JOSE CARLOS SADALLA
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina
25 resultados
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conferenceObject RETROSPECTIVE ANALYSIS OF RADICAL HYSTERECTOMY IN A SINGLE BRAZILIAN CANCER CENTER(2016) CARVALHO, J. P. Mancusi de; GENTA, M. L. Nogueira Dias; SADALLA, J. C.; NOBREGA, F. de Souza; ORTOLAN, N. Macerox; CARVALHO, J. PaulaconferenceObject In Bag Morcellation: details and logistics of the technique(2016) FERNANDES, R.; ARAUJO, M.; SILVA, A. Silva e; CARVALHO, P. Mancusi de; ANTON, C.; GENTA, M. L. Nogueira Dias; RIBEIRO JR., A. Dias; SAMPAIO, D.; MIGLINO, G.; SADALLA, J. C.; CARVALHO, J. PaulaconferenceObject VAGINAL-ASSISTED LAPAROSCOPIC RADICAL HYSTERECTOMY (VALRH): INITIAL EXPERIENCE OF A GYNECOLOGICAL CANCER CENTER IN BRAZIL(2013) FAVERO, G.; SILVA, A. Silva e; ANTON, C.; RIBEIRO, A.; ARAUJO, M. Pereira; SADALLA, J.; MIGLINO, G.; BARACAT, E.; CARVALHO, J.- BORDERLINE OVARIAN TUMORS-10 YEARS SINGLE CENTER EXPERIENCE(2019) FERNANDES, R.; ANTON, C.; SILVA, A. Silva e; CARVALHO, J. P. Mancusi; ARAUJO, M.; GENTA, M. L. Dias; SAMPAIO, D.; MIGLINO, G.; DIAS JR., A.; SADALLA, J. C.; CARVALHO, J. Paula
- Cervical cancer: what's new?(2015) SADALLA, Jose Carlos; ANDRADE, Jurandyr Moreira de; GENTA, Maria Luiza Nogueira Dias; BARACAT, Edmund ChadaCervical cancer is the most common gynecological cancer in Brazil. Among women, it is the second most frequent, second only to breast cancer. It is the fourth leading cause of cancer death in the country, with estimated 15,590 new cases (2014) and 5,430 deaths (2013). In order to update information to improve outcomes, reduce morbidity and optimize the treatment of this cancer, this article will address the advancement of knowledge on cervical cancer. The topics covered include the role of surgery in different stages, treatment of locally advanced carcinomas, fertility preservation, the role of the sentinel lymph node technique, indications and techniques of radiotherapy and chemotherapy, and some special situations.
conferenceObject LYMPHOVASCULAR SPACE INVASION IS HIGHLY ASSOCIATED WITH LYMPH NODE METASTASIS IN ENDOMETRIAL CANCER(2013) CARVALHO, F. M.; ANTON, C.; SADALLA, J. C.; AGUIAR, F. N.; CARVALHO, J. P.conferenceObject Human papillomavirus 16 is an independent predictor of better survival among patients with early cervical cancer(2016) GENTA, M. L. N. D.; LEVI, J. E.; MARTINS, T. R.; SADALLA, J. C.; LOPEZ, R. V. M.; CARVALHO, J. P. M.; CARVALHO, J. P.- Claudin and p53 expression in vulvar lichen sclerosus and squamous-cell carcinoma(2011) SADALLA, Jose Carlos; LOURENCO, Silvia Vanessa; SOTTO, Mirian Nacagami; BARACAT, Edmund Chada; CARVALHO, Jesus PaulaAims Vulvar squamous-cell carcinoma (SCC) is a rare gynaecological cancer. Vulvar SCC has been shown to develop from vulvar intraepithelial neoplasias, which are related to lichen sclerosus (LS). Most studies to date have compared vulvar SCC with LS only morphologically, but no detailed molecular analysis has been performed. The objective was to compare claudin and p53 expression in these diseases and determine if there was any association with expression and vulvar SCC progression. Methods Immunohistochemical analysis was performed in order to determine expression of p53 and claudin 1, 2, 3, 4, 5, 7 and 11 in human vulvar tissue samples from LS, SCC and control patients. Results Claudin 1, 2, 3, 4 and 5 were expressed comparably in the three groups. Claudin 7 and 11 expression was significantly decreased in LS and SCC samples compared with the control group. Expression of p53 was significantly increased in SCC and LS patient samples compared with the control group. Conclusions Claudin 7 and 11 were not expressed in LS and SCC. However, there was no significant difference in expression of any of the claudins between the LS and SCC samples. Furthermore, p53 expression is the highest in SCC patients and lowest in the control group. However, expression of p53 did not vary between samples from isolated LS and LS associated SCC patients, suggesting that increased p53 expression is not the determining factor in the progression of LS lesions to SCC.
conferenceObject NEW APPROACH TO DEFINE PATIENTS WITH LOW RISK LYMPH NODE METASTASIS WITH ENDOMETRIAL CANCER(2015) ANTON, C.; FAVERO, G. M.; SILVA, A. S.; MANCUSI, J. P.; ARAUJO, M. P.; SUAREZ, G. M.; GENTA, M. L. D.; PIATO, D. S. A. M.; DIAS JR., A. R.; FERNANDES, R. P.; SADALLA, J. C.; CARVALHO, J. P.bookPart Tratamento hormonal em mulheres com carcinoma de endométrio(2013) VERA, Miguel Bartolomé; SADALLA, José Carlos
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