PAULO ROBERTO DOS SANTOS SILVA
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
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- Positive effects of football on fitness, lipid profile, and insulin resistance in Brazilian patients with type 2 diabetes(2014) SOUSA, M. V. de; FUKUI, R.; KRUSTRUP, P.; PEREIRA, R. M. R.; SILVA, P. R. S.; RODRIGUES, A. C.; ANDRADE, J. L. de; HERNANDEZ, A. J.; SILVA, M. E. R. daWe evaluated the effects of recreational football training combined with calorie-restricted diet (football+diet) vs calorie-restricted diet alone (diet) on aerobic fitness, lipid profile, and insulin resistance indicators in type 2 diabetes (T2D) patients. Forty-four T2D patients aged 48-68 years (27 females, 17 males) were randomly allocated to the football+diet group (FDG; n=22) or to the diet group (DG; n=22), of whom 19 FDG and 15 DG subjects completed the study. The football training was performed for 3x40min/week for 12 weeks. Dual-energy X-ray absorptiometry scanning, treadmill testing, and fasting blood samplings were performed pre and post-intervention. After 12 weeks, maximal oxygen uptake (VO2max) was elevated (P<0.05) by 10 +/- 4% in FDG but not in DG (-3 +/- 4%, P<0.05). After 12 weeks, reductions in blood triglycerides (0.4 +/- 0.1mmol/L), total cholesterol (0.6 +/- 0.2mmol/L), low-density lipoprotein, and very low-density lipoprotein levels were observed only in FDG. Fat mass decreased (P<0.05) by 3.4 +/- 0.4kg in FDG and 3.7 +/- 0.4kg in DG. The lower (P<0.05) glucagon and homeostatic model assessment of insulin resistance indicated an improvement in insulin sensitivity in FDG. In conclusion, football combined with restricted diet was effective in enhancing VO2max, reducing total cholesterol and triglycerides, and increasing insulin sensitivity, potentially providing better tools for the prevention of T2D complications than diet alone.
- Magnesium status and the physical performance of volleyball players: effects of magnesium supplementation(2014) SETARO, Luciana; SANTOS-SILVA, Paulo Roberto; NAKANO, Eduardo Yoshio; SALES, Cristiane Hermes; NUNES, Newton; GREVE, Julia Maria; COLLI, CeliaThe aim of this study was to test the hypothesis that magnesium supplementation influences the physical performance of volleyball players, as the efficacy of this approach remains questionable. Twenty-five professional male volleyball players were assigned randomly to experimental (350mg Mg center dot d(-1), 4 weeks) and control groups (500mg maltodextrin center dot d(-1), 4 weeks) maintaining inter-group homogeneity of urinary magnesium. Erythrocyte, plasma and urinary magnesium levels, plasma creatine kinase activity, lactate production, maximal oxygen uptake (VO2 max) and plyometric (squat jump, countermovement jump, countermovement jump with arm swing) and isokinetic (peak torque, potency and total work) performances were evaluated before (T-0) and after (T-1) supplementation. Levels of erythrocyte and urinary magnesium and creatine kinase activity and VO2 max remained within normal ranges in both groups. Plasma magnesium decreased significantly only within the experimental group. Significant decreases in lactate production and significant increases (of up to 3cm) in countermovement jump and countermovement jump with arm swing values were detected in the experimental group following magnesium supplementation, but not in the control group at T-1. It is concluded that magnesium supplementation improved alactic anaerobic metabolism, even though the players were not magnesium-deficient.
article 0 Citação(ões) na Scopus Performance during cardiopulmonary exercise test and quality of life of long-distance elderly runners and of non-exerciser elderly(2014) CARDOSO, A.; GREVE, J. M. D.; SANTOS-SILVA, P. R.; ARRABAL, F. F. Leon; SANTOS, U. De PaulaAim. Regular physical exercises are associated to decreased morbidity and mortality, but their relationship with quality of life perception is still not well established. The aim of this paper was to compare cardiopulmonary exercise indicators of functional performance and quality of life (QOL) between a group of untrained elderly (GUE) and a group of trained elderly (GTE) in long-distance running. Methods. GUE was made up of 19 individuals with mean age of 73.5 +/- 6.4 years and GTE by 27 trained elderly with mean age of 73.1 +/- 4.3 years. All were submitted to cardiopulmonary and metabolic evaluation by expired gases analysis. Maximum physical capacity was determined on a motor-driven treadmill with continuous graded protocol and fixed slope of 1%. Quality of Life was evaluated in four domains (physical, psychological, social relations and environment) by Whoqol-Bref questionnaire (WHO) and quantified by total score for each domain. Results. At maximal oxygen intake, GUE and GTE presented: VO2max: 27.0 +/- 5.4 vs. 38.1 +/- 4.5 mL/[kg.min] (P<0.001); O-2 pulse: 11.7 +/- 3.0 vs. 15.5 +/- 2.4 mL/bpm (P<0.001); running speed: 9.7 +/- 2.5 vs. 13.8 +/- 1.7 km/h (P<0.001) and tolerance time: 9.6 +/- 2.9 vs. 14.8 +/- 4.4 mm (P<0.001). QOL measured by Whoqol-Bref questionnaire in four domains for GUE and GTE was respectively: physical: 75.6 +/- 13.6 vs. 80.6 +/- 14.2 (P=0.210), psychological: 79.2 +/- 11.3 vs. 79.2 +/- 13.8 (P=0.893), social relations: 74.6 +/- 14.3 vs. 74.7 +/- 19.1 (P=0.726), environment: 61.4 +/- 15.9 vs. 69.0 +/- 15.5 (P=0.131). Conclusion. GTE cardiopulmonary performance was better as compared to GUE, and QOL of the elderly from both groups was not associated to cardiopulmonary exercise test performance.