO, Alvaro Cabral; CARUI, Nickolas; GUIRADO, Alia Garrudo; SCHILLER, Daniela; NETO, Francisco Lotufo; CORCHS, FelipeDelivering electroconvulsive therapy (ECT) during the reconsolidation of traumatic memories may enhance the treatment efficacy in posttraumatic stress disorder (PTSD). To test this, 14 patients with severe and refractory PTSD were randomly allocated to receive ECT sessions either after retrieving the traumatic (n=8) or a neutral (n=6) memory. We found that delivering ECT after retrieving the traumatic memory enhanced the improvement of PTSD symptoms and the reduction of subjective reactivity to the traumatic memory. Reduction in anxiety and mood symptoms and physiological reactivity to the traumatic memory were observed in the sample as a whole regardless of memory retrieval.
- Risk factors for reduction in adherence to protective measures following coronavirus disease 2019 (COVID-19) vaccination and vaccine perceptions among healthcare workers, in Sao Paulo, Brazil(2023) LOPEZ, Andres Mello; BORGES, Igor Carmo; LUNA-MUSCHI, Alessandra; PERES, Carlos Henrique Mesquita; CARRENO, Paolo Gripp; OLIVEIRA, Arthur Magalhaes de; ALMEIDA, Humberto Bertola Siqueira de; MARQUES, Vivian Helena de Castro; CORCHS, Felipe; LEVIN, Anna Sara; COSTA, Silvia Figueiredo; SARTORI, Ana Marli ChristovamA survey evaluated 2,300 healthcare workers following the first dose of a coronavirus disease 2019 (COVID-19) vaccine in a tertiary-quaternary hospital in Sao Paulo, Brazil. Adherence to protective measures following vaccination was compared to previous non-work-related behaviors. Younger age, previous COVID-19, and burnout symptoms were associated with reduced adherence to mitigation measures.
- Deep brain stimulation of the subgenual cingulum and uncinate fasciculus for the treatment of posttraumatic stress disorder(2022) HAMANI, Clement; DAVIDSON, Benjamin; CORCHS, Felipe; ABRAHAO, Agessandro; NESTOR, Sean M.; RABIN, Jennifer S.; NYMAN, Alexander J.; PHUNG, Liane; GOUBRAN, Maged; LEVITT, Anthony; TALAKOUB, Omid; GIACOBBE, Peter; LIPSMAN, NirDeep brain stimulation (DBS) has been investigated for neuropsychiatric disorders. In this phase 1 trial, we treated four posttraumatic stress disorder (PTSD) patients with DBS delivered to the subgenual cingulum and the uncinate fasciculus. In addition to validated clinical scales, patients underwent neuroimaging studies and psycho -physiological assessments of fear conditioning, extinction, and recall. We show that the procedure is safe and potentially effective (55% reduction in Clinical Administered PTSD Scale scores). Posttreatment imaging data revealed metabolic activity changes in PTSD neurocircuits. During psychophysiological assessments, patients with PTSD had higher skin conductance responses when tested for recall compared to healthy controls. After DBS, this objectively measured variable was significantly reduced. Last, we found that a ratio between recall of extin-guished and nonextinguished conditioned responses had a strong correlation with clinical outcome. As this variable was recorded at baseline, it may comprise a potential biomarker of treatment response.
- Self-reported bruxism in patients with post-traumatic stress disorder(2024) SOLIS, Ana Cristina de Oliveira; CORCHS, Felipe; DURAN, erica Panzani; SILVA, Claudio; REAL, Natalia Del; ARAUJO, alvaro Cabral; WANG, Yuan-Pang; LOTUFO-NETO, FranciscoObjective The present study aimed to investigate the association between self-reported awake/sleep bruxism, and orofacial pain with post-traumatic stress disorder (PTSD). Methods A case-control study with a convenience sample was designed. Participants were recruited from a university-based Trauma Ambulatory. The diagnosis of PTSD was established through a clinical interview and the Structured Clinical Interview (SCID-I/P). Thirty-eight PTSD patients and 38 controls completed the Research Diagnostic Criteria for Temporomandibular Disorders Axis-II to categorize awake/sleep bruxism and orofacial pain. Following this, we performed a short clinical examination of the temporomandibular joint and extraoral muscles. Results Adjusted logistic regression analysis showed that awake bruxism was associated with PTSD (OR = 3.38, 95% CI = 1.01-11.27, p = 0.047). Sleep bruxism was not associated with any covariate included in the model. In a Poisson regression model, PTSD (IRR = 3.01, 95% CI = 1.38-6.55, p = 0.005) and the muscle pain/discomfort (IRR = 5.12, 95% CI = 2.80-9.36, p < 0.001) were significant predictors for current orofacial pain. Conclusions PTSD was associated with self-reported awake bruxism and low-intensity orofacial pain. These conditions were frequent outcomes in patients previously exposed to traumatic events. Clinical relevance We suggest including a two-question screening for bruxism in psychiatry/psychology interviews to improve under-identification and to prevent harmful consequences at the orofacial level.
- Impacts of the first wave of the COVID-19 pandemic on leisure and transportation physical activity among healthcare workers(2024) GURGEL, Aline Rachel Bezerra; GUIMARAES, Jean Augusto Coelho; BRUM, Patricia Chakur; LIMA, Antonio Carlos Pedroso de; GIAVINA-BIANCHI, Pedro; PERES, Carlos Henrique Mesquita; FRANCISCO, Maria Cristina Peres Braido; SANTOS, Lanuse Garcia Neves dos; SANTOS, Rita de Cassia Cezar; SANTOS, Roseli Eliana Beseggio; CORA, Aline; DUARTE, Alberto Jose da Silva; LAZARI, Carolina dos Santos; PEREIRA, Antonio Jose; SABINO, Ester Cerdeira; CORCHS, Felipe; SEGURADO, Aluisio Cotrim; COSTA, Silvia Figueiredo; LEVIN, Anna S.Introduction: The COVID-19 pandemic may lead to reduced physical activity (PA) in health care workers (HCWs). Objective: To evaluate leisure and transport-related PA in HCW of a COVID-19-dedicated hospital during the first wave of the COVID-19 pandemic. Methods: This is a cross-sectional study with a sample of 1,527 HCWs. Socioeconomic aspects, occupational characteristics, and engagement in leisure and transport-related PA were investigated through an online survey administered in August of 2020. Results: More than 80 % HCWs performed < 150 min/week of leisure-related PA, and 85 % performed <= 30 min/ day transport-related PA. Being male was associated with more PA (OR: 1.93; 95 % CI:1.40-2.66) and transportrelated PA; working in nursing, physical therapy, and cleaning/housekeeping services was associated with low PA (OR: 0.70; 95 % CI:0.51-0.95). Physicians and administrative staff were less active in transport-related PA. Conclusions: HCWs working in a COVID-19 hospital had low levels of PA in the domains of leisure and transportation.