ADRIANA FUMIE TATENO

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LIM/52 - Laboratório de Virologia, Hospital das Clínicas, Faculdade de Medicina

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  • article 6 Citação(ões) na Scopus
    Characterization of hepatitis C virus in chronic hepatitis patients: genotypes in the State of Amazonas, Brazil
    (2011) ARAUJO, Ana Ruth; ALMEIDA, Carlos Maurico de; FRAPORTI, Liziara; GARCIA, Nadja; LIMA, Tatiane Amabili de; MAIA, Laura Patricia Viana; TORRES, Katia Luz; TARRAGO, Andrea Monteiro; VICTORIA, Flamir; VICTORIA, Marilu; TATENO, Adriana; LEVI, Jose Eduardo; TALHARI, Sinesio; MALHEIRO, Adriana
    Introduction: In the State of Amazonas, data regarding the prevalence of different genotypes of hepatitis C virus remains scarce. Methods: The genotype of 69 HCV positive patients was determined. An in-house standardized nested-PCR was used to detect HCV RNA. Genotype assignment was based on type-specific motifs on the sequenced amplicons delimited by primers HC11/HC18 from the 5' untranslated region. Results: Of the 69 patients studied, 65.2% were male and 34.8% were female. Genotype 1 showed the greatest prevalence, followed by 3 and 2. Conclusions: These data suggesting that Manaus is the point of arrival of HCV in the State of Amazonas.