RUBENS GISBERT CURY
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/62 - Laboratório de Fisiopatologia Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/62 - Laboratório de Fisiopatologia Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
16 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 16
- Bilateral striatal lesion due to herpesvirus-6 infection(2015) CURY, Rubens Gisbert; LOPEZ, Willian Omar Contreras
conferenceObject Subthalamic deep brain stimulation modulates small fiber-dependent sensory threshold in Parkinson's disease(2015) CURY, R. G.; GALHARDONI, R.; FONOFF, E. T.; GHILARDI, M. G. dos Santos; MYCZKOWSKI, M.; MARCOLIN, M. A.; BARBOSA, E. R.; TEIXEIRA, M. J.; ANDRADE, D. Ciampi de- SLEEP DISORDER, CHOREA, AND DEMENTIA ASSOCIATED WITH IgLON5 ANTIBODIES(2015) SIMABUKURO, Mateus M.; SABATER, Lidia; ADONI, Tarso; CURY, Rubens Gisbert; HADDAD, Monica Santoro; MOREIRA, Camila Hohi; OLIVEIRA, Imam; BOAVENTURA, Mateus; ALVES, Rosana Cardoso; SOSTER, Leticia Azevedo; NITRINI, Ricardo; GAIG, Carles; SANTAMARIA, Joan; DALMAU, Josep; GRAUS, Francesc
- Trigeminal nerve thickening in chronic inflammatory demyelinating polyneuropathy(2015) GUEDES, Bruno Fukelmann; CURY, Rubens Gisbert
bookPart Roteiro básico de exame neurológico(2015) CURY, Rubens Gisbert- Subthalamic Nucleus Deep Brain Stimulation in Parkinson Disease COMMENT & RESPONSE(2015) CURY, Rubens Gisbert; BARBOSA, Egberto Reis; ANDRADE, Daniel Ciampi de
conferenceObject Effects of STN versus GPi deep brain stimulation on impulse control disorders(2015) GHILARDI, M. G. dos Santos; COUTINHO, A. M. N.; CURY, R. G.; BARBOSA, E. R.; TEIXEIRA, M. J.; ETCHEBEHERE, E.; FONOFF, E. T.- LONG-TERM IMPROVEMENT OF TREMOR AND ATAXIA AFTER BILATERAL DBS OF VOP/ZONA INCERTA IN FXTAS(2015) GHILARDI, Maria Gabriela dos Santos; CURY, Rubens Gisbert; ANGELOS, Jairo Silva dos; BARBOSA, Danilo Costa; BARBOSA, Egberto Reis; TEIXEIRA, Manoel Jacobsen; FONOFF, Erich TalamoniFragile X-associated tremor/ataxia syndrome (FXTAS) is an X-linked adult-onset neurodegenerative disorder that affects carriers of the fragile X mental retardation 1 (FMR1) gene premutation, which is a 55-200 CGG repeat expansion in the 5' untranslated region of the gene.(1) The core symptoms of FXTAS are progressive intention tremor and cerebellar ataxia. These symptoms can be disabling and, when combined, severely reduce the patient's quality of life. Symptomatic control with medication has limited effects.(1) Very few cases have been treated with deep brain stimulation (DBS), mostly in the ventrointermediate thalamic (VIM) nucleus. This treatment results in tremor improvement with either no benefit or worsening of the ataxia and balance.(2-4) We present a patient who experienced long-term tremor control and ataxia improvement after chronic bilateral stimulation of the ventro-oralis posterior thalamic nucleus and zona incerta (VoP/ZI), which resulted in significant improvement in daily life activities.
- Pain in Parkinson's Disease: Current Concepts and a New Diagnostic Algorithm(2015) MYLIUS, Veit; ANDRADE, Daniel Ciampi de; CURY, Rubens Gisbert; TEEPKER, Michael; EHRT, Uwe; EGGERT, Karla Maria; BEER, Serafin; KESSELRING, Juerg; STAMELOU, Maria; OERTEL, Wolfgang H.; MOELLER, Jens Carsten; LEFAUCHEUR, Jean-PascalBackground: Pain is a significant burden for patients with Parkinson's disease (PD) with a high impact on quality of life. The present article aims at summarizing epidemiological, pathophysiological, clinical, and neurophysiological data regarding pain in PD. Methods: In this domain, a procedure of systematic assessment is still lacking for the syndromic diagnosis and should take into account pain characteristics, effects of dopaminergic treatment, motor fluctuations, and non-PD-associated pain. Findings: We propose an original questionnaire addressing an algorithm suitable for daily clinical practice. The questionnaire is based on a three-step approach addressing first the relationship between pain and PD (including temporal relationship with the course of the disease, association with motor fluctuations, and impact of antiparkinsonian treatment), before classifying pain into one of three main syndromes (i.e., musculoskeletal pain, psychomotor restlessness pain, and neuropathic pain). Conclusions: The proposed questionnaire allows the characteristics of each pain type to be determined according to its relationship with the disease and its treatment. The validation of the clinical use of this questionnaire will be the goal of a forthcoming work.
conferenceObject Improvement of obsessive-compulsive symptoms after bilateral subthalamic stimulation in Parkinson's disease(2015) FONOFF, F. M. C.; FONOFF, E. T.; BARBOSA, E. R.; MACHADO, R. B.; CURY, R. G.; SANTOS, M. G. G. dos; TEIXEIRA, M. J.; FUENTES, D.