WILSON CINTRA JUNIOR
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/04 - Laboratório de Microcirurgia, Hospital das Clínicas, Faculdade de Medicina
LIM/04 - Laboratório de Microcirurgia, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
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- C-Reactive Protein Decrease After Postbariatric Abdominoplasty(2012) CINTRA, Wilson; MODOLIN, Miguel; FAINTUCH, Joel; GEMPERLI, Rolf; FERREIRA, Marcus C.In a prospective study, indices of glucose homeostasis, lipid profile, and systemic inflammation were monitored after an aesthetic abdominoplasty, aiming to scrutinize the possible metabolic benefits for abdominal fat removal. Premenopausal females with substantial weight loss (N = 40) undergoing circumferential abdominoplasty (index group, n = 20) or augmentation mammoplasty with mastopexy (controls, n = 20) were recruited. All of them originally underwent Roux-en-Y gastric bypass. Variables included BMI, white blood cell count, C-reactive protein, hemoglobin, total cholesterol and fractions, triglycerides, glucose, and HbA1c. Follow-up reached 20.3 +/- 13.6 months for index cases and 29.5 +/- 17.4 months for controls. The metabolic and inflammatory indices improved after the bariatric surgery. Subsequent monitoring indicated a stable body weight and biochemical profile in both groups. The exceptions were HDL cholesterol and C-reactive protein, which respectively increased and diminished after the abdominoplasty, consistent with an inflammatory and metabolic advantage for this operation. This is the first long-term study in a weight-stable population to point out such a pattern after abdominoplasty.
- Systemic Inflammatory Reaction After Silicone Breast Implant(2011) SILVA, Maira M.; MODOLIN, Miguel; FAINTUCH, Joel; YAMAGUCHI, Camila M.; ZANDONA, Cintia B.; CINTRA JR., Wilson; FUJIWARA, Haroldo; CURI, Rui; GEMPERLI, Rolf; FERREIRA, Marcos C.Systemic inflammation after augmentation mammaplasty with modern silicone implants is not currently recognized. In a prospective controlled study, C-reactive protein and other variables were monitored, aiming to test this hypothesis in a young cohort of patients. Females (18-30 years old, BMI = 18.5-30 kg/m(2), N = 52) were consecutively recruited for breast implant (n = 24, Group I) and for abdominal liposuction (n = 28, Group II/Controls). Patients were interviewed at baseline and followed until 6 months after operation. Variables included demographic and clinical information, surgical outcome, inflammatory markers and autoantibodies. Operations were well tolerated, without surgical or infectious complications. Mean prosthesis size was 258 +/- A 21 ml (range = 220-280) and mean aspirate of liposuction was 1972 +/- A 499 ml (range = 1200-3000). Preoperative, 2-month, and 6-month C-reactive protein concentrations for breast implant patients were 1.3 +/- A 1.2, 4.8 +/- A 3.0, and 4.3 +/- A 6.4 mg/l and for liposuction 3.5 +/- A 2.7, 3.5 +/- A 2.1, and 2.2 +/- A 2.2 mg/l, respectively. Change at 2 months was significant (p = 0.001). Autoantibody investigation failed to reveal remarkable aberrations, except for anticardiolipin elevation, which was nearly symmetrical in the two groups. C-reactive protein levels increased after operation and correlated with proinflammatory and procoagulatory indices. A mild increase in anticardiolipin IgM occurred but differences between populations were lacking. Despite excellent cosmetic outcomes and lack of complications, acute phase reaction could signal ongoing immunogenicity of silicone and long-term monitoring is recommended.
- Aesthetic rehabilitation after bariatric surgery(2013) CINTRA, W. Jr.; FAINTUCH, J.Sustained and lifelong weight loss for severely obese people is not anymore an impossible dream, and a Swedish article suggests, half jokingly, that this is the new fairy tale of the ugly duckling (Olbers, Lakartidningen 108:2570-2573, 2011). The example is appropriate because for health care professionals, resolution of obesity means reversal of diabetes, hyperlipidemia, and other cardiovascular risk factors. For the majority of the patients all these results are secondary. Priority is getting beautiful and achieving a rich and fulfilling emotional life. That is the reason why plastic interventions are the most frequent new operations after bariatric treatment, and as many as 85 % of this population desire subsequent body contouring maneuvers (Gusenoff et al., Plast Reconstr Surg 122:951-958, 2008; Highton et al. J Plast Reconstr Aesthet Surg 65:426-432, 2012). Fortunately this specialty has responded to the challenge, and both old and new techniques are being successfully adapted to the specificities of the patients who shed much weight and suffer from lax and redundant skinfolds and widespread lipodystrophy. Principal procedures such as abdominoplasty, mammaplasty, thigh lift, brachioplasty and others are described, emphasizing the experience of the Hospital das Clinicas Service during more than 15 years. © 2013 Springer-Verlag Berlin Heidelberg. All rights are reserved.