EDUARDO DE PAULA MIRANDA
Projetos de Pesquisa
Unidades Organizacionais
LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina
21 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 21
conferenceObject yyy CONCORDANCE BETWEEN INTERVIEW-BASED AND SELF-ADMINISTERED SCORES USING THE PORTUGUESE VERSION OF THE SEXUAL HEALTH INVENTORY FOR MEN (SHIM) IN PATIENTS WITH ERECTILE DYSFUNCTION (ED)(2017) REGGIO, E.; MIRANDA, E. P.; JUNQUEIRA, R. G.; TIMM, O.; SETTE, M. J.; BELLUCCI, C. H. S.; GOMES, C. M.; JR, J. BessaconferenceObject ASSESSMENT OF THE MALE SEXUAL QUOTIENT SCALE RELIABILITY TO EVALUATE SEXUAL FUNCTION OF MEN WITH SPINAL CORD INJURY(2015) MIRANDA, Eduardo; GOMES, Cristiano; BESSA JUNIOR, Jose de; CASTRO FILHO, Jose de; BELLUCCI, Carlos; BATTISTELLA, Linamara; BARROS FILHO, Tarcisio; CARVALHO, Fabricio; ABDO, Carmita; BRUSCHINI, Homero; NAHAS, William; SROUGI, Miguel- The role of urinary KIM-1, NGAL, CA19-9 and beta 2-microglobulin in the assessment of ureteropelvic junction obstruction in adults(2017) MIRANDA, Eduardo P.; DUARTE, Ricardo J.; BESSA JR., Jose de; LOPES, Roberto I.; SROUGI, Victor; ANDRADE, Hiury S.; BANDEIRA, Rodolfo A. S. T.; ARAP, Marco A.; MITRE, Anuar I.; VIANA, Nayara I.; REIS, Sabrina T.; LEITE, Katia R. M.; SROUGI, MiguelPurpose: The objective of this study is to evaluate the diagnostic properties of urinary biomarkers in adults with ureteropelvic junction obstruction: KIM-1, NGAL, CA19-9, and beta 2-microglobulin. We also assessed urinary biomarker concentrations following pyeloplasty. Material and methods: We prospectively studied adults from December 2013 to February 2015. We included 47 patients with a mean age of 38.6 +/- 12.7 years. Each patient provided four samples of voided urine for biomarker measurement, one at pre-operative consultation and the others at 1, 3, and 6 months of post-operative follow-up. The control group consisted of 40 healthy individuals with no hydronephrosis on ultrasound evaluation. Results: KIM-1 had an area under the curve of 0.79 (95% CI 0.70-0.89), NGAL 0.71 (95% CI 0.61-0.83), CA19-9 0.70 (95% CI 0.60-0.81), and beta 2-microgloblin 0.61 (95% CI 0.50-0.73). KIM-1 was the most sensitive marker with a cut-off of 170.4 pg/mg creatinine (sensitivity 91.4%, specificity 59.1%), whereas CA19-9 was the most specific with a cut-off of 51.3 U/mg creatinine (sensitivity 48.9%, specificity 88.0%). Urinary concentrations of biomarkers decreased after pyeloplasty. Conclusions: The evaluation of urinary biomarkers is useful in adults undergoing pyeloplasty. KIM-1, NGAL, and CA19-9 were elevated and significantly decreased after surgery.
- Laparoscopic pyeloplasty as an alternative to nephrectomy in adults with poorly functioning kidneys due to ureteropelvic junction obstruction(2021) NASCIMENTO, Bruno; ANDRADE, Hiury S.; MIRANDA, Eduardo P.; BARBOSA, Joao Arthur Brunhara Alves; MOSCARDI, Paulo R.; ARAP, Marco A.; I, Anuar Mitre; SROUGI, Miguel; SROUGI, Victor; DUARTE, Ricardo J.Objectives To evaluate outcomes of laparoscopic pyeloplasty (LP) in adults with poorly functioning kidney due to ureteropelvic junction obstruction (UPJO). Methods A retrospective comparative analysis was performed between adult patients who underwent LP due to UPJO with differential renal function (DRF) <= 15% and DRF > 15%. LP success rate and complications were assessed. LP success was defined as symptoms improvement and DRF improvement or stabilization. DRF and estimated glomerular filtration rate (eGFR) were analyzed before and 12 months after surgery to evaluate renal function recovery. DRF was estimated using Tc-99 m DMSA renal scintigraphy. Results Among 121 LP performed in the study period at our institution, 15 and 42 were included in the DRF <= 15% and DRF > 15% groups, respectively. At a median follow-up of 17.8 months, all patients with DRF <= 15% reported symptoms improvement. LP success rate was 86.7% and 90.5% (p = 0.65) for patients with DRF <= 15% and DRF > 15%, respectively. There were no complications in the DRF <= 15% group, while there were three complications recorded in the DRF > 15% group (Clavien 2 and 3b). In the DRF <= 15% group, mean pre-operative and post-operative DRF was 9.5% +/- 3.6 and 10.5% +/- 7.8 (p = 0.49), respectively. Median pre-operative and post-operative eGFR was 68.5 ml/min and 79.8 ml/min (p = 0.93), respectively. Two patients had DRF improvement after LP. Conclusions LP in adult patients with UPJO and poor function kidneys is an effective and safe procedure. DRF recovery is seen in a minority of the patients; however, LP is an alternative to nephrectomy.
conferenceObject DIAGNOSTIC ACCURACY OF URINARY beta 2-MICROGLOBULIN, CA19-9, NGAL AND KIM-1 IN URETEROPELVIC JUNCTION OBSTRUCTION IN ADULTS(2016) MIRANDA, Eduardo; BESSA JR., Jose de; LOPES, Roberto; SOUGI, Victor; ANDRADE, Hiury; BANDEIRA, Rodolfo; ARAP, Marco; MITTRE, Anuar; VIANA, Nayara; REIS, Sabrina dos; LEITE, Katia; SOUGI, Miguel; DUARTE, RicardoconferenceObject NOMOGRAM USING METABOLIC SYNDROME COMPONENTS TO PREDICT TESTOSTERONE DEFICIENCY SYNDROME IN MEN(2018) NOVAES, Monique; MIRANDA, Eduardo P.; SILVA, Caroline S.; TIRABOSCHI, Ricardo; ALVAIA, Mateus; PASCHOALIN, Victor; BORBA, Lucas; BASTOS-NETTO, Jose Murillo; GOMES, Cristiano; BESSA JR., JoseconferenceObject IMPACT OF CAMERA DEVIATION ON CURVATURE ASSESSMENTS USING GONIOMETER AND 2D PHOTOGRAPHIES(2018) NASCIMENTO, Bruno; CERQUEIRA, Ivan; MIRANDA, Eduardo P.; BESSA JR., Jose; FIDELIS, Renato; GUGLIELMETTI, Giuliano; BATAGELO, Carlos; SILVA, Gabriel C.; NAHAS, William; SROUGI, Miguel; CHIESA, Giorgio; CURY, JoseconferenceObject EVALUATION OF LAPAROSCOPIC PYELOPLASTY AS AN ALTERNATIVE TO NEPHRECTOMY IN ADULTS WITH POORLY FUNCTIONING KIDNEYS DUE TO URETEROPELVIC OBSTRUCTION(2016) NASCIMENTO, Bruno; MIRANDA, Eduardo; SROUGI, Victor; ARAP, Marco; ANDRADE, Hiwy; MITRE, Anuar; BANDEIRA, Rodolfo; SROUGI, Miguel; DUARTE, RicardoconferenceObject IMPACT OF SPINAL CORD INJURY IN MALE SEXUAL FUNCTION(2012) CASTRO, Jose; GOMES, Cristiano; BESSA JR., Jose; BRUSCHINI, Homero; ABDO, Carmita; ABREU, Luiz; ARAUJO FILHO, Julio; SOUZA, Daniel; SCAZUFCA, Marcia; MIRANDA, Eduardo; SROUGI, Victor; BATTISTELLA, Linamara; BARROS, Tarcisio; SROUGI, Miguel- Transvaginal ultrasonography for trigonitis diagnosis in women(2023) RIBEIRO-FILHO, Leopoldo Alves; BRAZ, Natalia Doratioto Serrano Faria; SUARTZ, Caio Vinicius; BALSIMELLI, Amaury Padilha; HIRASAKI, Felipe; MIRANDA, Eduardo; SIQUEIRA, Matheus; MITRE, Anuar Ibrahim; GOMES, Cristiano Mendes; NAHAS, William CarlosObjectiveChronic trigonitis (CT) is usually diagnosed through cystoscopy which is invasive and expensive. Thus, an accurate non-invasive diagnostic method is necessary. The objective of this study is to determine the efficacy of transvaginal bladder ultrasound (TBU) for CT diagnosis. MethodsBetween 2012 and 2021, 114 women (17-76 years old) with recurrent urinary tract infection (RUTI) and history of antibiotic resistance were evaluated with TBU by a single ultrasonographer. As a control group, TBU was performed in 25 age-matched women with no previous history of UTI, urological or gynecological conditions. All patients with RUTI had undergone a cystoscopy with biopsy for diagnostic confirmation at the time of trigone cauterization. ResultsThickening of trigone mucosa (>3 mm) was detected in all patients with RUTI and represented the most relevant criteria for trigonitis diagnosis on TBU. Other TBU findings in CT are: irregular and interrupted mucosa lining (96.4%), free debris in the urine (85.9%), increased blood flow at doppler (81.5%), mucosa shedding and tissue flaps. Biopsy showed CT with erosive pattern (58%) or non-keratinizing metaplasia (42%). Diagnostic agreement index between TBU and cystoscopy was 100%. In the control group, normal trigone mucosa is ultrasonographically regular, continuous, with thickness <= 3 mm and there is no debris in the urine. ConclusionsTBU proved to be an efficient, inexpensive and minimally invasive method to diagnose CT. To our knowledge, this is the first article that reports the use of transvaginal ultrasound as an alternative method for diagnosing trigonitis.
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