EDNA MARIA DE ALBUQUERQUE DINIZ
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Pediatria, Faculdade de Medicina - Docente
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
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bookPart Infecção gonocócica do recém-nascido(2022) VARGAS, Nádia Sandra Orozco; DINIZ, Edna Maria de AlbuquerquebookPart Pneumonias no recém-nascido(2022) KERNBICHLER, Euler João; DINIZ, Edna Maria de AlbuquerquebookPart Erros inatos do metabolismo(2022) OKADA, Giselle Garcia Origo; DINIZ, Edna Maria de AlbuquerquebookPart Displasia broncopulmonar(2022) CIANCIARULLO, Marco Antônio; DINIZ, Edna Maria de Albuquerque- Nonthyroidal illnesses syndrome in full-term newborns with sepsis(2015) SILVA, Maria Helena Baptista Nunes da; ARAUJO, Maria Cristina Korbage de; DINIZ, Edna Maria de Albuquerque; CECCON, Maria Esther Jurfest Rivero; CARVALHO, Werther Brunow deABSTRACT Objective To assess hormonal changes in nonthyroidal illness syndrome (NTIS) in full-term newborns (NT) with sepsis. Materials and methods We included 28 NT with sepsis divided into 2 groups according to the time of normalization of serum and clinical indicators of infection: group A(A), 16 NT with improvement in up to 8 days; and group B(B), 12 NT improvement after 8 days. Among the 28 NT, 15 NT progressed to septic shock, with 5 NT group A and 10 NT in group B. NT were excluded when they showed severe sepsis and asphyxia, and congenital malformations, as well as those whose mothers had thyroid disease and IUGR. Results 17 NT (60.7%) presented NTIS. Low T3 was observed in NTIS in 10 NT (58.8%), and low T4 and T3 in 5 NT (29.5%), all of them with septic shock. Two NT showed mixed changes (11.7%). After sepsis was cured, there was no hormonal change, except in 3 NT. Administration of dopamine, furosemide, and corticosteroids did not affect the results. Conclusions This study indicates that nonthyroidal illness syndrome may be transiently present during sepsis in full-term newborns, especially in cases of prolonged sepsis. Low T3 can occur without changes in reverse T3 (different from adults), and low T4 and T3 occur mainly in patients with septic shock. Arch Endocrinol Metab. 2015;59(6):528-34
bookPart Hipertensão pulmonar persistente neonatal(2022) CECCON, Maria Esther Jurfest Rivero; DINIZ, Edna Maria de AlbuquerquebookPart Infecção congênita pelo citomegalovírus(2022) DINIZ, Edna Maria de AlbuquerquebookPart Doença de Chagas congênita(2022) DINIZ, Edna Maria de Albuquerque; VARGAS, Nadia Sandra OrozcobookPart Síndrome de aspiração meconial(2022) DINIZ, Edna Maria de Albuquerque; CIANCIARULLO, Marco Antônio; CECCON, Maria Esther Jurfest RiverobookPart Sífilis congênita(2022) YOSHIMOTO, Cristina Erico; OKADA, Giselle Garcia Origo; DINIZ, Edna Maria de Albuquerque