MARCELO HATANAKA

(Fonte: Lattes)
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina

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Revista / Livro: Clinical and Experimental Ophthalmology ×

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  • article 22 Citação(ões) na Scopus
    Reproducibility of the water drinking test in treated glaucomatous patients
    (2015) BABIC, Mirko; MORAES, C. Gustavo De; HATANAKA, Marcelo; JU, Guilherme; SUSANNA JR., Remo
    BackgroundTo evaluate the reproducibility of intraocular pressure peaks and fluctuation elicited during the water drinking test in treated glaucomatous patients with a long follow-up interval. DesignRetrospective cohort study in a tertiary care practice. ParticipantsThirty-four treated primary open-angle glaucoma patients. MethodsAll patients underwent the water drinking test performed in two consecutive visits without any change in the therapeutic regimen. The mean interval between tests was 4.85 (range: 3-6) months. Reproducibility of peak and fluctuation during the water drinking test was assessed using intraclass correlation coefficients. Bland-Altman analysis was used to assess the agreement of intraocular pressure peaks and fluctuation measured between two consecutive tests. Main Outcome MeasuresIntraclass correlation and agreement of intraocular pressure peaks and fluctuation between visits. ResultsThere were no significant differences in baseline intraocular pressure values (meanstandard deviation, 11.73 +/- 2.36 and 11.61 +/- 2.71mmHg; P=0.72) and peaks (14.55 +/- 3.41 and 15.02 +/- 3.66mmHg, respectively; P=0.163) detected during the water drinking test between the first and second visits. There was also no significant difference between the average intraocular pressure fluctuation values (2.82 +/- 1.99 and 3.41 +/- 2.54mmHg, respectively; P=0.135). Intraocular pressure peaks and fluctuation presented intraclass correlation coefficients of 0.85 (P<0.001) and 0.50 (P<0.001), respectively. ConclusionsOur results demonstrate excellent reproducibility of intraocular pressure peaks during the water drinking test. Intraocular pressure fluctuation did not reveal good reproducibility, though. These results emphasize the applicability of this test to assess treatment efficacy in daily practice and interventional studies.
  • article 30 Citação(ões) na Scopus
    Applications of the water drinking test in glaucoma management
    (2017) SUSANNA JR., Remo; CLEMENT, Colin; GOLDBERG, Ivan; HATANAKA, Marcelo
    Intraocular pressure (IOP) peaks and means have been considered important factors for glaucoma onset and progression. However, peak IOP detection depends only on appropriated IOP checks at office visits, whereas the mean IOP requires longitudinal IOP data collection and may be affected by the interval between visits. Also, IOP peak assessment is necessary to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control. The water-drinking test has gained significant attention in recent years as an important tool to evaluate IOP peaks and instability. The main objective of this review was to present new findings and to discuss the applicability of the water-drinking test in glaucoma management.
  • article 26 Citação(ões) na Scopus
    Reproducibility of intraocular pressure peak and fluctuation of the water-drinking test
    (2013) HATANAKA, Marcelo; ALENCAR, Luciana M.; MORAES, Carlos G. De; SUSANNA JR., Remo
    Background The water-drinking test has been used as a stress test to evaluate the drainage system of the eye. However, in order to be clinically applicable,a test must provide reproducible results with consistent measurements. This study was performed to verify the reproducibility of intraocular pressure peaks and fluctuation detected during the water-drinking test in patients with ocular hypertension and open-angle glaucoma. Design A prospective analysis of patients in a tertiary care unit for glaucoma treatment. Participants Twenty-four ocular hypertension and 64 open-angle glaucoma patients not under treatment. Methods The water-drinking test was performed in 2 consecutive days by the same examiners in patients not under treatment. Reproducibility was assessed using the intraclass correlation coefficient. Main Outcome Measures Peak and fluctuation of intraocular pressure obtained with the water-drinking test were analysed for reproducibility. Results Eighty-eight eyes from 24 ocular hypertension and 64 open-angle glaucoma patients not under treatment were evaluated. Test and retest intraocular pressure peak values were 28.38 +/- 4.64 and 28.38 +/- 4.56mmHg, respectively (P=1.00). Test and retest intraocular pressure fluctuation values were 5.75 +/- 3.9 and 4.99 +/- 2.7mmHg, respectively (P=0.06). Based on intraclass coefficient, reproducibility was excellent for peak intraocular pressure (intraclass correlation coefficient=0.79) and fair for intraocular pressure fluctuation (intraclass correlation coefficient=0.37). Conclusion Intraocular pressure peaks detected during the water-drinking test presented excellent reproducibility, whereas the reproducibility of fluctuation was considered fair.