DEBORA MARIA BEFI LOPES
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina - Docente
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina
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- Language assessment of children with severe liver disease in a public service in Brazil(2017) DE-PAULA, EricaMacedo; PORTA, Gilda; TANNURI, Ana Cristina Aoun; TANNURI, Uenis; BEFI-LOPES, Debora MariaOBJECTIVE: The aim of this research was to compare language development (expressive and receptive skills) in children awaiting liver transplantation with that of children who have already undergone the surgical procedure. METHODS: An observational, descriptive, cross-sectional study was conducted with 76 children divided into groups, as follows: 31 children who were candidates for liver transplantation (Group 1; G1), 45 children who had already undergone liver transplantation (Group 2; G2), and a control group (CG) of 60 healthy, normally developing children. Health status information was gathered, and the Test of Early Language Development (TELD)-3 was used to assess language skills. Family household monthly income data were also gathered using a specific questionnaire. RESULTS: G1 had poorer language performance compared with G2 and the CG. G2 had lower language performance when compared with the CG. However, when considering the TELD-3 standard scores, G2 had scores within normal limits. The regression analysis indicated age as a risk factor for language deficits in Group 1 and family income as a risk factor for language deficits in G2. CONCLUSIONS: The results suggested that children with chronic liver disease have delays in language development. Transplanted children have linguistic performance within normal limits, but their scores tended to be lower than the CG.
- A duração da pausa silente difere entre palavras de classe aberta ou fechada?(2014) PEDOTT, Paula Renata; BACCHIN, Letícia Bondezan; CÁCERES-ASSENÇO, Ana Manhani; BEFI-LOPES, Debora MariaPurpose: The study aim was to determine whether the mean duration of silent pauses depends on the word class (open or closed) and to compare the duration for each type of word between children with typical language development and children with specific language impairment (SLI). Methods: The study included 40 children with typical language development and 20 children with SLI, aged between 7 and 10 years. Each subject produced 15 story narratives based on a separate sequence of four pictures for each narrative. After the transcription of the samples, the words were classified as open class (noun, adjective, verb, adverb, and numeral) or closed class (article, preposition, pronoun, conjunction, and interjection). In the second phase of the study, the samples were analyzed using software specific to the analysis of silent pauses and the duration (milliseconds) of the pauses that occurred immediately before each of these grammatical categories was recorded. Results: In both groups, silent pauses were longer when preceding closed class words and individuals in the SLI group produced longer silent pauses than their peers did. Conclusion: The duration of a silent pause varied according to the grammatical class of the preceded word and it was shorter when followed by an open class word. In addition, the fact that individuals with SLI produce longer silent pauses than their peers confirms that their language processing is slower.
- Evolução audiométrica em usuários de implante coclear multicanal(2013) HOSHINO, Ana Cristina Hiromi; CRUZ, Dorilan Rodriguez da; GOFFI-GOMEZ, Maria Valéria Schmidt; BEFI-LOPES, Débora Maria; MATAS, Carla Gentile; FORTUNATO-TAVARES, Talita M.; TSUJI, Robinson KojiPURPOSE: to evaluate how long after activation one can achieve the desired auditory thresholds in individuals multichannel cochlear implant users from different age groups. METHOD: a retrospective cross-sectional from a database, approved by CEP / FMUSP, under number 779/06. Individuals implanted between January 2005 and September 2008, whose files had preoperative audiometric data and 3, 6 and 12 months after CI were included. Seventy-two patients fulfilled the criteria, and they were divided in two groups according to age: group I (17 year old) and GII (18-66 year old). Analysis of variance (ANOVA) of one factor in order to verify the interaction between the mean threshold and time after CI were used. RESULTS: we observed that 15 of the GI have reached around 30dBNA thresholds at 3 months after implant. The same happened to 26 patients of GII. We found significant interaction between time (F (3.140) = 91.973, p = 0.00) and the average hearing thresholds. Post-hoc analysis in the GI group were statistically significant differences for comparisons between HA and 3 months after implantation (p = 0.00) and between 3 and 12 months (p = 0.28). For GII only for comparison between HA and 3 months (p = 0.00). CONCLUSION: a significant hearing change may be observed beginning from three months after IC, but this result is not found in all implanted subjects.
- Vocabulário, consciência fonológica e nomeação rápida: contribuições para a ortografia e elaboração escrita(2012) SANTOS, Maria Thereza Mazorra dos; BEFI-LOPES, Debora MariaPURPOSE: To investigate if the performance on linguistic tasks would be predictive of orthographic domain and quality of written productions. METHODS: Participants were 82 fourth graders of Elementary Education, from public and private schools of São Paulo, with ages ranging from 9 years to 10 years and 2 months. The test battery was composed of an expressive vocabulary test, phonological awareness and rapid serial naming tasks, words and pseudowords spelling, and written text composition using a visual stimulus as a starting point. The statistical analysis included Spearman (r) correlations among all tasks. RESULTS: The results indicated that the better the vocabulary skills, the smaller the number of spelling errors and the better the quality of the written text productions, considering all the analyzed categories. Also, the higher performance in both phonological awareness and rapid object naming tasks was correlated to fewer spelling errors and written text productions with greater grammatical structure. CONCLUSION: The linguistic abilities analyzed in this study were predictive of subjects' spelling performance. The vocabulary skills were predictive of the quality of written text productions. However, phonological awareness and rapid serial naming were only predictive of children's performance concerning the syntactic and grammatical structure of their written text productions.
- Nationwide questionnaire data of 229 Williams-Beuren syndrome patients using WhatsApp tool(2021) PIRES, Lucas Vieira Lacerda; RIBEIRO, Rogerio Lemos; SOUSA, Adriana Modesto de; LINNENKAMP, Bianca Domit Werner; PONTES, Sue Ellen; TEIXEIRA, Maria Cristina Triguero Veloz; BEFI-LOPES, Debora Maria; HONJO, Rachel Sayuri; BERTOLA, Debora Romeo; KIM, Chong AeBackground: Williams-Beuren syndrome is a multisystemic disorder caused by a microdeletion of the 7q 11.23 region. Although familial cases with autosomal dominant inheritance have been reported, the vast majority are sporadic. Objective: To investigate the main complaints and clinical findings of patients with Williams-Beuren syndrome. Methods: A total of 757 parents of patients registered in the Brazilian Association of Williams-Beuren Syndrome (ABSW) received a questionnaire via WhatsApp from March to July 2017. Results: In total, 229 parents answered the survey. Age of diagnosis ranged from 2 days to 34 years (median: 3 years). The main clinical findings reported by the parents were abdominal colic (83.3%), failu re to thrive (71.5%), feeding difficulty in the first year (68.9%), otitis (56.6%), urinary tract infections (31.9%), precocious puberty (27.1%) and scoliosis (15.9%). Cardiac defects were present in 66% of patients, and the most frequent defect was supravalvular aortic stenosis (36%). Arterial hypertension was reported in 23%. Hypercalcemia was reported in 10.5% of patients, mainly during the first year of life. Hyperacusis and hypersociability were common complaints (both present in 89%). Other behavioral and neuropsychiatric symptoms reported by the parents included attention deficit (89%), anger crises (83%), excessive fear (66%), depression (64%), anxiety (67%) and hypersexuality(33%).The most common complaints were hypersensitivity to sounds, talkative personality, emotional dependence and learning difficulties. In 98.3%, the parents denied family history. Conclusions: Williams-Beuren syndrome requires close follow-up with different medical specialties due to their variable clinical comorbidities, including language and school learning difficulties, behavioral and psychiatric problems.
- How Word/Non-Word Length Influence Reading Acquisition in a Transparent Language: Implications for Children's Literacy and Development(2023) SOARES, Aparecido J. C.; SASSI, Fernanda C.; FORTUNATO-TAVARES, Talita; ANDRADE, Claudia R. F.; BEFI-LOPES, Debora M.Decoding skills are crucial for literacy development and they tend to be acquired early in transparent languages, such as Brazilian Portuguese. It is essential to better understand which variables may affect the decoding process. In this study, we investigated the processes of decoding as a function of age of children who are exposed to a transparent language. To this end, we examined the effects of grade, stimulus type and stimulus extension on the decoding accuracy of children between the ages of six and 10 years who are monolingual speakers of Brazilian Portuguese. The study included 250 children, enrolled from the first to the fifth grade. A list of words and pseudowords of variable length was created, based on Brazilian Portuguese structure. Children assessment was conducted using the computer program E-prime((R)) which was used to present the stimuli. The stimuli were programmed to appear on the screen in a random order and children were instructed to read them. The results indicate two important moments for decoding: the acquisition and the mastery of decoding skills. Additionally, the results highlight an important effect of the extent and type of stimuli and how it interacts with the school progress. Moreover, data indicate the multifactorial nature of decoding acquisition and the different interactions between variables that can influence this process. We discuss medium- and long-term implications of it, and possible individual and collective actions which can improve this process.
- Relação entre a porcentagem de consoantes corretas e a memória operacional fonológica na alteração específica de linguagem(2012) BEFI-LOPES, Debora Maria; TANIKAWA, Carol Regina; CÁCERES, Ana ManhaniPURPOSE: To verify whether age influences phonological performance and working memory, and whether there is correlation between phonological working memory and severity of phonological disorders in children with language impairment. METHODS: Participants were 30 children diagnosed with language impairment, with ages ranging from 4 to 6 years. Data from the assessment of phonological working memory and phonology (measured by the Percentage of Consonants Correct - Reviewed) were collected and statistically analyzed. RESULTS: Age did not influence phonology and phonological working memory, but there was positive correlation in the comparison between performances on phonological working memory and both phonology tasks. CONCLUSION: Age does not support the improvement of phonological abilities and phonological working memory. However, there is positive correlation between phonological working memory and the severity of phonological disorders, suggesting that the better the speech production, the better the phonological working memory.
- Investigation of auditory processing disorder and language impairment using the speech-evoked auditory brainstem response(2012) ROCHA-MUNIZ, Caroline N.; BEFI-LOPES, Debora M.; SCHOCHAT, ElianeThis study investigated whether there are differences in the Speech-Evoked Auditory Brainstem Response among children with Typical Development (TD), (Central) Auditory Processing Disorder (C) APD, and Language Impairment (LI). The speech-evoked Auditory Brainstem Response was tested in 57 children (ages 6-12). The children were placed into three groups: TD (n = 18), (C)APD (n = 18) and LI (n = 21). Speech-evoked ABR were elicited using the five-formant syllable/da/. Three dimensions were defined for analysis, including timing, harmonics, and pitch. A comparative analysis of the responses between the typical development children and children with (C)APD and LI revealed abnormal encoding of the speech acoustic features that are characteristics of speech perception in children with (C)APD and LI, although the two groups differed in their abnormalities. While the children with (C)APD might had a greater difficulty distinguishing stimuli based on timing cues, the children with LI had the additional difficulty of distinguishing speech harmonics, which are important to the identification of speech sounds. These data suggested that an inefficient representation of crucial components of speech sounds may contribute to the difficulties with language processing found in children with LI. Furthermore, these findings may indicate that the neural processes mediated by the auditory brainstem differ among children with auditory processing and speech-language disorders.
- Pretend play, vocabulary and intellectual performance of children with developmental language disorder(2021) MENDES, Janieri Braz Almeida; SANTOS, Cindy Carvalho dos; SOARES, Aparecido Jose Couto; BEFI-LOPES, Debora MariaPurpose: To verify whether the performance in the first assessment of pretend play of children with diagnostic hypothesis of developmental language disorder, correlates with the performance in formal tests of non-verbal intellectual function and both receptive and expressive vocabulary after 5 years old. Methods: The research comprised 26 subjects, 19 of whom were male, and 7 were female, with an mean age of 4:10. All participants presented a diagnostic hypothesis of developmental language disorder based on inclusion and exclusion criteria described internationally. Data were analyzed in relation to pretend play, vocabulary and performance in standardized intellectual assessment test; we also investigated correlation between them. All data underwent statistical analysis and the confidence intervals were 95%. Results: As for pretend play, it was found that most children with suspected developmental language disorder present more primitive symbolic development. Regarding vocabulary, the data show greater performance in receptive vocabulary than in expressive. In the assessment of the intelligence quotient, the children obtained, in their majority, classifications in the mean score and superior score to their age. Regarding the interaction between studied variables, no correlation was found. Conclusion: No relationship was found between the studied variables. The data are discussed in the light of international literature and promote important reflections on the symbolic-linguistic development of this population.
- Análise da ortografia de alunos do 4º ano do Ensino Fundamental a partir de ditado de palavras(2013) SANTOS, Maria Thereza Mazorra dos; BEFI-LOPES, Debora MariaPURPOSE: The purpose of this study was to establish a profile of the spelling patterns studied in students from public and private schools and to describe a word spelling task for clinical and educational settings. METHODS: Eighty-two fourth grade students belonging to the elementary school of public and private schools in São Paulo, ranging in age from nine to ten years, took part in this study. The spelling task consisted of a list of ten high frequency words (HFW), ten low frequency words (LFW), and ten pseudowords (PW), in which the typology and number of spelling errors were described. To compare the average number of mistakes on the HFWs, LFWs, and PWs, we used an analysis of variance and Tukey's multiple comparisons (p<0.05). Using a cluster analysis, homogeneous groups were formed based on their performance. RESULTS: Results indicated that the average number of mistakes in the LFWs was higher than in the HFWs (p=0.000) and PWs (p=0.000), and the number of mistakes in the HFWs was lower than in the PWs (p=0.009). The highest number of mistakes was found in the following categories: ""others"", ""rule generalization"", ""omission"", ""voiced-voiceless"", and ""addition"". There were no mistakes of the type ""ão-am"" and ""blend-separation"" in the HFWs. CONCLUSION: Spelling errors are a part of the process of learning to write, and students can show some variance in spelling performance. Furthermore, students need to be stimulated to analyze words and their aspects of phonology, morphology, and semantics. An analysis from the types of errors is not enough to plan intervention programs, but instead is necessary to understand the strategies that the child uses to write.