ROMULO DOS SANTOS SOBREIRA NUNES
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject CORRELATION BETWEEN LIBIDO AND TESTOSTERONE: ESTRADIOL RATIO IN MEN WITH SEXUAL DYSFUNCTION(2023) NETO, R. Pedrenho; NASCIMENTO, B. Chiesa Gouveia; NUNES, R. Dos Santos Sobreira; GISMONDI, J. Pedro; BESSA JR., J. De; NAHAS, W. Carlos; HALLAK, J.- Laparoscopic Ureterocalicostomy Technique(2023) NUNES, Romulo S. S.; SUARTZ, Caio V.; ANDRADE, Hiury S.; JORDAO, Ricardo D.; SROUGI, Victor; MITRE, Anuar I.; NAHAS, William C.; ARAP, Marco A.Purpose: Ureterocalicostomy is a technique that was first described by Neuwirt in 1948 (1) The laparoscopic access was initiated in 2003 by Cherullo et al. (2), following the established principles of open surgery. In 2004, Gill et al. had two patients with UPJO treated with laparoscopic ureterocalicostomy, with success (3). In 2014, Arap et. al. presented a case series with good results in adults and children in our service (4). There are factors that prepare the surgeon for an ureterocalicostomy, such as the renal cortex thickness, although the decision is mainly taken during the procedure (5).Material and Methods: A 24 years-old female patient with right lumbar pain was referred to our institution. She already had a right open pyeloplasty two years ago. The CT scan presented a right hydronephrotic kidney, DMSA scan with 30% of relative function and a DTPA scan with an obstructive pattern.Results: A laparoscopic ureterocalicostomy was performed due to the intra-operative findings (inferior kidney pole thickness and challenging access to the uretero-pelvic junction). The overall time was 130 minutes with no complications. The patient was discharged in two days and the double J was withdrawn in four weeks. The CT scan within one year demonstrates a reduction of the hydronephrosis. She had no more lumbar pain.Conclusion: In complex cases, the laparoscopic ureterocalicostomy proves to be a safe and efficient procedure, with a free tension-free anastomosis and the advantages of the laparoscopic access.
- Post-analysis methods for lactate threshold depend on training intensity and aerobic capacity in runners. An experimental laboratory study(2016) FERNANDES, Tiago Lazzaretti; NUNES, Romulo dos Santos Sobreira; ABAD, Cesar Cavinato Cal; SILVA, Andrea Clemente Baptista; SOUZA, Larissa Silva; SILVA, Paulo Roberto Santos; ALBUQUERQUE, Cyro; IRIGOYEN, Maria Claudia; HERNANDEZ, Arnaldo JoseCONTEXT AND OBJECTIVE: This study aimed to evaluate different mathematical post-analysis methods of determining lactate threshold in highly and lowly trained endurance runners. DESIGN AND SETTING: Experimental laboratory study, in a tertiary-level public university hospital. METHOD: Twenty-seven male endurance runners were divided into two training load groups: lowly trained (frequency < 4 times per week, < 6 consecutive months, training velocity >= 5.0 min/km) and highly trained (frequency >= 4 times per week, >= 6 consecutive months, training velocity < 5.0 min/km). The subjects performed an incremental treadmill protocol, with 1 km/h increases at each subsequent 4-minute stage. Fingerprint blood-lactate analysis was performed at the end of each stage. The lactate threshold (i.e. the running velocity at which blood lactate levels began to exponentially increase) was measured using three different methods: increase in blood lactate of 1 mmol/l at stages (DT1), absolute 4 mmol/l blood lactate concentration (4 mmol), and the semi-log method (semi-log). ANOVA was used to compare different lactate threshold methods and training groups. RESULTS: Highly trained athletes showed significantly greater lactate thresholds than lowly trained runners, regardless of the calculation method used. When all the subject data were combined, DT1 and semi-log were not different, while 4 mmol was significantly lower than the other two methods. These same trends were observed when comparing lactate threshold methods in the lowly trained group. However, 4 mmol was only significantly lower than DT1 in the highly trained group. CONCLUSION: The 4 mmol protocol did not show lactate threshold measurements comparable with DT1 and semi-log protocols among lowly trained athletes.
conferenceObject CORRELATION BETWEEN LIBIDO AND TESTOSTERONE: ESTRADIOL RATIO IN MEN WITH SEXUAL DYSFUNCTION(2022) PEDRENHO NETO, R.; NUNES, R. dos Santos Sobreira; NASCIMENTO, C. G. B.; BARBOSA NETO, C. Machado; BESSA JUNIOR, J. de; SROUGI, M.; NAHAS, W. CarlosconferenceObject Role of Dicer on human melanoma progression and resistance.(2018) VICTO, Nathalia Cruz de; ADJEMIAN, Sandy; NUNES, Romulo dos Santos Sobreira; VOLPINI, Rildo Aparecido; GIAVINA-BIANCHI, Mara Huffenbaecher; FESTA NETO, Cyro; CAMARA, Niels Olsen Saraiva; AMARANTE-MENDES, Gustavo Pessini; JACYSYN, Jacqueline de Fatima