NAIMA MORTARI E SILVA SANTOS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
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conferenceObject CLINICAL, LABORATORY AND EPIDEMIOLOGICAL PROFILE AND TREATMENT OF SEVERE SCHISTOSOMIASIS MANSONI IN A TEACHING HOSPITAL IN SAO PAULO CITY, BRAZIL(2015) MAGALHAES, Maira Reina; ESPIRITO-SANTO, Maria Cristina Carvalho; MORTARI, Naima; LUNA, Expedito Jose; GRYSCHEK, Ronaldo Cesar- Clinical-epidemiological and laboratory profiles of severe Schistosomiasis mansoni infections at a university hospital(2018) ESPIRITO-SANTO, Maria Cristina Carvalho do; MAGALHAES, Maira Reina; MORTARI, Naima; FRANCA, Francisco Oscar de Siqueira; LUNA, Expedito Jose de Albuquerque; GRYSCHEK, Ronaldo Cesar BorgesOBJECTIVE: Schistosomiasis remains a public health problem. This was a descriptive and retrospective study of 42 patients with a severe form of schistosomiasis who were admitted to the outpatient clinic of the Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, in Sao Paulo, Brazil. METHODS: A data collection questionnaire was designed from the patient charts, and the following variables were evaluated: age, sex, place of birth, occupation, signs and symptoms of schistosomiasis, data from laboratory and imaging examinations, data regarding treatment outcomes, and the existence of comorbidities. Statistical analysis was carried out using Statistical Package for the Social Sciences 15.0 and Microsoft Excel 2003 software. The significance levels of the tests were fixed, accepting 5% type 1 error (alpha=0.05). Since this was a retrospective observational study, not all data were available for analysis. RESULTS: The mean age of the patients was 48.24 years; 57.1% were male. Statistically significant associations were observed between splenomegaly and thrombocytopenia (p=0.004) and between splenomegaly and leukopenia (p=0.046); however, only 4.5% of the patients had esophageal hemorrhage. Some patients received a specific treatment; of those, 42% took praziquantel, and 35.4% took oxamniquine. Nonspecific drug therapy was given as follows: 65% received propranolol, 90% omeprazole, and 43.6% aluminum hydroxide. The other treatments were as follows: 92.9% of patients underwent endoscopic treatment, 85% received sclerotherapy, and 62.5% used elastic bandages. CONCLUSION: This preliminary study presents a multidisciplinary outpatient follow-up associated with endoscopic and drug treatments that may be effective at preventing bleeding.