WILLIAM RODRIGUES TEBAR
Projetos de Pesquisa
Unidades Organizacionais
21 resultados
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- Association between Diet and Adiposity in Adults: Influence of Sedentary Behavior Patterns(2023) BERETTA, Victor Spiandor; TEBAR, William Rodrigues; SCARABOTTOLO, Catarina Covolo; DELFINO, Leandro Dragueta; SARAIVA, Bruna Thamyres Ciccotti; SANTOS, Amanda Barbosa; ANTUNES, Ewerton Pegorelli; LEOCI, Isabella Cristina; FERRARI, Gerson; CHRISTOFARO, Diego Giulliano DestroThis study analyzed the influence of sedentary behavior (SB) on the association between dietary patterns and adiposity in community-dwelling adults. Eight hundred and forty-three adults (age: 56.5 +/- 18.3 years) participated in this cross-sectional epidemiological study. Dietary patterns were evaluated using self-report questions regarding the weekly frequency of consumption of certain foods. Adiposity was determined using anthropometric measurements of weight, waist circumference, and height. SB was evaluated according to the time spent on screen devices. The usual physical activity level and socioeconomic status were considered confounding factors. Associations were determined using multivariate linear models with simultaneous adjustments for confounding variables. A statistical analysis indicated that fruit consumption was negatively related to the body mass index, regardless of the adjustment for SB domains. Red meat consumption was positively related to the body mass index, and fried food consumption was positively related to the waist-to-height ratio, regardless of the adjustment for SB domains. The consumption of fried food was positively associated with global and central adiposity after the adjustments for confounding factors and time spent on screen devices. We concluded that dietary habits are related to adiposity in adults. However, SB domains seem to influence the relationship between body adiposity and dietary habits, mainly regarding the consumption of fried foods.
- Association of Lipoprotein Subfractions With Atherosclerosis in the Baseline Sample of ELSA-Brasil Cohort Study - A Cross-Sectional Analysis(2023) TEBAR, William R.; MENEGHINI, Vandrize; GOULART, Alessandra C.; SANTOS, Itamar S.; SANTOS, Raul D.; BITTENCOURT, Marcio S.; GENEROSO, Giuliano; PEREIRA, Alexandre; BLAHA, Michael J.; JONES, Steven R.; TOTH, Peter P.; OTVOS, James D.; LOTUFO, Paulo A.; BENSENOR, Isabela M.
- Comparison of Quality of Life in Breast Cancer Survivors with and without Persistent Depressive Symptoms: A 12-Month Follow-Up Study(2023) RIBEIRO, F. E.; TEBAR, W. R.; FERRARI, G.; PALMA, M. R.; FREGONESI, C. E.; CALDEIRA, D. T.; SILVA, G. C. R.; VANDERLEI, L. C. M.; BERETTA, V. S.; CHRISTOFARO, D. G. D.Although breast cancer treatments reduce mortality, their adverse effects can increase depression which impacts one’s quality of life (QoL). Physical activity (PA) seems to improve the QoL of breast cancer survivors (BCS). However, an unanswered question is the influence of PA on the QoL in BCS with depressive symptoms. Thus, we analyzed the influence of PA on the QoL in BCS with persistent depressive symptoms during 12 months of follow-up. The sample included 70 female BCS. Depression and QoL domains (i.e., functional capacity, physical limitations, body pain, general health status, vitality, social and emotional aspects, and mental health) were assessed at baseline and follow-up periods by the Hospital Anxiety and Depression Scale and SF-36, respectively. Habitual PA was assessed by Baecke’s questionnaire. Our results indicate a prevalence of 17.1% of depressive symptoms. Non-depressives BCS improved their physical limitations and general health status domains over time, but there were no observed differences in depressive BCS. BCS with persistent depressive symptoms (baseline and follow-up) showed worse QoL scores than non-depressives in all domains, regardless of confounding factors. When adjusted for PA, the difference between BCS depressives and non-depressives lost its significance in the functional capacity domain. In conclusion, habitual PA practice positively influenced the functional capacity domain of the QoL in BCS.
- GlycA, but Not C-reactive Protein is Associated With Baseline Carotid Artery Plaque in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)(2023) TEBAR, William R.; MENEGHINI, Vandrize; GOULART, Alessandra C.; SANTOS, Itamar S.; SANTOS, Raul D.; BITTENCOURT, Marcio S.; GENEROSO, Giuliano; PEREIRA, Alexandre C.; BLAHA, Michael J.; JONES, Steven R.; TOTH, Peter P.; OTVOS, James D.; LOTUFO, Paulo A.; BENSENOR, Isabela M.
- Relationship Between Heart Rate Variability and Resting Heart Rate in Accordance with the Physical Activity Level of Children and Adolescents: A Cross-Sectional Study(2023) SARAIVA, Bruna Thamyres Ciccotti; VANDERLEI, Luiz Carlos Marques; TEBAR, William Rodrigues; SILVA, Gabriela Caroline Rodrigues da; SUETAKE, Vinicius Yukio Botelho; RITTI-DIAS, Raphael Mendes; CHRISTOFARO, Diego Giulliano Destro
- Sports practice, walking and biking are positively related to quality of life in adults: A cross-sectional study(2023) SILVA, Stefany Carolaine Bezerra; TEBAR, William Rodrigues; FERRARI, Gerson; LEMES, Italo Ribeiro; AGUILAR, Beatriz Anizia Santos; TEIXEIRA, Milena S.; MOTA, Jorge; RITTI-DIAS, Raphael Mendes; BERETTA, Victor Spiandor; CHRISTOFARO, Diego Giulliano DestroIntroduction: Physical activity (PA) has been associated with better quality of life (QoL). However, it is not clear whether this association is similar considering the different PA domains and independent of the intensity of PA practiced.Objective: To analyze the relationship between the time spent in PA in different domains [i.e., occupational, sports practice, walking and biking (through a combination of leisure and active transport)] and the QoL (i.e., physical functioning, role-physical, body pain, general health status, vitality, social functioning, role-emotional, and mental health) in adults.Methods: Two hundred and sixty-one adults with median age of 43.0 years (Interquartile range = 27.0-55.0 years) participated in this epidemiological study with a cross-sectional design. The sample included 261 adults QoL, PA domains, and PA intensities were assessed by the Short-Form Health Survey questionnaire (SF-36), the Baecke questionnaire, and using an accelerometer, respectively. Linear regressions adjusting for sex, age, socioeconomic status, body mass index, smoking status, alcohol consumption, and moderate to vigorous PA were used for analysis.Results: Occupational PA was negatively related to body pain domain of QoL (8 =-4.29; 95%CI =-7.27/-1.31). Sports practice was positively related to physical functioning (8 = 3.34 95%CI = 0.52/6.15), general health status (8 = 5.48; 95%CI = 2.20/8.76), vitality (8 = 5.39; 95%CI = 2.18/8.60), and mental health (8 = 3.47; 95%CI = 0.27/6.67) domains of QoL. Walking and biking were positively associated with vitality (8 = 4.48; 95%CI = 0.84/8.13) and mental health (8 = 4.21; 95%CI = 0.64/7.79) QoL domains.Conclusion: In conclusion, PA domains were associated with QoL differently. Regardless of PA intensity (measured objectively) and other factors, walking and biking were associated with indicators of mental health and vitality.
- Potential Determinants Are Associated With Thyroid Peroxidase Antibodies Titers in Men and Women Participants of the ELSA-Brasil Study(2023) MENEGHINI, Vandrize; TEBAR, William; SANTOS, Itamar S.; JANOVSKY, Carolina; LOTUFO, Paulo A.; GOULART, Alessandra C.; BENSENOR, Isabela M.
- Combined Association of Novel and Traditional Inflammatory Biomarkers With Carotid Artery Plaque: GlycA Versus C-Reactive Protein (ELSA-Brasil)(2023) TEBAR, William R.; MENEGHINI, Vandrize; GOULART, Alessandra C.; SANTOS, Itamar S.; SANTOS, Raul D.; BITTENCOURT, Marcio S.; GENEROSO, Giuliano; PEREIRA, Alexandre C.; BLAHA, Michael J.; JONES, Steven R.; TOTH, Peter P.; OTVOS, James; LOTUFO, Paulo A.; BENSENOR, Isabela M.Elevated levels of glycoprotein acetylation (GlycA) and C-reactive protein (CRP) have been associated with carotid artery plaque (CAP). However, it is not yet established if elevations in both inflammatory biomarkers provide incremental association with CAP. This study aimed evaluate the cross-sectional association of high CRP and GlycA with CAP at baseline participants from the ELSA-Brasil adult cohort. Participants with information on CRP, GlycA, and CAP with neither previous cardiovascular disease nor CRP >10 mg/ L were included. High GlycA and CRP were defined as values within upper quintile and >3 mg/L, respectively. Participants were classified into 4 groups: 1. nonelevated CRP/ GlycA (reference group); 2. elevated CRP alone; 3. elevated GlycA alone; and 4. both elevated. The analysis included 4,126 participants with median age of 50 years-old, being 54.2% of women. Prevalence of CAP was 36.1%. Participants with high CRP had the highest frequency of obesity, whereas participants with high GlycA presented higher cardiovascular risk factor burden and were more likely to have CAP than the reference group (odds ratio [OR] 1.39, 95% confidence interval [CI] 1.11 to 1.73), persisting after multivariable adjustment (OR 1.37, 95% CI 1.02 to 1.83). Participants with both elevated CRP and GlycA were more likely to have CAP in crude (OR 1.35, 95% CI 1.10 to 1.65) but not in adjusted models. The findings suggest potential different biologic pathways between inflammation and carotid atherosclerosis: high GlycA was associated with CAP whereas high CRP was more associated with obesity. & COPY; 2023 Elsevier Inc. All rights reserved. (Am J Cardiol 2023;204:140-150)
- Carotid intima-media thickness in adults with and without psoriasis - a nested case-control study from baseline data of ELSA-Brasil cohort(2023) TEBAR, William R.; SANTOS, Itamar de S.; MENEGHINI, Vandrize; BITTENCOURT, Marcio Sommer; LOTUFO, Paulo A.; BENSENOR, Isabela M.There is a lack of consensus about the association between psoriasis (PSO) and carotid intima-media thickness (cIMT) in literature, since previous studies considered dermatologic clinic patients or general population. This study aimed to compare cIMT levels according to PSO in a sample of 10,530 civil servants form the ELSA-Brasil cohort study and analyze its association with the disease. The PSO cases and disease duration were identified by medical diagnosis self-reported at study enrollment. A paired group was identified by propensity score matching among all the participants without PSO. Mean cIMT values were considered for continuous analysis while cIMT above 75th percentile was considered for categorical analysis. Multivariate conditional regression models were used to analyze association between cIMT and PSO diagnosis, by comparing PSO cases against paired controls and overall sample without disease. A total of n = 162 PSO cases were identified (1.54%) and no difference in cIMT values was observed between participants with PSO and overall sample or control group. PSO was not associated with linear increment of cIMT (vs. overall sample: beta = 0.003, p = 0.690; vs. matched controls: beta = 0.004, p = 0.633) neither with increased chance of having cIMT above 75th percentile (vs. overall sample: OR = 1.06, p = 0.777; vs. matched controls: OR = 1.19, p = 0.432; conditional regression: OR = 1.31, p = 0.254). There was no relationship between disease duration and cIMT (beta = 0.000, p = 0.627). Although no significant relationship between mild cases of psoriasis and cIMT was observed among a wide cohort of civil servants, longitudinal investigation about cIMT progression and severity of disease are still needed.
- Association between Leisure-Time and Commute Physical Activity and Pre-Diabetes and Diabetes in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)(2023) SANCHEZ-MARTINEZ, Yuri; GOULART, Alessandra C.; ALMEIDA-PITITTO, Bianca de; DUNCAN, Bruce B.; SCHMIDT, Maria Ines; SANTOS, Itamar de Souza; LOTUFO, Paulo A.; TEBAR, William R.; BENSENOR, Isabela M.Background: Diabetes is an important public health problem due to its health impairments and high costs for health services. We analyzed the relationship between the domains of physical activity at leisure-time (LTPA) and at commuting (CPA) with diabetes and pre-diabetes in an ELSA-Brasil study. Methods: Data from 11,797 participants (52.5% women, 49.1 +/- 7.2 years) were analyzed. LTPA and CPA were measured using the International Physical Activity Questionnaire. Diabetes and pre-diabetes were defined by medical history, medication use to treat diabetes or blood glucose. Logistic regression models were performed to estimate the association between LTPA and CPA with diabetes and pre-diabetes after adjustment for sociodemographic and cardiovascular risk factors. Results: The prevalence of LTPA and CPA was 24.4% and 34%, respectively. Physically active participants at LTPA were less likely to have pre-diabetes (OR = 0.86 [95% CI = 0.77-0.95]) and diabetes (OR = 0.80 [95% CI = 0.69-0.93]), compared with inactive participants. No association between CPA and diabetes/pre-diabetes was observed. LTPA was inversely associated with diabetes among men (OR = 0.73 [95% CI = 0.60-0.89]), but was not associated among women. Women who were active (OR = 0.78 [95% CI = 0.67-0.90]) (OR = 0.79 [95% CI = 0.65-0.95]) at LTPA were less likely to have pre-diabetes, than inactive women. Conclusion: LTPA was inversely associated with diabetes and pre-diabetes in the ELSA-Brasil participants. A different behavior was observed between genders.
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