LUIZ CARLOS CUCE
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Dermatologia, Faculdade de Medicina - Docente
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Study of 1550nm Erbium Glass Laser Fractional non-ablative treatment of photoaging: comparative clinical effects, histopathology, electron microscopy and immunohistochemistry(2023) SICA, Regia Celli Patriota de; RODRIGUES, Consuelo J.; MARIA, Durvanei Augusto; CUCE, Luis CarlosWe, the Editors and Publisher of the Journal of Cosmetic and Laser Therapy have retracted the following article:Regia Celli Patriota de Sica, Consuelo J. Rodrigues, Durvanei Augusto Maria & Luis Carlos Cuce (2016) Study of 1550nm Erbium Glass Laser Fractional non-ablative treatment of photoaging: Comparative clinical effects, histopathology, electron microscopy and immunohistochemistry, Journal of Cosmetic and Laser Therapy, DOI: 10.1080/14764172.2016.1191647Since publication of the accepted author version, authors have not responded to requests to submit corrections and approve proofs, preventing the final publication of the Version of Record (VoR). Authors have also not provided completed copyright forms.We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as 'Retracted'.
- Immunohistochemical Evaluation of Skin Before and After Micro-Ablative Fractional Erbium-Doped Yttrium Aluminum Garnet Laser Treatment(2011) ODO, Lilian M.; ODO, Marina E. Y.; GUEDES, Fernanda; SOTTO, Mirian N.; CUCE, Luiz Carlos
article 18 Citação(ões) na Scopus Intense pulsed light in photoaging: a clinical, histopathological and immunohistochemical evaluation(2011) PATRIOTA, Regia Celli Ribeiro; RODRIGUES, Consuelo Junqueira; CUCE, Luiz CarlosBACKGROUND: Intense pulsed light has been used in the treatment of photoaging without a full understanding of its mechanism of action. OBJECTIVE: To study the effect of intense pulsed light on photoaging and on the skin immune response by means of a clinical and histopathological study, evaluating Langerhans cells (CD1), expression of intercellular adhesion molecule, of CD4 and CD8 lymphocytes and quantification of collagen and elastic fibers. METHODS: In 2006 a total of 26 patients, aged 40 to 65 years, with phototypes II to III (Fitzpatrick scale), were treated for photoaging using intense pulsed light in five sessions with a monthly interval. All the patients were subjected to histological and immunohistochemical evaluation 6 months after treatment. RESULTS: At the end of the treatment clinical improvement was observed in 76.92% of cases. This improvement was associated to a significant increase of collagen (51.33%) and elastic (44.13%) fibers. Intense pulsed light treatment led to a reduction of CD4 lymphocytes and did not alter the amount of CD8 lymphocytes. It also led to a significant increase of small, nonectatic blood vessels, positive intercellular adhesion molecule. CONCLUSION: Facial treatment with intense pulsed light promoted major clinical improvement that was confirmed by histological examination of the skin. This technique is a good treatment option for skin photoaging because it is non-ablative, safe and effective.- Study of 1550-nm Erbium glass laser fractional non-ablative treatment of photoaging: Comparative clinical effects, histopathology, electron microscopy, and immunohistochemistry(2016) SICA, Regia Celli Patriota de; RODRIGUES, Consuelo J.; MARIA, Durvanei Augusto; CUCE, Luis CarlosBackground: Non-ablative fractional lasers have been effectively used in skin rejuvenation. Objectives: This study evaluates the efficacy of 1550-nm Erbium glass laser for facial rejuvenation through the correlation of clinical evaluation and histopathology, immunohistochemistry, and electron microscopy analysis. Methods: Fifteen subjects (average age: 56.4 years, skin types: I-III) with mild-to-moderate photodamage were submitted to biopsies and 3 facial treatments. Data from the photo assessments and the clinical improvement were analyzed 4 months after the treatments. The biopsy skins were fixed in neutral buffered formalin before being embedded in paraffin, and stained with hematoxylin and eosin. The histomorphometric quantification of collagen and elastic fibers; intercellular adhesion molecule 1 expression by immunohistochemistry; and analysis of cell cycle phases, the electrical potential of the mitochondrial, and interleukin (IL)-1, CD34, transforming growth factor (TGF)-beta, and caspase-3 expression by flow cytometry were analyzed. Results: After 4 months of treatment, collagen fibers had increased by 6.68%, and intercellular adhesion molecule 1 (ICAM-1) had increased by 4.47% in vessel area. Significantly enhanced IL-1 and TGF-beta receptor expressions were identified after treatment. Proliferative responses and non-apoptosis-dependent caspase-3 activity were both observed in the cell after dermal treatment. Conclusion: The histopathology, immunohistochemistry, and electron microscopy showed an improvement compatible to the clinical effectiveness after 4 months.
bookPart Apresentação da 4ª edição(2015) FESTA NETO, Cyro; CUCé, Luiz Carlos; REIS, Vitor Manoel Silva dosbookPart Apresentação(2019) FESTA NETO, Cyro; CUCé, Luiz Carlos; REIS, Vitor Manoel Silva dos