CLAUDIA GIULI SANTI
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
4 resultados
Resultados de Busca
Agora exibindo 1 - 4 de 4
- Exfoliative erythroderma as a clinical manifestation of autoimmune bullous diseases(2016) MIYAMOTO, Denise; BATISTA, Daniel I. S.; SANTI, Claudia G.; MARUTA, Celina W.; DELGADO, Livia; AOKI, Valeria
- Systemic retinoid treatment in a case of hyperkeratotic lichenoid paraneoplastic pemphigus(2022) YENDO, Tatiana Mina; MIYAMOTO, Denise; SANTI, Claudia G.
- Clinical and epidemiological profile of patients attended in a vulvar clinic of the dermatology outpatient unit of a tertiary hospital during a 4-year period(2019) GONCALVES, Daniel Luiz M.; ROMERO, Raissa L.; FERREIRA, Paula L.; SANTI, Claudia G.Background Vulvar complaints are among the most frequent causes for a woman to visit a healthcare provider. The diseases of this area of the body may be a challenge to diagnose. In this study, we assess epidemiologic and clinical data of patients in an outpatient vulvar clinic in the dermatology department of a tertiary hospital. Methods We performed an observational retrospective study of patients who attended our consultation service for vulvar diseases at the Dermatology Division at Hospital das Clinicas da Faculdade de Medicina da USP during a 4-year period. Data were obtained by patient medical records and by phone. Results During the 4-year period under study, a total of 136 patients were treated in the outpatient service specialized in vulvar care. All patients were included in the study. The most frequent diagnoses were lichen sclerosus et atrophicus (64.7%), lichen planus (8.8%), and vitiligo (8%). We registered that 26.7% of the patients showed extravulvar involvement. Conclusions Women with vulvar diseases need specific care, considering not only genital aspects but also all skin changes. In this context, the dermatologist is a very well trained professional to take good and complete care of these patients. However, ideally vulvar clinics should have a multidisciplinary team.
- Stevens-Johnson syndrome and toxic epidermal necrolysis - retrospective review of cases in a high complexity hospital in Brazil(2020) MEDEIROS, Marcella P.; CARVALHO, Caroline H. C.; SANTI, Claudia G.; AVANCINI, JoaoBackground Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare conditions characterized by epidermal necrosis, mostly caused by drugs. Despite the rarity of these conditions, morbidity and mortality are high (even in previously healthy patients), and they may be associated with permanent sequelae. Methods A retrospective study conducted at a quaternary hospital in Brazil in a period of 10 years. Results The sample was composed by 41 patients with SJS, SJS/TEN, and TEN confirmed by skin biopsy. Antibiotics and anticonvulsants were the most frequently implied drug classes, and phenytoin was the most important individual culprit drug. In this study, 12.2% of the patients had sequelae, being ophthalmological lesions the most common and one case of a newly described hearing loss. The mortality rate was 16.7% in patients with TEN. Conclusions This study describes the largest Latin American case series of SJS and TEN with the diagnosis proven by skin biopsy and adds important data regarding the profile of the disease in Brazil. It also describes a novel sequelae of hearing loss.