EDUARDO TURIANI HOURNEAUX DE MOURA

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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico

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Autor e Coautores FMUSP-HC Normalizados: GALILEU FERREIRA AYALA FARIAS ×

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  • conferenceObject
    PREDICTORS OF GASTROESOPHAGEAL REFLUX AFTER POEM FOR ACHALASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2019) MOTA, Raquel Cristina L.; MOURA, Eduardo G. de; MOURA, Diogo T. de; MOURA, Eduardo T.; FARIAS, Galileu F.; BRUNALDI, Vitor O.; BERNARDO, Wanderlei M.; SAKAI, Paulo; THOMPSON, Christopher C.
  • article
    Peroral endoscopic myotomy (POEM): a comparative study between Chagasic and idiopathic achalasia
    (2020) FARIAS, Galileu F. A.; MOURA, Diogo T. H. de; MOURA, Eduardo T. H. de; REZENDE, Daniel T. de; HATHORN, Kelly E.; NASI, Ary; QUEIROZ, Natalia S. F.; MOURA, Eduardo G. H. de
    Background and study aims Achalasia can be classified as either primary (idiopathic) achalasia or secondary achalasia, which is a consequence of another systemic disease. Peroral endoscopic myotomy (POEM) is an effective and safe treatment for achalasia. We evaluated the efficacy and safety of POEM in patients with Chagasic achalasia compared to idiopathic achalasia. Patients and methods We evaluated POEM procedures performed at a single institution from November 2016 to January 2018. Demographic data, Eckardt score, lower esophageal sphincter (LES) pressure, body mass index, post-operative erosive esophagitis, adverse events, length of hospital stay, and procedure-related parameters were analyzed. Results Fifty-one patients underwent POEM as a treatment for achalasia in this period (20 patients with Chagasic and 31 with Idiopathic etiology). The overall clinical success rate was 92.1 %, with no statistical difference between groups (90 % in the Chagasic group vs. 93.5 % in the Idiopathic group, P = 0.640). Both groups had significant reduction in Eckardt score and in LES pressure, and increase in bodey mass index (BMI) at 1-year follow-up. There was no statistical difference between groups regarding Eckardt score ( P = 0.439), LES pressure (p = 0.507), BMI ( P = 0.254), post erosive esophagitis (35 % vs. 38.7 %, P = 0.789), adverse events (30 % vs. 12 %, P = 0.163,) length of hospital stay (3.75 days vs. 3.58 days, P = 0.622), and operative time (101.3 min vs. 99.1 min, P = 0.840). Conclusion POEM is an effective and safe treatment for patients with achalasia. There is no difference in POEM outcomes for those patients with Chagasic or Idiopathic achalasia.
  • article 3 Citação(ões) na Scopus
    Peroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication for esophageal achalasia: A single-center randomized controlled trial
    (2022) MOURA, Eduardo Turiani Hourneaux de; JUKEMURA, Jose; RIBEIRO, Igor Braga; FARIAS, Galileu Ferreira Ayala; DELGADO, Aureo Augusto de Almeida; COUTINHO, Lara Meireles Azeredo; MOURA, Diogo Turiani Hourneaux de; SALLUM, Rubens Antonio Aissar; NASI, Ary; SANCHEZ-LUNA, Sergio A.; SAKAI, Paulo; MOURA, Eduardo Guimaraes Hourneaux de
    BACKGROUND Achalasia is a rare benign esophageal motor disorder characterized by incomplete relaxation of the lower esophageal sphincter (LES). The treatment of achalasia is not curative, but rather is aimed at reducing LES pressure. In patients who have failed noninvasive therapy, surgery should be considered. Myotomy with partial fundoplication has been considered the first-line treatment for non-advanced achalasia. Recently, peroral endoscopic myotomy (POEM), a technique that employs the principles of submucosal endoscopy to perform the equivalent of a surgical myotomy, has emerged as a promising minimally invasive technique for the management of this condition. AIM To compare POEM and laparoscopic myotomy and partial fundoplication (LM-PF) regarding their efficacy and outcomes for the treatment of achalasia. METHODS Forty treatment-naive adult patients who had been diagnosed with achalasia based on clinical and manometric criteria (dysphagia score >= II and Eckardt score > 3) were randomized to undergo either LM-PF or POEM. The outcome measures were anesthesia time, procedure time, symptom improvement, reflux esophagitis (as determined with the Gastroesophageal Reflux Disease Questionnaire), barium column height at 1 and 5 min (on a barium esophagogram), pressure at the LES, the occurrence of adverse events (AEs), length of stay (LOS), and quality of life (QoL). RESULTS There were no statistically significant differences between the LM-PF and POEM groups regarding symptom improvement at 1, 6, and 12 mo of follow-up (P = 0.192, P = 0.242, and P = 0.242, respectively). However, the rates of reflux esophagitis at 1, 6, and 12 mo of follow-up were significantly higher in the POEM group (P = 0.014, P < 0.001, and P = 0.002, respectively). There were also no statistical differences regarding the manometry values, the occurrence of AEs, or LOS. Anesthesia time and procedure time were significantly shorter in the POEM group than in the LM-PF group (185.00 +/- 56.89 and 95.70 +/- 30.47 min vs 296.75 +/- 56.13 and 218.75 +/- 50.88 min, respectively; P = 0.001 for both). In the POEM group, there were improvements in all domains of the QoL questionnaire, whereas there were improvements in only three domains in the LM-PF group. CONCLUSION POEM and LM-PF appear to be equally effective in controlling the symptoms of achalasia, shortening LOS, and minimizing AEs. Nevertheless, POEM has the advantage of improving all domains of QoL, and shortening anesthesia and procedure times but with a significantly higher rate of gastroesophageal reflux
  • conferenceObject
    SURGICAL VS. ENDOSCOPIC TREATMENT FOR PANCREATIC PSEUDOCYSTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
    (2018) FARIAS, Galileu F.; VISCONTI, Thiago A.; GONCALVES, Caio V. Tranquillini; GUEDES, Hugo G.; MARTINS, Rafael K.; MOURA, Eduardo T.; MATUGUMA, Sergio E.; SANTOS, Marcos E. dos; SOUZA, Thiago F.; MOURA, Eduardo G. de
  • conferenceObject
    HOW DOES PER ORAL ENDOSCOPIC MYOTOMY COMPARE TO HELLER MYOTOMY IN CHAGAS PATIENTS: THE LATIN AMERICAN SHIFT
    (2018) KAHALEH, Michel; TYBERG, Amy; SURESH, Supriya; LAMBROZA, Arnon; GAIDHANE, Monica; ZAMARRIPA, Felipe; MARTINEZ, Ma Guadalupe; CARAMES, Juan C.; MOURA, Eduardo T.; FARIAS, Galileu F.; MONDRAGON, Oscar V. Hernandez; PORFILIO, Maria G.; NIETO, Jose; REY, Mario; CASASRODRIGUEZ, Fernando; CASTILLO, Bismarck; LUKASHOK, Hannah P.; ROBLES-MEDRANDA, Carlos; MOURA, Eduardo G. de
  • conferenceObject
    THE LEARNING CURVE OF PERORAL ENDOSCOPIC MYOTOMY IN LATIN AMERICA: A SLIDE TO THE RIGHT ?
    (2018) KAHALEH, Michel; TYBERG, Amy; SURESH, Supriya; LAMBROZA, Arnon; CASASRODRIGUEZ, Fernando; REY, Mario; NIETO, Jose; MARTINEZ, Ma Guadalupe; ZAMARRIPA, Felipe; ARANTES, Vitor N.; PORFILIO, Maria G.; GAIDHANE, Monica; FAMILIARI, Pietro; CARAMES, Juan C.; CASTILLO, Bismarck; MOURA, Eduardo T.; FARIAS, Galileu F.; LUKASHOK, Hannah P.; ROBLES-MEDRANDA, Carlos; MOURA, Eduardo G. de
  • conferenceObject
    PERORAL ENDOSCOPIC MYOTOMY (POEM): A COMPARATIVE STUDY BETWEEN CHAGASIC AND IDIOPATHIC ACHALASIA
    (2019) FARIAS, Galileu F.; MOURA, Eduardo T.; MOURA, Diogo T. de; BRUNALDI, Vitor O.; REZENDE, Daniel T.; GALETTI, Facundo; QUEIROZ, Natalia S.; NASI, Ary; SALLUM, Rubens A.; SAKAI, Paulo; MOURA, Eduardo G. de
  • conferenceObject
    PERORAL ENDOSCOPIC MYOTOMY VERSUS SURGICAL MYOTOMY FOR THE TREATMENT OF ACHALASIA: SYSTEMATIC REVIEW AND META-ANALYSIS
    (2018) MARTINS, Rafael K.; BERNARDO, Wanderlei M.; MOURA, Eduardo T.; COUTINHO, Lara M.; FARIAS, Galileu F.; MADRUGA NETO, Antonio C.; DELGADO, Aureo; RIBEIRO, Igor B.; SAKAI, Paulo; SALLUM, Rubens A.; MOURA, Eduardo G. de
  • conferenceObject
    A RANDOMIZED CONTROLLED TRIAL COMPARING PERORAL ENDOSCOPIC MYOTOMY (POEM) VERSUS LAPAROSCOPIC HELLER MYOTOMY WITH FUNDOPLICATION IN THE TREATMENT OF ACHALASIA
    (2019) MOURA, Eduardo T.; FARIAS, Galileu F.; COUTINHO, Lara M.; DELGADO, Aureo; MOURA, Diogo T. de; NASI, Ary; QUEIROZ, Natalia S.; JAYANTHI, Shri K.; SALLUM, Rubens A.; CECCONELLO, Ivan; SAKAI, Paulo; MOURA, Eduardo G. de
  • conferenceObject
    METALLIC STENT VS. MULTIPLE PLASTIC STENTS FOR THE ANASTOMOTIC BILIARY STRICTURE AFTER LIVER TRANSPLANTATION. SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
    (2018) VISCONTI, Thiago A.; BERNARDO, Wanderlei M.; MOURA, Diogo T. de; MOURA, Eduardo T.; GONCALVES, Caio V. Tranquillini; FARIAS, Galileu F.; GUEDES, Hugo G.; FRANZINI, Tomazo; LUZ, Gustavo O.; SANTOS, Marcos E. dos; MOURA, Eduardo G. de