IVAN APRAHAMIAN
Projetos de Pesquisa
Unidades Organizacionais
LIM/66, Hospital das Clínicas, Faculdade de Medicina
4 resultados
Resultados de Busca
Agora exibindo 1 - 4 de 4
- Assessment of impairment in activities of daily living in mild cognitive impairment using an individualized scale(2016) CHAVES, Giseli de Fatima dos Santos; OLIVEIRA, Alexandra Martini; CHAVES, Juliana Aparecida dos Santos; FORLENZA, Orestes Vicente; APRAHAMIAN, Ivan; NUNES, Paula VillelaMild impairment in activities of daily living (ADL) can occur in Mild Cognitive Impairment (MCI), but the nature and extent of these difficulties need to be further explored. The Canadian occupational performance measure (COPM) is one of the few individualized scales designed to identify self-perceived difficulties in ADL. The present study investigated impairments in ADL using the COPM in elderly with MCI. A total of 58 MCI patients were submitted to the COPM for studies of its validity and reliability. The COPM proved a valid and consistent instrument for evaluating ADL in elderly MCI patients. A total of 74.6% of the MCI patients reported difficulties in ADL. Of these problems, 41.2% involved self-care, 31.4% productivity and 27.4% leisure. This data further corroborates recent reports of possible functional impairment in complex ADL in MCI.
- Qualitative analysis of the Clock Drawing Test by educational level and cognitive profile(2014) FABRICIO, Aline Teixeira; APRAHAMIAN, Ivan; YASSUDA, Mônica SanchesThe use of a qualitative scale for the Clock Drawing Test (CDT) may add information about the pattern of errors committed. Objective: To translate and adapt the Modified Qualitative Error Analysis of Rouleau into Brazilian Portuguese and to examine the pattern of errors according to educational level and cognitive profile. Method: 180 adults (47-82 years) completed the CDT. Participants were stratified into age and educational levels and separated between those with and without changes in cognitive screening tests (Mini-Mental State Examination, Verbal Fluency). Results: No significant differences were found in CDT scores among age groups. Among participants without cognitive impairment, those with lower education often presented graphic difficulties, conceptual deficits and spatial deficits. Participants with cognitive deficits, demonstrated more frequently conceptual and spatial errors. Conclusion: The qualitative analysis of the CDT may contribute to the identification of cognitive changes. Education level has to be taken into consideration during the analysis.
- The use of the Clock Drawing Test in bipolar disorder with or without dementia of Alzheimer's type(2014) APRAHAMIAN, Ivan; RADANOVIC, Marcia; NUNES, Paula Villela; LADEIRA, Rodolfo Braga; FORLENZA, Orestes VicenteThere is limited data regarding the cognitive profile from screening tests of older adults with bipolar disorder (BD) with dementia. Objective: To investigate the Clock Drawing Test (CDT) among older adults with BD with and without Alzheimer's disease (AD). Method: 209 older adults (79 with BD without dementia and 70 controls; 60 with AD, being 27 with BD) were included to evaluate the performance of three CDT scoring scales, beyond the Mini-Mental State Examination (MMSE) and verbal fluency (VFT). Results: Patients with BD without dementia presented with lower scores in MMSE, VF and one CDT scoring scale than controls. Patients with BD and AD presented with lower scores in VF and CDT scoring scales than patients with only AD. All CDT scales presented similar sensitivity and specificity for BD and non-BD groups. Conclusion: Elderly subjects with BD showed greater impairment in CDT in both groups of normal cognition and AD.
- Screening for Alzheimer's disease in low-educated or illiterate older adults in Brazil: a systematic review(2019) ORTEGA, Luciane de Fatima Viola; APRAHAMIAN, Ivan; BORGES, Marcus Kiiti; CACAO, Joao de Castilho; YASSUDA, Monica SanchesCognitive screening instruments are influenced by education and/or culture. In Brazil, as illiteracy and low education rates are high, it is necessary to identify the screening tools with the highest diagnostic accuracy for Alzheimer's disease (AD). Objective: To identify the cognitive screening instruments applied in the Brazilian population with greater accuracy, to detect AD in individuals with a low educational level or who are illiterate. Methods: Systematic search in SciELO, PubMed and LILACS databases of studies that used cognitive screening tests to detect AD in older Brazilian adults with low or no education. Results: We found 328 articles and nine met the inclusion criteria. The identified instruments showed adequate or high diagnostic accuracy. Conclusion: For valid cognitive screening it is important to consider sociocultural and educational factors in the interpretation of results. The construction of specific instruments for the low educated or illiterate elderly should better reflect the difficulties of the Brazilian elderly in different regions of the country.