NIVALDO ALONSO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cirurgia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/04 - Laboratório de Microcirurgia, Hospital das Clínicas, Faculdade de Medicina - Líder
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/04 - Laboratório de Microcirurgia, Hospital das Clínicas, Faculdade de Medicina - Líder
15 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 15
- Global Surgery 2030: Evidence and solutions for achieving health, welfare, and economic development(2015) MEARA, John G.; LEATHER, Andrew J. M.; HAGANDER, Lars; ALKIRE, Blake C.; ALONSO, Nivaldo; AMEH, Emmanuel A.; BICKLER, Stephen W.; CONTEH, Lesong; DARE, Anna J.; DAVIES, Justine; MERISIER, Eunice Derivois; EL-HALABI, Shenaaz; FARMER, Paul E.; GAWANDE, Atul; GULLIES, Rowan; GREENBERG, Sarah L. M.; GRIMES, Canis E.; GRUEN, Russell L.; ISMAIL, Edna Adan; KAMARA, Thaim Buya; LAVY, Chris; GANBOLD, Lundeg; MKANDAWIRE, Nyengo C.; RAYKAR, Nakul P.; RIESEL, Johanna N.; RODAS, Edgar; ROSE, John; ROY, Nobhojit; SHRIME, Mark G.; SULLIVAN, Richard; VERGUET, Stephane; WATTERS, David; WEISER, Thomas G.; WILSON, Iain H.; YAMEY, Gavin; YIP, Winnie
- Three-Dimensional Changes of Maxilla after Secondary Alveolar Cleft Repair: Differences Between rhBMP-2 and Autologous Iliac Crest Bone Grafting(2015) RAPOSO-AMARAL, Cassio Eduardo; DENADAI, Rafael; ALONSO, NivaldoBackground: Recombinant human bone morphogenetic protein (rhBMP)-2 has been used as an alternative to autologous bone transferring, a standard method of treatment. However, its potential adverse effect on anterior maxillary arch is unknown. Thus, the purpose of this study was to quantify sagittal and transversal changes of anterior maxilla after secondary alveolar cleft repair using traditional iliac crest bone grafting versus rhBMP-2. Methods: Twelve unilateral complete cleft lip and palate patients were randomly divided into 2 groups. In group 1, patients underwent traditional iliac crest bone grafting transferring (n = 4), and in group 2, patients underwent alveolar cleft reconstruction using collagen matrix with lyophilized rhBMP-2 (n = 8). Computed tomography (CT) imaging was performed preoperatively and at 1 year postoperatively, using a previously standardized protocol. A three-dimensional (3D) CT cephalometric analysis of the linear and angular measurements of the sagittal and transverse maxilla planes was performed to assess intra-and intergroup maxillary changes. Results: Intra-and intergroup comparisons of the pre-and postoperative 3D CT cephalometric linear and angular measurements of the sagittal and transverse maxilla planes showed no significant (all P > 0.05) differences among all studied variables. Conclusions: There were no significant anterior maxilla changes after maxillary cleft repair either using iliac crest bone grafting or rhBMP-2.
- Evaluation of oral-motor movements and facial mimic in patients with head and neck burns by a public service in Brazil(2015) MAGNANI, Dicarla Motta; SASSI, Fernanda Chiarion; VANA, Luiz Philipe Molina; ALONSO, Nivaldo; ANDRADE, Claudia Regina Furquim deOBJECTIVES: The purpose of this study was to analyze the characteristics of oral-motor movements and facial mimic in patients with head and neck burns. METHODS: An observational descriptive cross-sectional study was conducted with patients who suffered burns to the head and neck and who were referred to the Division of Orofacial Myology of a public hospital for assessment and rehabilitation. Only patients presenting deep partial-thickness and full-thickness burns to areas of the face and neck were included in the study. Patients underwent clinical assessment that involved an oral-motor evaluation, mandibular range of movement assessment, and facial mimic assessment. Patients were divided into two groups: G1 - patients with deep partial-thickness burns; G2 - patients with full-thickness burns. RESULTS: Our final study sample comprised 40 patients: G1 with 19 individuals and G2 with 21 individuals. The overall scores obtained in the clinical assessment of oral-motor organs indicated that patients with both second- and third-degree burns presented deficits related to posture, position and mobility of the oral-motor organs. Considering facial mimic, groups significantly differed when performing voluntary facial movements. Patients also presented limited maximal incisor opening. Deficits were greater for individuals in G2 in all assessments. CONCLUSION: Patients with head and neck burns present significant deficits related to posture, position and mobility of the oral myofunctional structures, including facial movements.
- Reduced Three-Dimensional Nasal Airway Volume in Treacher Collins Syndrome and Its Association with Craniofacial Morphology(2015) MA, Xiaoyang; FORTE, Antonio Jorge; BERLIN, Nicholas Lee; ALONSO, Nivaldo; PERSING, John A.; STEINBACHER, Dereck MatthewBackground: Airway insufficiency decreases quality of life and may be life threatening in patients with Treacher Collins syndrome. The authors calculated the three-dimensional nasal airway volume in patients with Treacher Collins syndrome to identify correlations between nasal airway volume and craniofacial morphology and provide guidance for surgical planning. Methods: Thirty nonoperated patients with Treacher Collins syndrome were compared with 35 unaffected age-and gender-matched controls. Anatomic variables of the cranial base, the maxilla complex, and internal diameters of nasal airway were compared between patients and control subjects using three-dimensional craniometric analyses. In the Treacher Collins group, the relation of craniofacial morphology to nasal airway volume was assessed separately. Statistical analyses were performed using independent sample t tests and Pearson correlation coefficient analyses. Results: Nasal airway volume was decreased 38.6 percent in patients with Treacher Collins syndrome relative to controls (p = 0.001). A positive correlation of maxillary position and nasal airway volume was shown in Treacher Collins patients (r = +0.463, p = 0.013). Maxillary, nasal bone, and orbitale width were also positively correlated with nasal airway volume (r = +0.582, p = 0.001; r = +0.408, p = 0.035; and r = +0.677, p < 0.001, respectively). Shortened internal diameters of the nasal airway all positively correlated with nasal airway volume. Conclusions: Nasal airway volume is reduced in patients with Treacher Collins syndrome. Reduced projection of the maxilla and transverse maxillary deficiency are correlated with reduced nasal airway volume and are primarily responsible for obstruction of the nasal airway.
bookPart Fissuras lábio palatais(2015) TANIKAWA, Daniela; ALONSO, Nivaldo- Pediatric Lip Replantation: A Case of Supermicrosurgical Venous Anastomosis(2015) BAPTISTA, Rachel Rossine; BARREIRO, Guilherme Cardinali; ALONSO, Nivaldo
- Rare Variants in the Epithelial Cadherin Gene Underlying the Genetic Etiology of Nonsyndromic Cleft Lip with or without Cleft Palate(2015) BRITO, Luciano Abreu; YAMAMOTO, Guilherme Lopes; MELO, Soraia; MALCHER, Carolina; FERREIRA, Simone Gomes; FIGUEIREDO, Joana; ALVIZI, Lucas; KOBAYASHI, Gerson Shigeru; NASLAVSKY, Michel Satya; ALONSO, Nivaldo; FELIX, Temis Maria; ZATZ, Mayana; SERUCA, Raquel; PASSOS-BUENO, Maria RitaNonsyndromic orofacial cleft (NSOFC) is a complex disease of still unclear genetic etiology. To investigate the contribution of rare epithelial cadherin (CDH1) gene variants to NSOFC, we target sequenced 221 probands. Candidate variants were evaluated via in vitro, in silico, or segregation analyses. Three probably pathogenic variants (c.760G>A [p.Asp254Asn], c.1023T>G [p.Tyr341*], and c.2351G>A [p.Arg784His]) segregated according to autosomal dominant inheritance in four nonsyndromic cleft lip with or without cleft palate (NSCL/P) families (Lod score: 5.8 at = 0; 47% penetrance). A fourth possibly pathogenic variant (c.387+5G>A) was also found, but further functional analyses are needed (overall prevalence of CDH1 candidate variants: 2%; 15.4% among familial cases). CDH1 mutational burden was higher among probands from familial cases when compared to that of controls (P = 0.002). We concluded that CDH1 contributes to NSCL/P with mainly rare, moderately penetrant variants, and CDH1 haploinsufficiency is the likely etiological mechanism.
- Complex nasal reconstruction after paracoccidioidomycosis infection - Case report(2015) RIBEIRO, Emilie Barreto; POCHAT, Victor Diniz de; MAGALDI, Eduarda Nilo de; FIGUEIREDO, Bruno Suffredini; ALONSO, Nivaldo; MENESES, Jose Valber de LimaParacoccidioidomycosis is an infectious disease whose etiological agent belongs to the Paracoccidioides genus. Although it affects primarily the lungs, it can spread to other tissues, including the skin and mucous membranes. Despite the clinical treatment for this disease, scarring can produce sequelae, manifesting as anatomical and functional deformities of the face. We present a case of extensive, nasal unaesthetic and functional sequelae resulting from paracoccidioidomycosis, reconstructed using the paramedian forehead flap in three stages, through the regional unit principles.
- Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development(2015) MEARA, John G.; LEATHER, Andrew J. M.; HAGANDER, Lars; ALKIRE, Blake C.; ALONSO, Nivaldo; AMEH, Emmanuel A.; BICKLER, Stephen W.; CONTEH, Lesong; DARE, Anna J.; DAVIES, Justine; MERISIER, Eunice Derivois; EL-HALABI, Shenaaz; FARMER, Paul E.; GAWANDE, Atul; GILLIES, Rowan; GREENBERG, Sarah L. M.; GRIMES, Caris E.; GRUEN, Russell L.; ISMAIL, Edna Adan; KAMARA, Thaim Buya; LAVY, Chris; LUNDEG, Ganbold; MKANDAWIRE, Nyengo C.; RAYKAR, Nakul P.; RIESEL, Johanna N.; RODAS, Edgar; ROSE, John; ROY, Nobhojit; SHRIME, Mark G.; SULLIVAN, Richard; VERGUET, Stephane; WATTERS, David; WEISER, Thomas G.; WILSON, Iain H.; YAMEY, Gavin; YIP, Winnie
bookPart Cranioestenose(2015) MATUSHITA, Hamilton; ALONSO, Nivaldo; CARDEAL, Daniel Dante; ANDRADE, Fernanda