HENRIQUE SILVA BOMBANA
Projetos de Pesquisa
Unidades Organizacionais
IPER, Hospital das Clínicas, Faculdade de Medicina
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina
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- Drink driving and speeding in Sao Paulo, Brazil: empirical cross-sectional study (2015-2018)(2019) ANDREUCCETTI, Gabriel; LEYTON, Vilma; CARVALHO, Heraclito Barbosa; SINAGAWA, Daniele M.; BOMBANA, Henrique S.; PONCE, Julio C.; ALLEN, Katharine A.; VECINO-ORTIZ, Andres I.; HYDER, Adnan A.Objectives To evaluate the prevalence of drink driving and speeding during 2015-2018 in Sao Paulo, Brazil. Design Cross-sectional observational study. Setting Roads representing the five main regions of the city of Sao Paulo in Brazil, one of the world's largest urban areas. Participants Drivers (N=10294) stopped at routine roadside breath testing checkpoints and those driving in selected roads for speeding measurement (N=414664). Primary and secondary outcome measures Microwave radar guns were used to measure the speed of vehicles, while the prevalence of drivers under the influence of alcohol was observed in police checkpoints. Data were collected during three consecutive years (2016-2018) following a baseline study established in 2015 using a city-level representative sample of observational data representing all days of the week. Results Alcohol-related fatalities kept at a constantly high percentage, with 39% of road traffic deaths involving alcohol in 2016. Drivers testing above the legal breath alcohol concentration limit showed a decreasing trend, from 4.1% (95% CI 2.9% to 5.5%) at baseline to 0.6% (95% CI 0.2% to 1.2%) in the end of 2018 (p<0.001); however, more than half of drivers refused breath tests at checkpoints despite steep legal penalties. The prevalence of speeding among all vehicles decreased from 8.1% (95% CI 7.9% to 8.2%) to 4.9% (95% CI 4.7% to 5.1%) by the end of 2016 (p<0.001), but then increased again to 13.5% (95% CI 13.2% to 13.9%) at the end of the study period (p<0.001). Conclusions Drink driving rates have reduced, likely due to an increase in drivers refusing breath alcohol tests, while speeding rates have increased significantly by the end of the study period, particularly among motorcycles. Future strategies aiming at reducing road traffic injuries in the major Brazilian city should tailor drink driving and speeding enforcement based on the new evidence provided here.
- Trends in the use of psychoactive substances by truck drivers in SAo Paulo State, Brazil: A time-series cross sectional roadside survey (2009-2016)(2019) LEYTON, Vilma; BOMBANA, Henrique Silva; MAGALHAES, Juliana Gallottini; PANIZZA, Helena Nascimento; SINAGAWA, Daniele Mayumi; TAKITANE, Juliana; CARVALHO, Heraclito Barbosa de; ANDREUCCETTI, Gabriel; YONAMINE, Mauricio; GJERDE, Hallvard; MUNOZ, Daniel RomeroObjective: Truck drivers represent a group that is susceptible to the use of stimulant substances to reduce the symptoms of fatigue, which may be caused by a stressful and exhausting work environment. The use of psychoactive substances may increase the risk for involvement in road traffic crashes. Previous studies have demonstrated that amphetamine, cocaine, and cannabis are the 3 main drugs used by Brazilian truck drivers. We studied the prevalence of amphetamine, benzoylecgonine (indicating use of cocaine), and -9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH; indicating use of cannabis) in urine samples from truck drivers in the state of SAo Paulo, Brazil, using the same methodology during 8 years (2009-2016).Methods: Samples were collected during a health program supported by the Federal Highway Police. Toxicological analyses were performed using immunoassays and gas chromatography-mass spectrometry.Results: The total prevalence of illicit drugs was 7.8%. Benzoylecgonine was the most prevalent substance (3.6%), followed by amphetamine (3.4%) and THC-COOH (1.6%). We found the highest drug prevalence in 2010 (11.3%) and the lowest in 2011 (6.1%). We could detect a slight change in the pattern of stimulant use: until 2010, amphetamine was the most prevalent substance; however, in 2011 benzoylecgonine became the most frequently detected substance. This lasted until 2015, probably due to changes in Brazilian legislation regarding appetite suppressants; the most common one is metabolized to amphetamine.Conclusion: These data show that the use of psychoactive substances by truck drivers in Brazil did not decrease during the study period. This reinforces the need for further preventive measures to reduce drug use among drivers, which could lead to a decrease in traffic crashes in Brazil.
- HAIR TESTING: AN INEFFECTIVE DUI STRATEGY IN BRAZIL(2018) LEYTON, Vilma; ANDREUCCETTI, Gabriel; MEIRA JUNIOR, Antonio Edson Souza; SANTOS, Marcelo Filonzi Dos; BOMBANA, Henrique Silva; WALLS, H. Chip; GREVE, Julia Maria D'Andrea; CARVALHO, Heraclito Barbosa de; MONTAL, Jose Heverardo da Costa; ADURA, Flavio Emir; YONAMINE, Mauricio
- Use of alcohol and illicit drugs by trauma patients in Sao Paulo, Brazil(2022) BOMBANA, Henrique Silva; BOGSTRAND, Stig Tore; GJERDE, Hallvard; JAMT, Ragnhild Elen Gjulem; CARVALHO, Heraclito Barbosa de; ANDREUCCETTI, Gabriel; BERNINI, Celso de Oliveira; MUNOZ, Daniel Romero; LEYTON, Vilma; GREVE, Julia Maria D'AndreaIntroduction: Alcohol and illicit drugs impair cognitive and psychomotor skills and may thereby increase the risk of involvement in a road traffic crash and other types of injuries. However, the knowledge on the use of psychoactive substances among injured patients presenting to emergency departments in low and middle-income countries remains limited. Aims: To estimate the prevalence of alcohol and illicit drug use among patients with traumatic injuries admitted to an emergency department in Sao Paulo, Brazil. Methods: Blood samples from injured patients requiring hospitalization for more than 24 h due to road traffic crashes, falls, or violence, were collected from July 2018 to June 2019. The samples were analyzed for alcohol and illicit drugs. Results: A total of 376 patients were included in this study; the median age was 36 years and 80% of patients were male. The majority (56%) of injuries resulted from road traffic crashes, with approximately half of them being motorcyclists. Alcohol, drugs, or both were detected in 32% of samples. The proportion that tested positive was highest for males (35%), for the age group 18-39 years (41%), for singles (43%), and for patients injured at nighttime (4 4%). Patients injured due to violence had the highest prevalence of alcohol or drugs in their blood samples (4 4%). Alcohol was most prevalent (23%), followed by cocaine (12%) and cannabis (5%). Conclusion: The use of alcohol and illicit drugs was common among injured patients in Sao Paulo; it was likely a contributing factor in a third of the injurious accidents. Alcohol was the most prevalent substance followed by cocaine and cannabis.
- PREVALENCE OF BEHAVIORAL RISK FACTORS FOR ROAD TRAFFIC INJURIES IN THE CITY OF SAO PAULO: FINDINGS FROM THE BLOOMBERG INITIATIVE FOR GLOBAL ROAD SAFETY (BIGRS) 2015-2017(2018) ANDREUCCETTI, Gabriel; LEYTON, Vilma; CARVALHO, Heraclito B.; SINAGAWA, Daniele M.; BOMBANA, Henrique S.; PONCE, Julio C.; ALLEN, Katharine A.; VECINO-ORTIZ, Andres I.; HYDER, Adnan A.