CELSO RICARDO FERNANDES DE CARVALHO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina - Docente
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina - Líder
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- Exercise effects in adults with asthma(2022) MCLOUGHLIN, R. F.; URROZ, P. D.; MCDONALD, V. M.; CARVALHO, C. R. F.; MCDONALD, V. M.Asthma is a common chronic disease, affecting over 339 million people worldwide. People with asthma present with episodes of symptoms such as shortness of breath, wheezing, coughing, and chest tightness, which can be triggered by a variety of factors. However not all asthma is the same. The severity, frequency, duration, and symptoms vary, making asthma a complex heterogeneous disease, with many triggers of symptoms. Exercise is one such trigger that induces asthma symptoms, however, despite this exercise remains important for people with asthma and can usually be performed safely in this population. Indeed, people with asthma are recommended to engage in regular physical activity. Despite this, low levels of physical activity are still being reported in those living with asthma, particularly in those with severe disease. This unnecessary avoidance of physical activity and exercise results in negative health consequences including poorer respiratory functioning, increased disease severity, and healthcare use, decreased physical and mental health, and decreased quality of life. This chapter discusses the available evidence in relation to the benefits of regular exercise training in asthma. Several physiological and psychological benefits are reported including improved asthma control, fewer asthma symptoms and exacerbations, reduced medication and healthcare use including reduced emergency department visits, improved health status, and decreased symptoms of anxiety and depression. Although there is a paucity of evidence regarding the mechanisms responsible for the beneficial effects of exercise training in asthma, a number of mechanisms have been proposed which will also be explored. Finally, based on the currently available evidence clinical practice recommendations for exercise prescribers are provided using the FITT (frequency, intensity, time, and type) principles for exercise prescription, as well important safety considerations that should be taken into account. However, more research is required to determine optimal exercise prescription principles within the asthma population. © 2022 Elsevier Inc. All rights reserved.
bookPart 0 Citação(ões) na Scopus Occupational allergy in elite runners(2014) TEIXEIRA, R. N.; ROMANHOLO, B. S.; AGONDI, R. C.; PINTO, A. F.; MARTINS, M. de Arruda; CARVALHO, C. R. F.Background: The prevalence of allergy, asthma and airwayinflammation and hyperresponsiveness in elite athletes has increased overthe years and appears to vary between sport modalities. Although allergicand respiratory diseases have been extensively studied in enduranceathletes, especially swimmers and winter sports athletes, the prevalencein elite runners remains unknown.Objective: The aims of this study were to screen allergy symptoms inelite runners and to evaluate the airway responsiveness and airwayinflammatory cells in these athletes.Methods: One hundred and thirty elite runners were invited tocomplete the Allergy Questionnaire for Athletes (AQUA©), a validatedquestionnaire to screen allergy in athletes, in addition to answeringquestions related to training history, running distance per week and bestrace time in a marathon or half-marathon. A subgroup of 36 nonasthmaticathletes also performed the methacholine challenge test,sputum induction and cardiopulmonary exercise testing. Airwayinflammation was quantified via cellular airway infiltration.Results: The presence of allergy was based on the AQUA© totalscore, and athletes were classified as either AQUA+ or AQUA- (a score=5 or <5, respectively). Sixty-one athletes (60%) reported allergysymptoms, and no significant differences between the groups (AQUA+and AQUA-) were observed regarding gender, age, running experience,weekly training volume or best performance time in a half-marathon ormarathon (p>0.05). Most athletes presented airway inflammation witheosinophilic predominance (23.6%); however, only 8.3% of the eliterunners had a positive response to methacoline challenge.Conclusions: Our study demonstrated that elite runners have a highprevalence of allergy and eosinophilic airway inflammation withoutevidence of airway hyperresponsiveness; this finding was independent ofgender, age, quantity of training and performance. © 2014 Nova Science Publishers, Inc. All rights reserved.