NAIMA MORTARI E SILVA SANTOS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
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conferenceObject CLINICAL, LABORATORY AND EPIDEMIOLOGICAL PROFILE AND TREATMENT OF SEVERE SCHISTOSOMIASIS MANSONI IN A TEACHING HOSPITAL IN SAO PAULO CITY, BRAZIL(2015) MAGALHAES, Maira Reina; ESPIRITO-SANTO, Maria Cristina Carvalho; MORTARI, Naima; LUNA, Expedito Jose; GRYSCHEK, Ronaldo Cesar- The Impact of Restricting Over-the-Counter Sales of Antimicrobial Drugs Preliminary Analysis of National Data(2015) MOURA, Maria Luisa; BOSZCZOWSKI, Icaro; MORTARI, Naima; BARROZO, Ligia Vizeu; CHIARAVALLOTI NETO, Francisco; LOBO, Renata Desordi; LIMA, Antonio Carlos Pedroso de; LEVIN, Anna S.To describe the nationwide impact of a restrictive law on over-the-counter sales of antimicrobial drugs, implemented in Brazil in November 2010.Approximately 75% of the population receives healthcare from the public health system and receives free-of-charge medication if prescribed. Total sales in private pharmacies as compared with other channels of sales of oral antibiotics were evaluated in this observational study before and after the law (2008-2012). Defined daily dose per 1000 inhabitants per day (DDD/TID) was used as standard unit.In private pharmacies the effect of the restrictive law was statistically significant (P<0.001) with an estimated decrease in DDD/TID of 1.87 (s.e.= 0.18). In addition, the trend of DDD/TID before the restrictive law was greater than after the intervention (P<0.001). Before November 2010, the slope for the trend line was estimated as 0.08 (s.e.=0.01) whereas after the law, the estimated slope was 0.03 (s.e.=0.01). As for the nonprivate channels, no difference in sales was observed (P=0.643). The impact in the South and Southeast (more developed) regions was higher than in the North, Northeast, and Mid-West. The state capitals had a 19% decrease, compared with 0.8% increase in the rest of the states.Before the law, the sales of antimicrobial drugs were steadily increasing. From November 2010, with the restrictive law, there was an abrupt drop in sales followed by an increase albeit at a significantly lower rate. The impact was higher in regions with better socio-economic status.