ANA CRISTINA DE OLIVEIRA SOLIS
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
10 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 10
- Impact of post-traumatic stress disorder on oral health(2017) SOLIS, Ana Cristina de Oliveira; ARAUJO, Alvaro Cabral; CORCHS, Felipe; BERNIK, Marcio; DURAN, Erica Panzani; SILVA, Claudio; LOTUFO-NETO, FranciscoBackground: The stress experienced as an intense and traumatic event can increase the odds of orofacial pain, affect the biomechanics of masticatory system and compromise the periodontal health. This study was conducted to investigate the impact of post-traumatic stress disorder (PTSD) on oral health. Methods: A case-control study with a convenience sample was designed. Probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing, and plaque were recorded at 6 sites per tooth. A visual analog scale (VAS) was used to evaluate the pain after probing. The Research Diagnostic Criteria for Temporomandibular Disorders Axis II (RDC/TMD Axis II) and Structured Clinical Interview (DSM-IV) were also applied. The final sample comprised 38 PTSD patients and 38 controls. Results: Patients with PTSD had a higher degree of chronic pain, more depression and nonspecific physical symptoms (including and excluding pain) compared with the control group (Fisher exact test p < 0.001, and Chi-squared test, p < 0.001,< 0.001,< 0.001, respectively). Patients with PTSD also had more pain after periodontal probing compared with controls (Mann-Whitney, p = 0.037). The prevalence of sites with CAL or PPD = 4, = 5, = 6 were not different between the groups. Age was associated with moderate periodontitis (multivariable logistic regression model, OR = 3.33, 95% CI = 1.03-10.75, p = 0.04). Limitation: The severity of PTSD precluded an ample sample size. Conclusions: Patients with PTSD presented a worse RDC/TMD Axis II profile, more pain after periodontal probing, and no difference related to periodontal clinical parameters. More studies are needed to confirm these findings.
- Predictors of quality of life in Brazilian medical students: a systematic review and meta-analysis(2019) SOLIS, Ana C.; LOTUFO-NETO, FranciscoObjective: To examine predictors associated with quality of life (QoL) in Brazilian medical students. Methods: PubMed, PsycINFO, EMBASE, LILACS, and Google Scholar were searched for research articles in English or Portuguese published through August 2018. Observational studies that measured QoL with standard instruments were selected. Three instruments were used to evaluate QoL: the World Health Organization QoL questionnaires (WHOQOL-Bref and WHOQOL-100) and 36-item Short Form Health Survey (SF-36). Hedges' g was used to calculate effect sizes. A random-effects model was used in meta-analyses. PRISMA guidelines were followed. Results: The initial search retrieved 8,504 articles; 24 met the eligibility criteria for systematic review, and seven for meta-analyses of gender (n=3,402 students). Predictors of QoL such as gender, years of medical school(years of study), economic class, educational environment, academic efficacy, depression, burnout, resilience, empathic concern, sleep difficulties, chronic illness, body mass index, and leisure-time physical activity were identified in the systematic review. The most frequent predictors of QoL detected in Brazilian medical students were associated with gender and years of study. Conclusions: Female medical students had lower QoL scores in the physical health and psychological domains of WHOQOL-Bref compared to male students. Specific interventions should be designed for this group as appropriate.
- Interpersonal psychotherapy for treatment of obesity: A systematic review and meta-analysis(2023) TOLEDO, Priscila R.; LOTUFO-NETO, Francisco; VERDELI, Helen; GOULART, Alessandra C.; MARQUES, Andrea Horvath; SOLIS, Ana Cristina de Oliveira; WANG, Yuan-PangBackground: Social and interpersonal context are associated with the onset and persistence of psychiatric dis-orders. We compared the effects of short-term interpersonal psychotherapy (IPT) on weight loss, binge eating behaviors, and depressive symptoms against cognitive-behavioral therapy (CBT), health education (HE), and behavioral weight loss (BWL).Methods: We searched until May 28th, 2022 following databases: PubMed, CINAHL, Science Direct, Web of Science, EMBASE, and Scopus. Articles on parallel randomized clinical trials were included. Outcomes were body mass index (BMI), binge days (bulimic episode), and depressive symptoms. These outcomes were self-reported or measured with specific scales (BMI) or instrument (depressive symptoms).Results: The initial search retrieved 820 articles, a total of 10 studies met the eligibility criteria, and seven were included in the meta-analysis. Participants with overweight/obesity were women (62-100 %), aged between 11 and 50 years. There was a trivial to small effect on BMI favoring IPT over other interventions (standardized mean difference [SMD] =-0.10; 95%CI:-0.27 to 0.07, I2 = 0 %), especially when compared to health education (SMD =-0.21; 95%CI:-0.54 to 0.12, I2 = 0 %); no effect on number of binge days (SMD =-0.09; 95%CI:-0.30 to 0.11, I2 = 0 %); and a small effect on depressive symptoms (SMD =-0.25, 95%CI =-0.50 to 0.00, I2 = 0 %).Limitations: Small number of studies, the discrepancy in age cohorts, and racial diversity. Psychotherapeutic protocols and assessment tools had to be adapted across studies.Conclusions: Patients with overweight/obesity and depression had some benefit from IPT when compared with other interventions. In view of existing evidence, an IPT program adapted to obesity could help to achieve reliable and long-term effects.
- Suicide among college students: much ado about nothing?(2022) ALTAVINI, Camila Siebert; ASCIUTTI, Antonio Paulo Rinaldi; SOLIS, Ana Cristina Oliveira; SANTANA, Geilson Lima; LOTUFO-NETO, Francisco; WANG, Yuan-Pang
conferenceObject ECT VERSUS SHAM FOR CLOZAPINE RESISTANT SCHIZOPHRENIA: A SECONDARY ANALYSIS OF A PILOT STUDY BASED ON PANSS-30 FACTOR ANALYTIC DIMENSIONS AND THE PANSS-6(2020) MELZER-RIBEIRO, Debora Luciana; SOLIS, Ana Cristina Oliveira; TISSOT, Maria Cistina Grilli; ELKIS, Helio- Evaluation of periodontitis in hospital outpatients with major depressive disorder. A focus on gingival and circulating cytokines(2016) SOLIS, Ana Cristina de Oliveira; MARQUES, Andrea Horvath; DOMINGUEZ, Wagner Vasques; PRADO, Euthymia Brandao de Almeida; PANNUTI, Claudio Mendes; LOTUFO, Roberto Fraga Moreira; LOTUFO-NETO, FranciscoAn imbalance in stimulated cytokine production is associated with the etiopathogenesis of numerous diseases such as major depressive disorder (MDD) and periodontal disease. Increased cytokine levels have been reported in the gingival crevicular fluid (GCF) of patients with MDD. Thirty-six outpatients with MDD participated in this study. Each outpatient was age-matched (+/- 3 years) with a healthy control (n = 36). The patients were controlled for race and smoking habits. Unstimulated and stimulated interleukin 6 (IL-6), interleukin 1 beta (IL-1 beta), and interferon-gamma (INF-gamma) production in whole blood culture (WBC) and IL-6 and IL-1 beta levels in the GCF were evaluated. Circulating levels of IL-6 and IL-1 beta (unstimulated) as well as GCF IL-1 beta were modestly lower in MDD patients, compared to the levels in age-matched controls (Mann-Whitney, p = 0.002, 0.0075, ANCOVA, p = 0.025, respectively). In the unstimulated group, there was no correlation between the levels of circulating IL-6 and GCF IL-6 (r = 0.07, p = 0.67), and between the levels of circulating IL-1 beta and the IL-1 beta level in the CGF (r = -0.08, p = 0.63). In the LPS stimulation group, there was no correlation between the levels of circulating levels of IL-6 and GCF IL-6 (r = 0.02, p= 0.91) or between the circulating IL-1 beta and GCF IL-1 beta (r = 0.13, p= 0.42). We observed modest immunosuppression in MDD patients (evaluated by no stimulation whole blood culture [WBC]), especially in patients with melancholic depression, chronic depression, and severe depression.
- Revisiting evidence of primary prevention of suicide among adult populations: A systematic overview(2022) ALTAVINI, Camila Siebert; ASCIUTTI, Antonio Paulo Rinaldi; SOLIS, Ana Cristina Oliveira; WANG, Yuan-PangBackgrounds: : Primary prevention of suicidal behaviors in the general population is required to interrupt the trend of self-inflicted deaths worldwide. We reviewed the evidence of the efficacy of primary prevention of suicide among the adult population. Methods: : This is an overview of systematic reviews. We searched PubMed, EMBASE, Scopus, PsycINFO, and Cochrane databases to identify articles on suicide prevention strategies in non-clinical populations. For the purpose of overview, only systematic reviews were eligible. Primary outcomes: The outcomes of the present study were changes in the number of suicide death or suicide behaviors. Two reviewers assessed the methodological quality and the risk of bias of included studies. Results: : From the initial 2,315 records, 32 articles met inclusion criteria. Evidence of reduction of suicide-related outcomes was detected, but of small magnitude. Most multicomponent prevention programs were delivered to specific populations, comprising strategies such as restriction to lethal means, educational programs, and gatekeeper training. Means restriction was the single intervention that showed some evidence of individual efficacy in reducing suicide. There is evidence that poor quality of media reporting is related with increasing suicide and better-quality reports could help suicide prevention. Most of the included SRs were of critically-low methodological quality. Limitations: : Publication bias, reporting bias, study designs, outcome definition and article overlap across studies are the main concerns. Conclusions: : Multicomponent programs and means restriction have indicated a reduction of suicide rates, mainly in specific populations. There is insufficient evidence to recommend a widespread implementation of suicide primary prevention in the general population.
- Suicide ideation among Brazilian college students: Relationship with academic factors, mental health, and sexual abuse(2023) ALTAVINI, Camila Siebert; ASCIUTTI, Antonio Paulo Rinaldi; SANTANA, Geilson Lima; SOLIS, Ana Cristina Oliveira; ANDRADE, Laura Helena; OLIVEIRA, Lucio Garcia; ANDRADE, Arthur Guerra; GORENSTEIN, Clarice; WANG, Yuan-PangBackground: Suicide is one of the leading causes of death among youth and its occurrence among college students is a matter of great concern. Challenges of transitional adulting and mental illness increase the likelihood of suicidal cognition in students. The objective of present study was to investigate the prevalence of suicide ideation and associated factors in a representative sample of Brazilian college students (n = 12,245).Methods: Data were drawn from a nationwide survey and further subjected to estimate the prevalence of suicide ideation and its association with socio-demographic and academic characteristics. We performed logistic regression analyses upon a conceptual framework, considering individual and academic factors.Results: The point-prevalence of suicide ideation among college students was 5.9 % (SE = 0.37). In the final regression model, variables associated with the likelihood of suicide ideation were psychopathology, sexual abuse, and academic variables, such as dissatisfaction with the chosen undergraduate course (OR = 1.86; IC95 % 1.43-2.41) and low academic performance (OR = 3.56; IC95 % 1.69-7.48). Having children and religious affiliation were inversely associated with the likelihood of suicide ideation.Limitations: Participants were recruited from state capitals, which limited data generalizability to non-urban college students.Conclusions: The impact of academic life on the mental health of students should be carefully monitored in in-campus pedagogical and health services. Early identification of poor-performance students with social disad-vantages could indicate vulnerable ones who are much in need of psycho-social support.
bookPart Psiquiatria baseada em evidências(2021) SOLIS, Ana Cristina de Oliveira; ELKIS, Helio- Self-reported bruxism in patients with post-traumatic stress disorder(2024) SOLIS, Ana Cristina de Oliveira; CORCHS, Felipe; DURAN, erica Panzani; SILVA, Claudio; REAL, Natalia Del; ARAUJO, alvaro Cabral; WANG, Yuan-Pang; LOTUFO-NETO, FranciscoObjective The present study aimed to investigate the association between self-reported awake/sleep bruxism, and orofacial pain with post-traumatic stress disorder (PTSD). Methods A case-control study with a convenience sample was designed. Participants were recruited from a university-based Trauma Ambulatory. The diagnosis of PTSD was established through a clinical interview and the Structured Clinical Interview (SCID-I/P). Thirty-eight PTSD patients and 38 controls completed the Research Diagnostic Criteria for Temporomandibular Disorders Axis-II to categorize awake/sleep bruxism and orofacial pain. Following this, we performed a short clinical examination of the temporomandibular joint and extraoral muscles. Results Adjusted logistic regression analysis showed that awake bruxism was associated with PTSD (OR = 3.38, 95% CI = 1.01-11.27, p = 0.047). Sleep bruxism was not associated with any covariate included in the model. In a Poisson regression model, PTSD (IRR = 3.01, 95% CI = 1.38-6.55, p = 0.005) and the muscle pain/discomfort (IRR = 5.12, 95% CI = 2.80-9.36, p < 0.001) were significant predictors for current orofacial pain. Conclusions PTSD was associated with self-reported awake bruxism and low-intensity orofacial pain. These conditions were frequent outcomes in patients previously exposed to traumatic events. Clinical relevance We suggest including a two-question screening for bruxism in psychiatry/psychology interviews to improve under-identification and to prevent harmful consequences at the orofacial level.