GABRIEL WOLF OSELKA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Pediatria, Faculdade de Medicina - Docente
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
bookPart Alta em pediatria - aspectos éticos e jurídicos(2022) HIRSCHHEIMER, Mario Roberto; BARSANTI, Claudio; CONSTANTINO, Clóvis Francisco; OSELKA, Gabriel WolfbookPart Prefácio(2020) OSELKA, GabrielbookPart Relação médico-paciente - as autonomias do médico, da criança e dos responsáveis e o termo de consentimento livre e esclarecido(2022) HIRSCHHEIMER, Mario Roberto; CONSTANTINO, Clóvis Francisco; OSELKA, Gabriel Wolf- Rubella Vaccination of Unknowingly Pregnant Women: The Sao Paulo Experience, 2001(2011) SATO, Helena K.; SANAJOTTA, Andrea Torres; MORAES, Jose Cassio; ANDRADE, Joelma Queiroz; DUARTE, Geraldo; CERVI, Maria Celia; CURTI, Sueli P.; PANNUTI, Claudio Sergio; MILANEZ, Helaine; PESSOTO, Monica; FLANNERY, Brendan; OSELKA, Gabriel W.Background. Rubella vaccination is contraindicated during pregnancy. During mass immunization of women of childbearing age against rubella, women unknowingly pregnant may be vaccinated. To evaluate the effects of rubella vaccination during pregnancy, the Brazilian state of Sao Paulo conducted a follow-up study of pregnant women vaccinated during a rubella campaign in 2001. Methods. Women vaccinated during pregnancy were reported to a national surveillance system. In the state of Sao Paulo, follow-up of vaccinated women included household interviews. Serum samples from vaccinated women were tested for antirubella antibodies to classify susceptibility to rubella infection. Children born to susceptible mothers were tested for evidence of congenital rubella infection and evaluated for signs of congenital rubella syndrome. Results. The Sao Paulo State Health Department received 6473 notifications of women vaccinated during pregnancy. Serology performed for 5580 women identified 811 (15%) that were previously susceptible. Incidence of spontaneous abortion or stillbirth among previously susceptible vaccinated women was similar to women with prior immunity. Twenty-seven (4.7%) of 580 newborns tested had evidence of congenital rubella infection; none had congenital rubella syndrome. Conclusions. Mass rubella vaccination of women of childbearing age was not associated with adverse birth outcomes or congenital rubella syndrome among children born to women vaccinated during pregnancy.
- A critical appraisal of the recommendations for the use of meningococcal conjugate vaccines(2012) SAFADI, Marco Aurelio Palazzi; BEREZIN, Eitan Naaman; OSELKA, Gabriel WolfObjectives: To assess the epidemiology of meningococcal disease (MD) in Brazil and the impact that recent evidence and lessons learned from the introduction of meningococcal C conjugate (MCC) vaccines into immunization programs may have on different strategies of vaccine use. Sources: Non-systematic review of the MEDLINE, SciELO and LILACS databases covering the period from 2000 to 2011. Summary of the findings: Meningococcal disease is endemic in Brazil, with periodic occurrence of outbreaks. Most cases are associated with serogroup C and the highest incidence rates are observed in infants, encouraging the introduction of MCC vaccine in the National Immunization Program in 2010 for children under 2 years old. The introduction of MCC vaccines into immunization programs in Europe, Canada and Australia proved to be effective, with dramatic reduction in the incidence of serogroup C meningococcal disease, not only in the vaccinated, but also in the unvaccinated individuals. Long-term effectiveness of MCC vaccines was dependent on a combination of antibody persistence, immunologic memory and herd protection. Recent evidence indicating that antibody persistence is not long-lasting in young immunized children, and that immunologic memory is not fast enough to protect them against the disease, emphasize the importance of herd protection to maintain the population protected. Conclusions: The rapid decline of antibody titers in children vaccinated in the first years of life suggests the need to incorporate booster doses before adolescence, especially in locations like Brazil, where the immunization program did not incorporate catch-up campaigns including adolescents, lacking the herd immunity effect.
bookPart Imunizações(2015) VALLADA, Marcelo Genofre; OSELKA, Gabriel Wolf