MIGUEL LUIZ ANTONIO MODOLIN

Índice h a partir de 2011
6
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico

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Agora exibindo 1 - 3 de 3
  • article 3 Citação(ões) na Scopus
    Interference of silicone breast implants on bioimpedance measurement of body fat
    (2012) YAMAGUCHI, Camila M.; FAINTUCH, Joel; SILVA, Maira M.; MODOLIN, M.; HAYASHI, Silvia Y.; CECCONELLO, I.
    Background: No study targeting the impact of silicone breast implants on body composition measured by bioimpedance analysis was identified. Objective: Aiming to clarify this question a prospective clinical study was designed. Methods: Adult candidates were submitted to conventional analysis at baseline and two months after the surgical intervention. In addition, unwrapped prostheses were positioned in the axillary cavity before operation and bioimpedance was measured, both with and without application of ultrasound gel for improved conductivity (sham implantation). Results: Patients (N = 20) were young and healthy (26.8 +/- 3.6 years old, BMI 22.1 +/- 3.7 kg/m(2)). In comparison with preoperative results, sham procedures pointed out increased body fat and body resistance (13.2 +/- 5.6 vs 13.6 +/- 5.4 kg, P = 0.017 and 523 +/- 54 vs 569 +/- 53 Omega, P = 0.003, respectively). Two-month follow-up confirmed the same pattern after surgical intervention, with minor discrepancies (13.2 +/- 5.6 vs 13.8 +/- 5.7 kg, P = 0.011 and 523 +/- 54 vs 549 +/- 62 Omega, P = 0.032, respectively). BMI remained stable and did not correlate with bioimpedance changes. Conclusions: Silicone was recognized as adipose tissue. Difference in total body fat (approximately 600 g) was consistent with used amount.
  • article 14 Citação(ões) na Scopus
    Systemic Inflammatory Reaction After Silicone Breast Implant
    (2011) SILVA, Maira M.; MODOLIN, Miguel; FAINTUCH, Joel; YAMAGUCHI, Camila M.; ZANDONA, Cintia B.; CINTRA JR., Wilson; FUJIWARA, Haroldo; CURI, Rui; GEMPERLI, Rolf; FERREIRA, Marcos C.
    Systemic inflammation after augmentation mammaplasty with modern silicone implants is not currently recognized. In a prospective controlled study, C-reactive protein and other variables were monitored, aiming to test this hypothesis in a young cohort of patients. Females (18-30 years old, BMI = 18.5-30 kg/m(2), N = 52) were consecutively recruited for breast implant (n = 24, Group I) and for abdominal liposuction (n = 28, Group II/Controls). Patients were interviewed at baseline and followed until 6 months after operation. Variables included demographic and clinical information, surgical outcome, inflammatory markers and autoantibodies. Operations were well tolerated, without surgical or infectious complications. Mean prosthesis size was 258 +/- A 21 ml (range = 220-280) and mean aspirate of liposuction was 1972 +/- A 499 ml (range = 1200-3000). Preoperative, 2-month, and 6-month C-reactive protein concentrations for breast implant patients were 1.3 +/- A 1.2, 4.8 +/- A 3.0, and 4.3 +/- A 6.4 mg/l and for liposuction 3.5 +/- A 2.7, 3.5 +/- A 2.1, and 2.2 +/- A 2.2 mg/l, respectively. Change at 2 months was significant (p = 0.001). Autoantibody investigation failed to reveal remarkable aberrations, except for anticardiolipin elevation, which was nearly symmetrical in the two groups. C-reactive protein levels increased after operation and correlated with proinflammatory and procoagulatory indices. A mild increase in anticardiolipin IgM occurred but differences between populations were lacking. Despite excellent cosmetic outcomes and lack of complications, acute phase reaction could signal ongoing immunogenicity of silicone and long-term monitoring is recommended.
  • article 12 Citação(ões) na Scopus
    Monsplasty for Women After Massive Weight Loss
    (2012) MARQUES, Maira; MODOLIN, Miguel; CINTRA, Wilson; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    Ptosis with excess skin in the pubic area is a very common deformity in patients after massive weight loss. This deformity requires adequate surgical treatment whether combined with abdominoplasty or not. The enlarged pubogenital area may lead to psychosocial distress and impaired quality of life. A series of 23 women with a mean age of 39.5 years who previously underwent bariatric surgeries and later presented with pubogenital ptosis underwent monsplasty. The preoperative surgical markings and the surgical technique presented are easily reproducible. In this prospective study, the surgical outcomes were assessed by questionnaires applied to the patients, who scored the following parameters: movement dynamics, aesthetic appearance, sexual performance, improved hygiene, and use of clothing items. Four of the parameters assessed (movement dynamics, aesthetic appearance, hygiene, and use of clothing items) showed clear improvement, with scores ranging from good to very good. A small percentage of the patients (13%) reported fair improvement in sexual performance. The findings showed monsplasty to be a simple and reproducible technique with favorable outcomes and low morbidity rates.