MARCELO HATANAKA

(Fonte: Lattes)
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina

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  • conferenceObject
    Effect of panretinal photocoagulation on confocal laser scanning ophthalmoscopy and stereo photographic parameters of the optic disc topography in diabetic retinopathy patients
    (2018) AZEVEDO, Breno; ARAUJO, Rafael Barbosa de; CIONGOLI, Marina; CUNHA, Leonardo Provetti; PRETI, Rony Carlos; HATANAKA, Marcelo; ZACHARIAS, Leandro C.; MONTEIRO, Mario L. R.
  • article 0 Citação(ões) na Scopus
  • article 2 Citação(ões) na Scopus
    Comparison of the hypotensor effect between latanoprost versus selective laser trabeculoplasty obtained with the water drinking test
    (2021) GERMANO, Renato Antunes Schiave; HATANAKA, Marcelo; GARCIA, Arthur Sonego; GERMANO, Flavio Augusto Schiave; GERMANO, Caroline Schiave; CID, Felipe Biscegli; GERMANO, Jorge Estefano
    Purpose: Glaucoma is the main cause of irreversible blindness worldwide. Peak intraocular pressure is one of the main risk factors for glaucoma progression, and intraocular pressure reduction remains the only therapeutic strategy for all types of glaucoma. The main purpose of our study was to compare the baseline and peak intraocular pressure reduction obtained with the water drinking test between the two eyes of the same patients using 0.005% latanoprost in one eye and selective laser trabeculoplasty application in the contralateral eye. Methods: This was a prospective, interventional, longitudinal, and randomized clinical trial, in which 30 consecutive glaucomatous patients, medically controlled using latanoprost monotherapy, were recruited from a single ophthalmological center. The patients' eyes were randomized, and one eye was selected for SLT treatment and topical 0.005% latanoprost was introduced in the contralateral eye. The baseline intraocular pressure and peak intraocular pressure were evaluated 1 month (water drinking test 2) and 6 months (water drinking test 3) after treatment. Results: There was no significant difference between the mean pre-washout intraocular pressure in the randomized eyes for selective laser trabeculoplasty and latanoprost (13.6 +/- 2.1 and 13.3 +/- 1.8 mmHg, respectively; p=0.182). Regarding baseline intraocular pressure, there was no significant difference in the water drinking test 2 (p=0.689) and water drinking test 3 (p=0.06) between the groups. There was no significant difference in the intraocular pressure peak between the SLT and latanoprost groups at water drinking test 2 (p=0.771) or water drinking test 3 (p=0.774). Conclusions: The intraocular pressure reduction efficacy is similar between latanoprost and selective laser trabeculoplasty. Glaucomatous patients who are medically controlled with latanoprost and switch treatment to selective laser trabeculoplasty maintain control of intraocular pressure.
  • bookPart
    Glaucoma e cirurgia refrativa
    (2022) MACEDO, Marcelo; HATANAKA, Marcelo
  • article 22 Citação(ões) na Scopus
    Reproducibility of the water drinking test in treated glaucomatous patients
    (2015) BABIC, Mirko; MORAES, C. Gustavo De; HATANAKA, Marcelo; JU, Guilherme; SUSANNA JR., Remo
    BackgroundTo evaluate the reproducibility of intraocular pressure peaks and fluctuation elicited during the water drinking test in treated glaucomatous patients with a long follow-up interval. DesignRetrospective cohort study in a tertiary care practice. ParticipantsThirty-four treated primary open-angle glaucoma patients. MethodsAll patients underwent the water drinking test performed in two consecutive visits without any change in the therapeutic regimen. The mean interval between tests was 4.85 (range: 3-6) months. Reproducibility of peak and fluctuation during the water drinking test was assessed using intraclass correlation coefficients. Bland-Altman analysis was used to assess the agreement of intraocular pressure peaks and fluctuation measured between two consecutive tests. Main Outcome MeasuresIntraclass correlation and agreement of intraocular pressure peaks and fluctuation between visits. ResultsThere were no significant differences in baseline intraocular pressure values (meanstandard deviation, 11.73 +/- 2.36 and 11.61 +/- 2.71mmHg; P=0.72) and peaks (14.55 +/- 3.41 and 15.02 +/- 3.66mmHg, respectively; P=0.163) detected during the water drinking test between the first and second visits. There was also no significant difference between the average intraocular pressure fluctuation values (2.82 +/- 1.99 and 3.41 +/- 2.54mmHg, respectively; P=0.135). Intraocular pressure peaks and fluctuation presented intraclass correlation coefficients of 0.85 (P<0.001) and 0.50 (P<0.001), respectively. ConclusionsOur results demonstrate excellent reproducibility of intraocular pressure peaks during the water drinking test. Intraocular pressure fluctuation did not reveal good reproducibility, though. These results emphasize the applicability of this test to assess treatment efficacy in daily practice and interventional studies.
  • conferenceObject
    Comparison of IOP peak pressure using two different volumes of fluid intake in patients with medically controlled primary open angle glaucoma
    (2018) SUSANNA, Carolina; MORAES, C. Gustavo De; SUSANNA, Bianca Nicolela Nicolela; SUSANNA, Remo; HATANAKA, Marcelo; SUSANNA, Fernanda
  • article 2 Citação(ões) na Scopus
    Clinical relevance of protruded retinal layers in minimum rim width measurement of the optic nerve head
    (2019) TORRES, Lucas A.; JARRAR, Faisal; SHARPE, Glen P.; HUTCHISON, Donna M.; FERRACIOLI-ODA, Eduardo; HATANAKA, Marcelo; NICOLELA, Marcelo T.; VIANNA, Jayme R.; CHAUHAN, Balwantray C.
    Background/aims Optical coherence tomography (OCT) imaging of the optic nerve head minimum rim width (MRW) has recently been shown to sometimes contain components besides extended retinal nerve fibre layer (RNFL). This study was conducted to determine whether excluding these components, termed protruded retinal layers (PRLs), from MRW increases diagnostic accuracy for detecting glaucoma. Methods In this cross-sectional study, we included 123 patients with glaucoma and 123 normal age-similar controls with OCT imaging of the optic nerve head (24 radial scans) and RNFL (circle scan). When present, PRLs were manually segmented, and adjusted MRW measurements were computed. We compared diagnostic accuracy of adjusted versus unadjusted MRW measurement. We also determined whether adjusted MRW correlates better with RNFL thickness compared with unadjusted MRW. Results The median (IQR) visual field mean deviation of patients and controls was -4.4 (-10.3 to -2.1) dB and 0.0 (-0.6 to 0.8) dB, respectively. In the 5904 individual B-scans, PRLs were identified less frequently in patients (448, 7.6%) compared with controls (728, 12.3%; p<0.01) and were present most frequently in the temporal sector of both groups. Areas under the receiver operating characteristic curves and sensitivity values at 95% specificity indicated that PRL adjustment did not improve diagnostic accuracy of MRW, globally or temporally. Furthermore, adjusting MRW for PRL did not improve its correlation with RNFL thickness in either group. Conclusion While layers besides the RNFL are sometimes included in OCT measurements of MRW, subtracting these layers does not impact clinical utility.
  • article 19 Citação(ões) na Scopus
    Predictive Value of the Water Drinking Test and the Risk of Glaucomatous Visual Field Progression
    (2017) MORAES, Carlos G. De; SUSANNA JR., Remo; SAKATA, Lisandro M.; HATANAKA, Marcelo
    Purpose: The purpose of this is to test the hypothesis the intraocular pressure (IOP) peaks during a stress test [the water drinking test (WDT)] can estimate the risk of future visual field progression in treated primary open- angle glaucoma (POAG) patients. Patients and Methods: Design: Prospective, longitudinal study. Setting: Clinical practice. Study population: Treated POAG patients whose IOP was <= 18mmHg and who had no IOPlowering interventions between the date of the WDT and the last eligible visual field. Intervention: At baseline examination, patients underwent the WDT and were then followed at regular intervals with office-based IOP measurements and visual field testing. Main outcome measure: Cox-proportional hazards survival analysis testing the predictive value of IOP peaks during the WDT versus IOP measurements during office hours on visual field progression. Results: A total of 144 eyes of 96 patients with baseline visual field damage ranging from mild to severe followed for a mean of 28 months were analyzed. In the multivariable analysis adjusting for potential confounders, higher IOP peaks during the WDT were predictive of future visual field progression (hazard ratio=1.11; 95% confidence interval, 1.02 to 1.21; P= 0.013). The average and peak IOP during office hours over the same follow-up period were not significantly associated with progression (P= 0.651 and 0.569, respectively). Conclusions: IOP peaks detected with the WDT were predictive of future visual field progression in a treated POAG population. This stress test could be a useful tool for risk assessment in daily practice.
  • conferenceObject
    Water-drinking test for monocular trial with prostaglandin analogue in patients with primary open angle glaucoma or ocular hypertension
    (2014) MARTINS, Wendel; HATANAKA, Marcelo; ALENCAR, Luciana M.; LELIS, Wilma; SUZUKI, Ricardo; LANDIN, Isabella; MORAES, Maiara; SUSANNA, Remo
  • article 29 Citação(ões) na Scopus
    Applications of the water drinking test in glaucoma management
    (2017) SUSANNA JR., Remo; CLEMENT, Colin; GOLDBERG, Ivan; HATANAKA, Marcelo
    Intraocular pressure (IOP) peaks and means have been considered important factors for glaucoma onset and progression. However, peak IOP detection depends only on appropriated IOP checks at office visits, whereas the mean IOP requires longitudinal IOP data collection and may be affected by the interval between visits. Also, IOP peak assessment is necessary to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control. The water-drinking test has gained significant attention in recent years as an important tool to evaluate IOP peaks and instability. The main objective of this review was to present new findings and to discuss the applicability of the water-drinking test in glaucoma management.