DENISE FREDIANI BARBEIRO

(Fonte: Lattes)
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Departamento de Clínica Médica, Faculdade de Medicina
LIM/51 - Laboratório de Emergências Clínicas, Hospital das Clínicas, Faculdade de Medicina

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  • bookPart 1 Citação(ões) na Scopus
    Sepsis: Future role of omics in diagnosis and therapy
    (2019) BARBEIRO, H. V.; BARBEIRO, D. F.; SORIANO, F. G.
    Protocoled interventions for sepsis have dominated the guidelines of international societies. Treatment has to start quickly. In sepsis as in other emergencies, it has been demonstrated that time since emergency room admission and antibiotic prescription determine clinical evolution. Precision medicine-based sepsis management faces a specific problem. In addition to being accurate, diagnosis has to be fast. In a matter of hours, a patient may have died from an infection that has turned into sepsis. Techniques for proteomics, genomics, metabolomics, and all omics are indeed becoming more accurate and fast. Yet time to receive laboratory results is the limiting factor for implementing such advances in clinical practice. In this chapter we review recent data about omics, and how they can help for better diagnosis and treatment. © 2020 Elsevier Inc. All rights reserved.