BEATRIZ MANGUEIRA SARAIVA RAMANHOLO
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina
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bookPart 0 Citação(ões) na Scopus Occupational allergy in elite runners(2014) TEIXEIRA, R. N.; ROMANHOLO, B. S.; AGONDI, R. C.; PINTO, A. F.; MARTINS, M. de Arruda; CARVALHO, C. R. F.Background: The prevalence of allergy, asthma and airwayinflammation and hyperresponsiveness in elite athletes has increased overthe years and appears to vary between sport modalities. Although allergicand respiratory diseases have been extensively studied in enduranceathletes, especially swimmers and winter sports athletes, the prevalencein elite runners remains unknown.Objective: The aims of this study were to screen allergy symptoms inelite runners and to evaluate the airway responsiveness and airwayinflammatory cells in these athletes.Methods: One hundred and thirty elite runners were invited tocomplete the Allergy Questionnaire for Athletes (AQUA©), a validatedquestionnaire to screen allergy in athletes, in addition to answeringquestions related to training history, running distance per week and bestrace time in a marathon or half-marathon. A subgroup of 36 nonasthmaticathletes also performed the methacholine challenge test,sputum induction and cardiopulmonary exercise testing. Airwayinflammation was quantified via cellular airway infiltration.Results: The presence of allergy was based on the AQUA© totalscore, and athletes were classified as either AQUA+ or AQUA- (a score=5 or <5, respectively). Sixty-one athletes (60%) reported allergysymptoms, and no significant differences between the groups (AQUA+and AQUA-) were observed regarding gender, age, running experience,weekly training volume or best performance time in a half-marathon ormarathon (p>0.05). Most athletes presented airway inflammation witheosinophilic predominance (23.6%); however, only 8.3% of the eliterunners had a positive response to methacoline challenge.Conclusions: Our study demonstrated that elite runners have a highprevalence of allergy and eosinophilic airway inflammation withoutevidence of airway hyperresponsiveness; this finding was independent ofgender, age, quantity of training and performance. © 2014 Nova Science Publishers, Inc. All rights reserved.