ANA PAULA SAMY TANAKA KOTINDA
Índice h a partir de 2011
4
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Endoscopic ultrasound evaluation of portal cavernoma cholangiopathy and endoscopic management of choledochal variceal rupture during ERCP(2024) KOTINDA, Ana Paula Samy Tanaka; POUJOL-ROBERT, Armelle; PAYANCE, Audrey; LEENHARDT, Romain; DUBOC, Marine Camus; DRAY, Xavier; CHAPUT, Ulriikka
- Fecal microbiota transplantation improves metabolic syndrome parameters: systematic review with meta-analysis based on randomized clinical trials(2020) PROENCA, Igor M.; ALLEGRETTI, Jessica R.; BERNARDO, Wanderley M.; MOURA, Diogo T. H. de; NETO, Alberto M. Ponte; MATSUBAYASHI, Carolina O.; FLOR, Marcelo M.; KOTINDA, Ana P. S. T.; MOURA, Eduardo G. H. deObesity and metabolic syndrome are important health problems that can lead to significant morbidity/mortality as well as subsequent health concerns. Alterations in the gut microbiota have been implicated in both obesity and metabolic syndrome. Fecal Microbiota Transplantation (FMT) has emerged as a new promising therapeutic approach aimed at manipulating the gut microbiota in various chronic diseases. Randomized clinical trials assessing the use of FMT in obese and metabolic syndrome patients have been reported. The purpose of this systematic review with meta-analysis using randomized clinical trials (RCT) is to evaluate the role of FMT for the treatment of obesity and metabolic syndrome and its impact on clinically relevant parameters. We searched the main databases, as well as the gray literature, to identify RCTs comparing FMT from lean donor (s) vs placebo for obese/metabolic syndrome patients. We included all studies that utilized any form of placebo (sham, saline, autologous FMT, or placebo capsules). Six studies met the inclusion criteria and were included for final analysis with a total of 154 patients. We looked for clinically significant parameters related to obesity and metabolic syndrome and organized the findings into early (2-6 weeks after intervention) and late (12 weeks after intervention) outcomes. Two to 6 weeks after intervention, mean HbA(1c) was lower in the FMT group (MD =-1.69 mmol/L, CI [-2.88,-0.56], P = .003) and mean HDL cholesterol was higher in the FMT group (MD = 0.09 mmol/L, CI [0.02, 0.15], P = .008). There was no difference in obesity parameters 6 to 12 weeks after intervention. No serious adverse events were reported. The findings for this meta-analysis show that FMT may have a role for the treatment of metabolic syndrome, but there is currently not enough evidence to support its use in clinical practice. High-quality well-powered RCTS with longer follow-up are necessary to clarify the role of FMT in this patient cohort. (C) 2020 The Author(s).
- Approach to Endoscopic Procedures: A Routine Protocol from a Quaternary University Referral Center Exclusively for Coronavirus Disease 2019 Patients(2020) FRANZINI, Tomazo Antonio Prince; KOTINDA, Ana Paula Samy Tanaka; MOURA, Diogo Turiani Hourneaux de; BADANA, Marcia Lopes Vicente; MEDEIROS, Marion Sielfeld de; LIMA, Patricia Goulart Rodrigues; MELLO, Brigitte Feiner de; KAYANO, Rafael Priante; CARMONA, Maria Jose Carvalho; ROCHA, Marcelo Cristiano; CAMPOS, Aleia Faustina; MCCARTY, Thomas R.; GUIMARAES, Thais; MOURA, Maria Luisa do Nascimento; THOMPSON, Christopher C.; MOURA, Eduardo Guimaraes Hourneaux deOBJECTIVES: The present coronavirus disease (COVID-19) pandemic has ushered in an unprecedented era of quality control that has necessitated advanced safety precautions and the need to ensure the adequate protection of healthcare professionals (HCPs). Endoscopy units, endoscopists, and other HCP may be at a significant risk for transmission of the virus. Given the immense burden on the healthcare system and surge in the number of patients with COVID-19, well-designed protocols and recommendations are needed. We aimed to systematically characterize our approach to endoscopic procedures in a quaternary university hospital setting and provide summary protocol recommendations. METHOD: This descriptive study details a COVID-19-specific protocol designed to minimize infection risks to patients and healthcare workers in the endoscopy unit. RESULTS: Our institution, located in Sao Paulo, Brazil, includes a 900-bed hospital, with a 200-bed-specific intensive care unit exclusively designed for patients with moderate and severe COVID-19. We highlighted recommendations for infection prevention and control during endoscopic procedures, including appropriate triage and screening, outpatient management and procedural recommendations, role and usage of personal protective equipment (PPE), and role and procedural logistics involving COVID-19-positive patients. We also detailed hospital protocols for reprocessing endoscopes and cleaning rooms and also provided recommendations to minimize severe acute respiratory syndrome coronavirus 2 transmission. CONCLUSION: This COVID-19-specific administrative and clinical protocol can be replicated or adapted in multiple institutions and endoscopy units worldwide. Furthermore, the recommendations and summary protocol may improve patient and HCP safety in these trying times.
- Efficacy of Intragastric Balloons for Weight Loss in Overweight and Obese Adults: a Systematic Review and Meta-analysis of Randomized Controlled Trials(2020) KOTINDA, Ana Paula Samy Tanaka; MOURA, Diogo Turiani Hourneaux de; RIBEIRO, Igor Braga; SINGH, Shailendra; PONTE NETO, Alberto Machado da; PROENCA, Igor Mendonca; FLOR, Marcelo Mochate; SOUZA, Karina Lopes de; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux deIntragastric balloons (IGB) are the most widely used endoscopic bariatric and metabolic therapies. We aimed to evaluate the efficacy of IGB in comparison with sham or lifestyle interventions for weight loss in overweight and obese patients. This systematic review and meta-analysis was performed following the PRISMA guidelines. Electronic searches were performed to identify randomized controlled trials, which compared IGB with sham or lifestyle intervention. Thirteen RCTs with 1523 patients were included. The difference in mean %EWL and %TWL at follow-up was 17.98%, and 4.40%, respectively, which was significantly higher in the IGB group. Similarly, the difference in mean AWL and BMIL was 6.12 kg, and 2.13 kg/m(2), respectively. IGB therapy is more effective than lifestyle intervention alone for weight loss in overweight and obese adults.
conferenceObject ENDOSCOPIC ULTRASOUND-ASSISTED BY ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF GASTROINTESTINAL SUBEPITHELIAL LESIONS: SYSTEMATIC REVIEW AND META-ANALYSIS(2023) GOMES, Romulo; OLIVEIRA, Guilherme Henrique Peixoto de; SASSO, Joao Guilherme Ribeiro Jordao; KOTINDA, Ana Paula; MATSUBAYASHI, Carolina; VERAS, Matheus; BERNARDO, Wanderley; CAVASSOLA, Paulo; MOURA, Eduardo De- Adverse Events and Complications with Intragastric Balloons: a Narrative Review (with Video)(2021) RIBEIRO, Igor Braga; KOTINDA, Ana Paula Samy Tanaka; SANCHEZ-LUNA, Sergio A.; MOURA, Diogo Turiani Hourneaux de; MANCINI, Fabio Catache; SOUZA, Thiago Ferreira de; MATUGUMA, Sergio Eiji; SAKAI, Christiano Makoto; ROCHA, Rodrigo Silva de Paula; LUZ, Gustavo de Oliveira; SANTOS, Marcos Eduardo Lera dos; CHAVES, Dalton Marques; FRANZINI, Tomazo Antonio Prince; MOURA, Eduardo Turiani Hourneaux de; MOURA, Eduardo Guimaraes Hourneaux deIntragastric balloon (IGB) is a minimally invasive and reversible therapy for weight loss with a good efficacy and safety profile. Introduced in the 1980s, IGBs have significantly evolved in the last couple of decades. They mechanically act by decreasing the volume of the stomach and its reservoir capacity, delaying gastric emptying, and increasing satiety leading to a subsequent weight loss. Despite the low rates of complications and mortality associated with IGBs, adverse events and complications still occur and can range from mild to fatal. This review aims to provide an update on the current scientific evidence in regard to complications and adverse effects of the use of the IGB and its treatment. This is the first comprehensive narrative review in the literature dedicated to this subject.
conferenceObject EFFICACY OF INTRAGASTRIC BALLOONS FOR WEIGHT LOSS IN OVERWEIGHT AND OBESE ADULTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS(2020) KOTINDA, Ana Paula S.; BERNARDO, Wanderlei M.; PONTE, Alberto M. da; PROENCA, Igor M.; SINGH, Shailendra; MOURA, Diogo T. de; THOMPSON, Christopher C.; MOURA, Eduardo G. de