DANIEL FUENTES MOREIRA
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conferenceObject Correlation between novelty-seeking and harm-avoidance with depression and anxiety in Parkinson's disease(2012) FONOFF, F. M. C.; FONOFF, E. T.; QUARANTA, T.; BARBOSA, E. R.; TEIXEIRA, M. J.; FUENTES, D.Background: Lower novelty-seeking (NS) and higher harm-avoidance (HA) are characteristics often found in depressive patients. Depression is a comorbidity often found in PD patients. However, recent studies debate whether depressive-like personality traits in PD patients result from dopaminergic degeneration or are related to depression symptoms present in PD. Methods: 61 advanced PD patients and 42 healthy volunteers (HV) were submitted to personality assessment through Temperament and Character Inventory by Cloninger and to depressive and anxiety symptoms assessment through Hamilton Scales for Anxiety (Ham-A) and Depression (Ham-D). Results: PD group showed NS1 significantly lower 4,96 (SD: 2,05) and higher HA4 4,96 (SD: 1,72) than HV. However, PD group and HV did not differ significantly in Anxiety and Depression scores. Conclusions: The present data suggest that depression is not responsible for depressive-like features in PD. Following this reasoning, we can state that these personality traits can be understood independently and, therefore, as part of the motor treatment of the PD patients, a clinical follow-up of the personality traits is necessary. Further studies should investigate those personality traits in PD patients after DBS.conferenceObject Improvement of obsessive-compulsive symptoms after bilateral subthalamic stimulation in Parkinson's disease(2015) FONOFF, F. M. C.; FONOFF, E. T.; BARBOSA, E. R.; MACHADO, R. B.; CURY, R. G.; SANTOS, M. G. G. dos; TEIXEIRA, M. J.; FUENTES, D.- Correlation Between Impulsivity and Executive Function in Patients With Parkinson Disease Experiencing Depression and Anxiety Symptoms(2015) FONOFF, Fernanda Colucci; FONOFF, Erich Talamoni; BARBOSA, Egberto Reis; QUARANTA, Thais; MACHADO, Rachael Brant; ANDRADE, Daniel Ciampi de; TEIXEIRA, Manoel Jacobsen; FUENTES, DanielBackground:Depression and anxiety are comorbidities often associated with Parkinson disease (PD). Recent studies debate on how affective disorders can influence the cognition of patients with PD. This study sought to investigate how depression and anxiety affect specific executive functions and impulsivity traits in these patients. Methods:Twenty-eight patients with advanced PD and 28 closely matched healthy volunteers (HV) were assessed for depressive and anxiety symptoms, impulsivity, executive function and control attention and behavioral response. Results:Compared to the HV group, the PD group showed significantly higher perseverative responses and slowness to adapt to changes in environmental stimuli and longer reaction time for inter-stimulus interval change. Depression symptoms were significantly correlated to motor impulsivity score and total Barratt Impulsiveness Scale (BIS -11) score. Moreover, there was also significant correlation between anxiety symptoms and attentional impulsivity score and total BIS-11 score. Correlation analysis between impulsivity and control attention indicated a positive correlation in commission and a negative correlation in reaction time and detectability in the PD group. Conclusions:The present results suggest that depression and anxiety were highly correlated to impulsivity but not to executive functions changes in these PD patients.