FABIO FERNANDES MORATO CASTRO
Projetos de Pesquisa
Unidades Organizacionais
FM, Faculdade de Medicina
Departamento de Clínica Médica, Faculdade de Medicina - Docente
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina - Líder
Departamento de Clínica Médica, Faculdade de Medicina - Docente
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina - Líder
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Sensitization to cat allergen and its association with respiratory allergies: cross-sectional study(2017) GALVAO, Clovis Eduardo Santos; GRAUDENZ, Gustavo Silveira; KALIL, Jorge; CASTRO, Fabio Fernandes MoratoCats are a significant source of allergens that contribute towards worsening of allergic diseases. The aim of this study was to investigate the association between sensitization to cat allergens and allergic respiratory diseases. This was an observational retrospective study based on the skin prick tests results of patients at a tertiary-level hospital in Sao Paulo. A total of 1,985 test results were assessed. The prevalence of sensitization to cat allergen was 20% (399 patients). Our data indicated that in this population of atopic patients, a positive skin prick test result for cat allergen was not associated significantly with a diagnosis of respiratory allergy.
conferenceObject Inflammatory cell response, functional and biochemical features of the airways of professional cleaning workers upon exposure in the workplace(2017) LIMA, Cynthia F. Mafra; SARAIVA, Beatriz M.; KALIL, Jorge; CASTRO, Fabio M.; GALVAO, Clovis Eduardo S.conferenceObject Safety to Extensively Heated Cow's Milk Challenge in Children with Severe Cow's Milk Allergy(2017) CORDOVA, Pablo Torres; PEDROSO, Natalia Falci; MELLO, Marcella Fonseca; SALLES-CUNHA, Patricia; KALIL, Jorge; CASTRO, Fabio M.; YANG, Ariana CamposconferenceObject Local production of IgE and other immune mediators in the nasal lavage fluid of allergic rhinitis patients before and after specific immunotherapy with Dermatophagoides pteronyssinus(2017) TEIXEIRA, Adriana Rodrigues; SARAIVA, Beatriz M.; KALIL, Jorge; CASTRO, Fabio M.; GALVAO, Clovis Eduardo S.conferenceObject Severity profile of cow milk protein allergy IgE mediated(2017) ANAGUSKO, Claudia Leiko Yonekura; LOPES, Mariele Morandin; CAU, Larissa Prando; MARQUES, Paula Quadros; SALLES, Pamella Diogo; CASTRO, Fabio M.; KALIL, Jorge; YANG, Ariana CamposconferenceObject A Case Report of a Novel Compound Heterozygous Mutation in a Brazilian Patient with Deficiency of IL1RA (DIRA)(2017) MENDONCA, L. O.; GROSSI, A.; CORDOVA, P. Torres; AMORIM, L. C.; KALIL, J.; CASTRO, F. M.; PONTILLO, A.; CECCHERINI, I.; GATTORNO, M.; BARROS, M. T. Toledo- Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies(2017) GAGETE, Elaine; SANTOS, Lucilene Delazari dos; PONTES, Leticia Gomes de; CASTRO, Fabio MoratoBackground: The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures to avoid this type of allergic reaction. Aiming this objective, we validated an instrument for a population-basedstudy that assesses the prevalence of anaphylaxis in the Brazilian population. Methods: A questionnaire was generated in two variants - one for subjects seven years old or above (Group A) and another for children who were up to six years, 11 months and 29 days (Group B). The instrument was administered to patients with and without anaphylaxis. By allocating points, a score was calculated to differentiate subjects with and without the disease. After validation, the questionnaire was applied in the city of Botucatu (Sao Paulo state, Brazil), by randomly selecting houses and inviting residents to answer the questionnaire. Results: The questionnaire was reliable for identifying subjects with and without anaphylaxis in both groups, with a specificity and sensitivity above 90%. The prevalence of anaphylaxis in the pilot survey was 6.2% in Group A, however the evaluation was compromised in Group B by the low number of children below seven years of age due to random sampling of residences. Discussion: The prevalence of anaphylaxis in our pilot test (6.2%) was similar to major epidemiological surveys from several parts of the world, showing that anaphylaxis is not a rare disease. The instrument of the present work was suitable for this epidemiological survey and might be a good option for studying anaphylaxis in other populations. Conclusion: This instrument might be of particular value in places where researchers cannot access medical records to conduct similar epidemiological studies.