MAURO RAZUK FILHO
Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
8 resultados
Resultados de Busca
Agora exibindo 1 - 8 de 8
conferenceObject The Use of Intraoperative Ecmo in Lung Transplantation: A Retrospective Analysis from the Largest Lung Transplant Center in Brazil(2023) SANTOS, S. dos; RAZUK FILHO, M.; POLA, F.; ABDALLA, L. G.; FERNANDES, L. M.; PEGO-FEMANDES, P.- Risk factors related to pleural empyema after talc slurry pleurodesis(2022) D'AMBROSIO, Paula Duarte; ARAUJO, Pedro Henrique Xavier Nabuco de; ROCHA JUNIOR, Eserval; RAZUK FILHO, Mauro; PEGO-FERNANDES, Paulo Manuel; TERRA, Ricardo MingariniObjective: Empyema is a complication of talc-pleurodesis that may lead to further surgical intervention and death. Therefore, the present study's objective was to identify the risk factors for the development of post-pleurodesis empyema after talc slurry pleurodesis in order to better select patients for this procedure and minimize its morbidity.Methods: Patients with malignant pleural effusion who underwent talc slurry pleurodesis at the present institution from January 2018 to January 2020 were retrospectively analyzed. Post-pleurodesis empyema was defined as pleural infection up to 30 days after pleurodesis. Using Cox regression analysis, significant prognostic factors for the development of empyema were examined.Results: Of the 86 patients identified for inclusion in the study, 62 were women (72%). Their mean age was 56.3 +/- 12.6 years. The median pleural drainage time was 9 days, and 20 patients (23.3%) developed empy-ema. In the univariate analysis, both drainage time (p = 0.038) and the use of antibiotics prior to pleurodesis (p < 0.001) were risk factors for pleural empyema. Multivariate analysis also identified the use of antibiotics as an independent risk factor (Odds Ratio [OR] 9.81; 95% Confidence Interval [95% CI] 2.87-33.54). Although the pulmonary expansion was not associated with empyema in the multivariate analysis, patients with less than 50% pulmonary expansion had a 4.5-times increased risk of empyema (95% CI 0.90-22.86; p = 0.067), and patients with 50-70% pulmonary expansion had a 3.8-times increased risk of empyema (95% CI 0.98-15; p = 0.053) after pleurodesis.Conclusion: The study suggests that antibiotic therapy prior to talc slurry pleurodesis may increase the risk of developing empyema. Furthermore, pleurodesis should be considered with caution in patients with long-duration chest tube placement and incomplete lung expansion.
conferenceObject Cryobiopsy in the Diagnosis of Lung Allograft Rejection: Brazilian Case Series(2022) BELON, Carlos E. F.; OKUNO, Elissa A.; CAMPOS, Silvia V.; RODRIGUES, Ascedio J.; LIMA, Evelisse; SCORDAMAGLIO, Paulo R.; CAMARGO, Priscila C. L. B.; TEIXEIRA, Ricardo H. O. B.; CARRARO, Rafael M.; COSTA, Andre N.; PIRES, Juliana P.; REIS, Flavio P.; FERNANDES, Lucas M.; ABDALLA, Luis G.; FERNANDES, Paulo M. P.; FILHO, Mauro R.; SANTOS, Samuel L.conferenceObject How to Do It: Use of Octopus Tissue Stabilizer for Minimal Manipulation Approach of the Bronchial Anastomosis in Lung Transplant(2022) RAZUK FILHO, Mauro; SANTOS, Samuel L. Dos; REIS, Flavio P. Dos; ABDALLA, Luis Gustavo; FERNANDES, Lucas M.; PEGO-FERNANDES, Paulo M.- COVID-19: Impact on Lung Transplant Activity at a Large Brazilian Hospital(2022) RAZUK FILHO, M.; FERNANDES, L. M.; PêGO-FERNANDES, P. M.
- Pneumomediastinum in COVID-19 disease: Outcomes and relation to the Macklin effect(2021) BRITO, Joao; GREGORIO, Paulo; MARIANI, Alessandro; D'AMBROSIO, Paula; FILHO, Mauro; FERREIRA, Lorena; SAWAMURA, Marcio; PEGO-FERNANDES, Paulo ManuelAim Pneumomediastinum (PM) is associated with several etiologies and mechanisms. Although it has been described more than 100 years ago, the literature is limited to small retrospective studies. This study aimed to follow patients with coronavirus disease (COVID-19) that developed PM during hospitalization and describe their clinical and radiological evolution. Methods A prospective cohort was developed with patients with PM, excluding those with aerodigestive trauma, inside a hospital COVID-19 dedicated hospital. Clinical variables including onset of symptoms, hemodynamic instability, associated complications, the need of interventions, and disease course were all recorded. Also, radiological findings such as the presence of the Macklin effect, extension of lung involvement by COVID-19, and characteristics of the PM were analyzed. Results Twenty-one patients with non-traumatic PM were followed, resulting in an overall incidence of 0.5% during the study period. Seven (33%) patients had associated pneumothorax and malignant/tension PM was observed in three (14%) cases. The Macklin effect could be found in 11 patients (52%) and the majority of them had more than 50% of lung involvement due to COVID-19. The mortality rate was 49%; however, no deaths were directly related to the PM. Conclusions PM incidence is probably increased in the severe acute respiratory syndrome caused by COVID-19, especially in those with greater involvement of the lungs, and the Macklin effect may be an important underlying mechanism of this complication. Usually, PM has a benign course, but complications like tension/malignant PM may occur requiring prompt detection and intervention.
conferenceObject The Use of ECMO in Lung Transplant and hybrid Cannulation: 10 Years of a Single Center Experience(2022) SANTOS, Samuel; RAZUK, Mauro; POLA, Flavio; NAKAHIRA, Evelyn; ABDALLA, Luis G.; FERNANDES, Lucas M.; PEGO-FERNANDES, Paulo M.- Use of OctopusTM Tissue Stabilizer for Minimal Manipulation Approach of Bronchial Anastomosis in Lung Transplant(2023) RAZUK FILHO, Mauro; SANTOS, Samuel Lucas dos; REIS, Flavio Pola dos; ABDALLA, Luis Gustavo; FERNADES, Lucas Matos; PEGO-FERNANDES, Paulo ManuelBronchial anastomotic complications are a cause of grave concern for surgeons that perform lung transplantations. There are several risk factors that may lead to this complication, being inadequate surgical technique one of them, specifically regarding adequate exposure and manipulation of the bronchial stump and anastomosis. Here we report the use of OctopusTM Tissue Stabilizer as a mean to allow for a better exposure of the stump and facilitate a ""no-touch"" approach towards anastomosis. Systematic application of devices that facilitate the employment of the correct surgical techniques can have an effect in reducing the incidence of bronchial anastomotic complications.