NATALIA VIU DEGASPARE
Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
9 resultados
Resultados de Busca
Agora exibindo 1 - 9 de 9
- What Will Be the Consensus of Pediatric Intensivists Regarding the Diagnosis of Pediatric Acute Respiratory Distress Syndrome?(2015) MUNOZ, Gabriela Ortega Cisternas; DEGASPARE, Natalia Viu; DELGADO, Artur Figueiredo; CARVALHO, Werther Brunow de
conferenceObject Ventilatory Practices And Adjunctive Therapies In Children With Ards: A Prospective Observational Study(2014) BARREIRA, E. R.; SHIEH, H. H.; SUZUKI, A. S.; DEGASPARE, N. V.; CAVALHEIRO, P. O.; MUNOZ, G. O. C.; MARTINES, J. A. D. S.; LANE, C.; CARVALHO, W. B.; GILIO, A. E.; PRECIOSO, A. R.- Comment regarding pediatric severe acute respiratory syndrome coronavirus 2: clinical presentation, infectivity, and immune responses(2021) FERRANTI, Juliana Ferreira; DEGASPARE, Natalia Viu; MAU, Luciana Becker; DELGADO, Artur Figueiredo; CARVALHO, Werther Brunow de
- Epidemiology and Outcomes of Acute Respiratory Distress Syndrome in Children According to the Berlin Definition: A Multicenter Prospective Study(2015) BARREIRA, Eliane R.; MUNOZ, Gabriela O. C.; CAVALHEIRO, Priscilla O.; SUZUKI, Adriana S.; DEGASPARE, Natalia V.; SHIEH, Huei H.; MARTINES, Joao A. D. S.; FERREIRA, Juliana C.; LANE, Christianne; CARVALHO, Werther B.; GILIO, Alfredo E.; PRECIOSO, Alexander R.Objectives: In 2012, a new acute respiratory distress syndrome definition was proposed for adult patients. It was later validated for infants and toddlers. Our objective was to evaluate the prevalence, outcomes, and risk factors associated with acute respiratory distress syndrome in children up to 15 years according to the Berlin definition. Design: A prospective, multicenter observational study from March to September 2013. Setting: Seventy-seven PICU beds in eight centers: two private hospitals and six public academic hospitals in Brazil. Patients: All children aged 1 month to 15 years admitted to the participating PICUs in the study period. Interventions: None. Measurements and Main Results: All children admitted to the PICUs were daily evaluated for the presence of acute respiratory distress syndrome according to the American-European - Consensus Conference and Berlin definitions. Of the 562 patients included, acute respiratory distress syndrome developed in 57 patients (10%) and 58 patients (10.3%) according to the Berlin definition and the American-European Consensus Conference definition, respectively. Among patients with acute respiratory distress syndrome according to the Berlin definition, nine patients (16%) were mild, 21 (37%) were moderate, and 27 (47%) were severe. Compared with patients without acute respiratory distress syndrome, patients with acute respiratory distress syndrome had significantly higher severity scores, longer PICU and hospital length of stay, longer duration of mechanical ventilation, and higher mortality (p < 0.001). The presence of two or more comorbidities and admission for medical reasons were associated with development of acute respiratory distress syndrome. Comparisons across the three the Berlin categories showed significant differences in the number of ventilator-free days (21, 20, and 5 d, p = 0.001) and mortality for severe acute respiratory distress syndrome (41%) in comparison with mild (0) and moderate (15%) acute respiratory distress syndrome(p = 0.02). No differences in PICU or hospital stay were observed across the groups. Conclusions: The Berlin definition can identify a subgroup of patients with distinctly worse outcomes, as shown by the increased mortality and reduced number of ventilator-free days in pediatric patients with severe acute respiratory distress syndrome.
article 1 Citação(ões) na Scopus When Is the Appropriate Time for Pediatric Acute Respiratory Distress Syndrome Classification?(2015) DEGASPARE, Natalia Viu; MUNOZ, Gabriela Ortega Cisternas; DELGADO, Artur Figueiredo; CARVALHO, Werther Brunow de- SARS-CoV-2 in cardiac tissue of a child with COVID-19-related multisystem inflammatory syndrome(2020) DOLHNIKOFF, Marisa; FERRANTI, Juliana Ferreira; MONTEIRO, Renata Aparecida de Almeida; DUARTE-NETO, Amaro Nunes; GOMES-GOUVEA, Michele Soares; DEGASPARE, Natalia Viu; DELGADO, Artur Figueiredo; FIORITA, Carolina Montanari; LEAL, Gabriela Nunes; RODRIGUES, Regina Maria; CHAIM, Khallil Taverna; PINHO, Joao Renato Rebello; CARNEIRO-SAMPAIO, Magda; MAUAD, Thais; SILVA, Luiz Fernando Ferraz da; CARVALHO, Werther Brunow de; SALDIVA, Paulo Hilario Nascimento; CALDINI, Elia Garcia
conferenceObject Epidemiology And Outcomes Of Ards In Critically Ill Children According To The Berlin Definition: A Prospective Study(2014) BARREIRA, E. R.; SHIEH, H. H.; SUZUKI, A. S.; MUNOZ, G. O. C.; DEGASPARE, N. V.; CAVALHEIRO, P. O.; MARTINES, J. A. D. S.; LANE, C.; GILIO, A. E.; CARVALHO, W. B.; PRECIOSO, A. R.- Peripherally inserted central catheters are associated with lower risk of bloodstream infection compared with central venous catheters in paediatric intensive care patients: a propensity-adjusted analysis(2017) YAMAGUCHI, Ricardo Silveira; NORITOMI, Danilo Teixeira; DEGASPARE, Natalia Viu; MUNOZ, Gabriela Ortega Cisternas; PORTO, Ana Paula Matos; COSTA, Silvia Figueiredo; RANZANI, Otavio T.Purpose: Central line-associated bloodstream infection (CLABSI) is an important cause of complications in paediatric intensive care units (PICUs). Peripherally inserted central catheters (PICCs) could be an alternative to central venous catheters (CVCs) and the effect of PICCs compared with CVCs on CLABSI prevention is unknown in PICUs. Therefore, we aimed to evaluate whether PICCs were associated with a protective effect for CLABSI when compared to CVCs in critically ill children. Methods: We have carried out a retrospective multicentre study in four PICUs in Sao Paulo, Brazil. We included patients aged 0-14 years, who needed a CVC or PICC during a PICU stay from January 2013 to December 2015. Our primary endpoint was CLABSI up to 30 days after catheter placement. We defined CLABSI based on the Center for Disease Control and Prevention's National Healthcare Safety Networks (NHSN) 2015 surveillance definitions. To account for potential confounders, we used propensity scores with inverse probability weighting. Results: A total of 1660 devices (922 PICCs and 738 CVCs) in 1255 children were included. The overall CLABSI incidence was 2.28 (95% CI 1.70-3.07)/1000 catheter-days. After covariate adjustment using propensity scores, CVCs were associated with higher risk of CLABSI (adjHR 2.20, 95% CI 1.05-4.61; p = 0.037) compared with PICCs. In a sensitivity analysis, CVCs remained associated with higher risk of CLABSI (adjHR 2.18, 95% CI 1.02-4.64; p = 0.044) after adding place of insertion and use of parenteral nutrition to the model as a time-dependent variable. Conclusions: PICC should be an alternative to CVC in the paediatric intensive care setting for CLABSI prevention.
- Invasive Measurement of Global End-Diastolic Volume: Is It Possible to Add Any Data Besides Clinical Parameters?(2015) DEGASPARE, Natalia Viu; CAINO, Felipe de Oliveira Rezende; DELGADO, Artur Figueiredo; CARVALHO, Werther Brunow de