MARCELO CALDERARO

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Instituto Central, Hospital das Clínicas, Faculdade de Medicina

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  • article 1 Citação(ões) na Scopus
    Vestibular migraine
    (2022) SILVA, Viviane Passarelli Ramin; CASTRO, Luiz Henrique Martins; CALDERARO, Marcelo
    Vestibular migraine (VM) remains an underdiagnosed condition, often mistaken with brainstem aura. VM is defined by recurrent vestibular symptoms in at least 50% of migraine attacks. Diagnosis is established by clinical criteria based on the International Classification of Headache Disorders (ICHD-3). Estimated prevalence of VM is 1 to 2.7% of the adult population.Vestibular symptoms usually appear after the headache. VM pathophysiology remains poorly understood. Vertigo may occur before, during, after the migraine attack, or even independently, and may last seconds to hours or days. Pathophysiological mechanisms for VM are still poorly understood and are usually extrapolated from migraines. Differential diagnoses include Meniere's disease, benign paroxysmal positional vertigo, brainstem aura, transient ischemic attack, persistent perceptual postural vertigo,and episodic type 2 ataxia. Specific treatment recommendations for vestibular migraine are still scarce.
  • article 23 Citação(ões) na Scopus
    Effect of a Quality Improvement Intervention on Adherence to Therapies for Patients With Acute Ischemic Stroke and Transient Ischemic Attack: A Cluster Randomized Clinical Trial
    (2019) MACHLINE-CARRION, M. Julia; SANTUCCI, Eliana Vieira; DAMIANI, Lucas Petri; BAHIT, M. Cecilia; MALAGA, German; PONTES-NETO, Octavio Marques; MARTINS, Sheila Cristina Ouriques; ZETOLA, Viviane Flumignan; NORMILIO-SILVA, Karina; FREITAS, Gabriel Rodrigues de; GORGULHO, Alessandra; CUNHA, Ricardo Santos; SANTOS, Aparecida Bernardes dos; FERREIRA, Luis Ley Gabriel; SAAD, Michele de Nardi; MACHADO, Michel Ferreira; LUNARDI, Camila; FERRAZ, Jamana Barbosa P.; OLIVEIRA, Pablo Nascimento; VICENTE, Suellen Mariane Rios; BETTGER, Janet Prvu; PAULA, Monica de; JEREMIAS, Maria da Conceicao; ROCHA, Fernanda Mota; IBIAPINA, Viviane de Sobral; ESMANHOTTO, Bruno Bertoli; KONDO, Erika; GOMES, Denilsen Carvalho; OLIVEIRA, Wellington Gondim de; LACERDA, Nair Gomes Soares; SILVA, Priscila Rodrigues e; ANDRADE, Marianna; FERREIRA, Natalia Cristina; LOPES, Renato D.; PEDREIRA, Arthur; ARAVENA, Tania Mariela Martinez; HASSELMANN, Rafaela Souza; SANTOS, Natalia Oliveira; GOES, Fernanda; PASSOS, Tissiana; PIRAS, Claudio; TALIULE, Aparecida; ZURRU, Maria Cristina; VALE, Solene Sousa; ALONZO, Claudia; PETERSON, Eric D.; BRESCACIN, Laura; GUIDO, Bibiana; CILENTI, Luciana; SENA, Luiz Rogerio; MOREIRA, Priscila Santos; GUSMAO, Rizia; CAVALCANTE, Liane; OLIVEIRA, Geane Borge de; KENNERLY, Silvia Eduara; OLIVEIRA, Andrea Guedes de; BACKSMANN, Alessandra; BERWANGER, Otavio; THEOTONIO, Joao Manoel; OSUGUE, Raphael Kazuo; GUERRA, Silvio; SILVA, Adriana Cruz Sarde da; CARVALHO, Paula Cristina Gonzaga; SANTOS, Edval Gomes dos; FARIAS, Tarsis Leonardo Almeida; AVELAR, Wagner Mauab; SANTOS, Anne Adrielle Oliveira; ALMEIDA FILHO, Alberto Cezar Santos; SOUZA, Felipe Ferreira Ribeiro de; MACHLINE-CARRION, Maria Julia; NUNES, Renata; CARVALHO, Mariana; GARCIA, Maria del Pilar Pozo; LIMA, Gonzalo; IOLI, Pablo Leonardo; GINEL, Malena; KOSLIK, Jessika Luana Alves; KLEIN, Francisco Ricardo; CLAVERIE, Carlos Santiago; CUOTO, Juan Blas Marcos; FRASQUETE, Analia; BERWANGER, Otavio; FERREIRA, Lis Campos; ALMEIDA, Andreza S.; SANTOS, Aline; ROCHA, Marcela; JURE, Lorena Vanina; KATSURAYAMA, Marilise; ESCHOYEZ, Maria Soledad; PEREIRA, Luiz Rogerio Sena; GUSMAO, Rizia Rocha Menezes; MOREIRA, Prisicla Santos; KUSTER, Gustavo Wruck; SANTUCCI, Eliana Vieira; MARTINS, Siderleny; MARTINS, Eliana Vieira do Nascimento; MALAGA, German; SORIANO, Victor Manuel Ortiz; SOUSA, Alessandro Augusto Viana e; ANGHINAH, Renato; NAKAJIMA, Karina; RUGGERO, Laisa Maia; RITT, Luiz Eduardo Fonteles; OLIVEIRA, Queila Borges de; CARRION, Mario Husek; DAMIANI, Lucas Petri; PAESE, Mari Ines; COSTA, Samanta da; GIACOMAZZI, Juliana; DONATTI, Amanda; NEUENSCHWANDER, Fernando Carvalho; MATOS, Arlete Pereira; NEUENSCHWANDER, Cristina; NETO, Ernesto Lippi; COSTA, Elisiany Mello; CASTILHO JUNIOR, Marco Antonio Mendes; TELES, Jose Mario Meira; BAHIT, Cecilia M.; ENDRIGO, Katia; COSTA, Ludmila Teodoro da; PAVANI, Pricila; MALAGA, German; NETO, Octavio Marques Pontes; ZETOLA, Viviane Flumignan; NORMILIO-SILVA, Karina; BETTGER, Janet Prvu; XIAN, Ying; LOPES, Renato Delascio; PETERSON, Eric; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; SALLES, Antonio De; BAHIT, M. Cecilia; MALAGA, German; MARTINS, Sheila Cristina Ouriques; NETO, Octavio Marques Pontes; ZETOLA, Viviane Flumignan; GUIMARAES, Helio Penna; CAVALCANTI, Alexandre Biasi; FREITAS, Gabriel Rodrigues de; SALLES, Antonio De; GORGULHO, Alessandra; CONFORTO, Adriana; XIAN, Ying; BETTGER, Janet Prvu; LOPES, Renato Delascio; PETERSON, Eric; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; GUIMARAES, Helio Penna; CAVALCANTI, Alexandre Biasi; MACHLINE-CARRION, Maria Julia; BAHIT, Cecilia M.; CALDERARO, Marcelo; MALAGA, German; MACHLINE-CARRION, Maria Julia; BERWANGER, Otavio; CAVALCANTI, Alexandre Biasi; LARANJEIRA, Ligia Nasi; SOARES, Rafael Marques; SILVA, Karina Normilio; BUENO, Priscila Regina; SANTUCCI, Eliana; CAMPOS, Viviane Bezerra; BULLA, Marina Lucia; RIBEIRO, Gisele Fialho Mota; GONZALES, Beatriz Pacheco; YAMASHITA, Juliana; KODAMA, Alessandra; SAMPAIO, Bruna; BARROS, Gabriel de Melo; CANDIDO, Carolina Trovarelli; JESUINO, Isabella de Andrade; ARBAIT, Tamiris; PINHEIRO, Samara; PARISOTO, Jaynne; BUSTA, Patricia; TEJADA, Virgina; DAMIANI, Lucas Petri; NAKAGAWA, Renato Hideo; BAHIT, Cecilia; ESNAOLA, Maria Marta; MALAGA, German; CABAJAL, Andre; BUSTA, Patricia; BAREA, Liselotte Menke; ANDRADE, Karina Nocelo Ferreiro de; SANTIM, Ricardo; DAMES, Jerusa; PARANHOS, Jorge Luiz da Rocha; LIMA, Gerluce Nery; MELO, Leonardo Vaz de; MARTINS, Sheila Cristina Ouriques; FLECK, Natacha; CAMARGO, Daiane Piccolotto Carvalho; OLIVEIRA, Fabiani Santos de; BRAGA, Gabriel Pereira; FREITAS, Paloma Fontes de; BAZAN, Rodrigo; ARANTES, Juliana; VIANA, Lorena Souza; ALQUERES, Rafaela; TRENTIN, Sheila; MORALES, Diego; SILVA, Beatriz Gonzales Pacheco da; FERNANDES, Maristela Thalheimer; VOIGT, Camila; MARTINS, Gladys Lentz; PAULI, Carla; ZETOLA, Viviane Flumignan; RASO, Larissa; RUBERT, Mauren Carneiro; SARAIVA, Sonia Batista; NOGUEIRA, Marcia Aparecida Camacho Kauffmann; MONTENARO, Kamilla Machado Paschoal; SANTOS, Juliana Yamashita; VELOSO, Cabo; MARTIN, Jose Fernando Vilela; BATTAGLINI, Mariana; PARISE, Viviane; BUTINHAO, Fernanda; MARTINELLI, Debora; ZANATTA, Joao Marcos de Menezes; RIBEIRO, Suzilene; TUNUCCI, Cileia Cristina Goncalves; CASTRO, Edna Donizete Rossi; JESUINO, Isabella de Andrade; DALL'ORTO, Frederico Toledo Campo; BERGO, Ricardo Reinaldo; RIBEIRO, Gislayne Rogante; SILVA, Gisele Sampaio; ALVES, Maramelia Araujo de Miranda; REGIS, Dalva; SILVA, Ilana Izidoro; SADALA, Danyelle; ROCHA, Felipe; ROCHA, Emilia Eva; BUENO, Priscila Regina Torres; ROUANET, Carolina; GALIARDI, Vivian; NARDOTO, Luiz Felipe; MERIDA, Kristel; BRAINER, Joao; RISCO, Eduardo Javier Tapia; TAHUA, Andre Aquiles Carbajal; BUSTA, Patricia; REYS, Michael; VELASQUEZ, Rafael Francisco; CAVALCANTI, Alexandre Biasi; CAHUARUPAY, Celia; CASTILLO, Diana; MONTES, Gerson Escobar; BARBOSA, Luiz Carlos Viana; VASCONCELOS, Jose Eduardo Gomes; CRUZ, Erica Maria Brandao; GONZALEZ, Leonardo Adrian; LEPERA, Sandra; PAEZ, Mauricio; MATIAS, Alet; GUIMARAES, Helio Penna; ALVA, Edwin Javier Pretell; ESNAOLA, Maria Martha; SCHIAVA, Marianela; TAGLIANI, Paula; REITERI, Romanela Carolina; GIARDINO, Daniela; EVARISTO, Eli; SANTOS, Edgar Ferreira dos; TAMBURIM, Barbara Reis; PEREIRA, Nathalia C. A.; XIAN, Ying; ROSA, Geiza Cristina Lozano Gomes da
    Key PointsQuestionCan a multifaceted quality improvement intervention increase the adherence to 10 evidence-based performance measures for patients with acute ischemic stroke and transient ischemic attack in Latin America? FindingsIn this cluster randomized clinical trial that included 1624 patients from 36 hospitals in 3 countries, hospitals in the intervention group had a composite adherence score of 85.3% for the evidence-based performance measures, and those in the control group had a score of 77.8%, a difference that was not statistically significant. In a planned secondary analysis, improvement in adherence to all 10 performance measures was greater in the intervention group than in the control group using an all-or-none approach for the outcome. MeaningIn this cohort of patients with acute ischemic stroke and transient ischemic attack, a multifaceted intervention did not demonstrate an overall improvement in adherence to evidence-based performance measures compared with standard of care, yet individual care elements improved. This cluster randomized clinical trial assesses the effect of a multifaceted quality improvement intervention compared with routine care on adherence to evidence-based therapy among patients with acute ischemic stroke and transient ischemic attack. ImportanceTranslating evidence into clinical practice in the management of acute ischemic stroke (AIS) and transient ischemic attack (TIA) is challenging, especially in low- and middle-income countries. ObjectiveTo assess the effect of a multifaceted quality improvement intervention on adherence to evidence-based therapies for care of patients with AIS and TIA. Design, Setting and ParticipantsThis 2-arm cluster-randomized clinical trial assessed 45 hospitals and 2336 patients with AIS and TIA for eligibility before randomization. Eligible hospitals were able to provide care for patients with AIS and TIA in Brazil, Argentina, and Peru. Recruitment started September 12, 2016, and ended February 26, 2018; follow-up ended June 29, 2018. Data were analyzed using the intention-to-treat principle. InterventionsThe multifaceted quality improvement intervention included case management, reminders, a roadmap and checklist for the therapeutic plan, educational materials, and periodic audit and feedback reports to each intervention cluster. Main Outcomes and MeasuresThe primary outcome was a composite adherence score for AIS and TIA performance measures. Secondary outcomes included an all-or-none composite end point of performance measures, the individual process measure components of the composite end points, and clinical outcomes at 90 days after admission (stroke recurrence, death, and disability measured by the modified Rankin scale). ResultsA total of 36 hospitals and 1624 patients underwent randomization. Nineteen hospitals were randomized to the quality improvement intervention and 17 to routine care. The overall mean (SD) age of patients enrolled in the study was 69.4 (13.5) years, and 913 (56.2%) were men. Overall mean (SD) composite adherence score for the 10 performance measures in the intervention group hospitals compared with control group hospitals was 85.3% (20.1%) vs 77.8% (18.4%) (mean difference, 4.2%; 95% CI, -3.8% to 12.2%). As a secondary end point, 402 of 817 patients (49.2%) at intervention hospitals received all the therapies that they were eligible for vs 203 of 807 (25.2%) in the control hospitals (odds ratio, 2.59; 95% CI, 1.22-5.53; P=.01). Conclusions and RelevanceA multifaceted quality improvement intervention did not result in a significant increase in composite adherence score for evidence-based therapies in patients with AIS or TIA. However, when using an all-or-none approach, the intervention resulted in improved adherence to evidence-based therapies. Trial RegistrationClinicalTrials.gov identifier: NCT02223273
  • bookPart
    Novas Tecnologias em Comunicação Médica
    (2016) CALDERARO, Marcelo
  • conferenceObject
    Recurrent visits to the Emergency Department (ED) due to Headache: economic burden and epidemiological profile
    (2019) SOUZA, Marcio Nattan P.; CALDERARO, Marcelo; OLIVEIRA, Ana Paula D. S.; KUBOTA, Gabriel T.; ZAMBON, Lucas S.; ANGHINAH, Renato; JORDAO, Mauricio R.
  • conferenceObject
    Profile of migraine investigation in the emergency department of a tertiary hospital in Brazil: the exceeding use of Brain CT
    (2021) SOUZA, M. N.; KUBOTA, G.; FONSECA, A. P.; CALDERARO, M.; KUSTER, G.; JORDAO, M.; CARVALHO, R.; OLIVEIRA, A. P.; PINCERATO, R.
  • bookPart
    Delirium
    (2013) GUARNIERO, Francisco Bevilacqua; KAMITSUJI, Carla Satie; CALDERARO, Marcelo; WANG, Yuan-Pang; MARTINS, Herlon Saraiva; SANTOS, Franklin Santana
  • bookPart
    Coma e rebaixamento do nível de consciência
    (2013) CALDERARO, Marcelo; RABELLO, Getúlio Daré
  • conferenceObject
    Online survey revealing patients' journey throughout the Brazilian healthcare system
    (2021) SOUZA, M. N.; KUBOTA, G.; SIMIONI, C.; CALDERARO, M.; MATTOS, B.; CHAVES, L.; COSTA, B.; SANTOS, F. R.; PASSARELLI, V.; FORTINI, I.
  • bookPart
    Urgências Neurológicas
    (2015) FORTINI, Ida; PEREIRA, Cristiana Borges; CALDERARO, Marcelo
  • bookPart
    Coma e outras alterações da consciência
    (2021) STUDART NETO, Adalberto; CALDERARO, Marcelo; COMERLATTI, Luiz Roberto; CASTRO, Luiz Henrique Martins