LUCIANA ALVARENGA DA SILVA
Projetos de Pesquisa
Unidades Organizacionais
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Facial somatosensorial evaluation in idiopathic trigeminal neuralgia(2012) SILVA, Luciana Alvarenga da; SIQUEIRA, Silvia Regina Dowgan Tesseroli de; SIQUEIRA, Jose Tadeu Tesseroli de; TEIXEIRA, Manoel Jacobsen
- The role of xerostomia in burning mouth syndrome: a case-control study(2014) SILVA, Luciana Alvarenga da; SIQUEIRA, Jose Tadeu Tesseroli de; TEIXEIRA, Manoel Jacobsen; SIQUEIRA, Silvia Regina Dowgan Tesseroli deObjective : To assess the efficacy of anti-xerostomic topical medication (urea 10%) in patients with burning mouth syndrome (BMS). Method : Thirty-eight subjects diagnosed with BMS according to the International Association for the Study of Pain guidelines were randomized to either placebo (5% sodium carboxymethylcellulose, 0.15% methyl paraben, and 10% glycerol in distilled water qsp 100 g) or treatment (urea 10%) to be applied to the oral cavity 3-4 times per day for 3 months. The patients were evaluated before and after treatment with the following instruments: the EDOF-HC protocol (Orofacial Pain Clinic – Hospital das Clínicas), a xerostomia questionnaire, and quantitative sensory testing. Results : There were no differences in salivary flow or gustative, olfactory, or sensory thresholds (P>0.05). Fifteen (60%) patients reported improvement with the treatments (P=0.336). Conclusion : In conclusion, there were no differences between groups, and both exhibited an association between reported improvement and salivation.
- Quantitative sensory testing in fibromyalgia and hemisensory syndrome: comparison with controls(2013) SILVA, Luciana Alvarenga da; KAZYIAMA, Helena Hideko Seguchi; TEIXEIRA, Manoel Jacobsen; SIQUEIRA, Silvia Regina Dowgan Tesseroli deFibromyalgia syndrome (FS) is a chronic painful condition with sensory, motor and affective dysfunctions. Few studies had investigated the trigeminal area, and little is known about its association with hemisensory syndrome, which is characterized by chronic pain restricted to hemibody. Our objective was to investigate sensorial abnormalities with quantitative sensory testing of patients with FS and patients with hemisensory syndrome, compared to controls. Thirteen patients diagnosed with FS according to the American College of Rheumatology, and 12 patients with hemisensory syndrome were evaluated and compared to 25 age-gender-matched controls. They were investigated with a quantitative sensory testing protocol including gustative, olfactory, cold, warm, touch, vibration, electric, deep and superficial pain thresholds and the corneal reflex evaluation. The patients had higher gustative thresholds for salty and bitter. In general, patients with FS had somatosensory thresholds higher than the controls; however, patients with hemisensory syndrome had only superficial pain thresholds increased, in both body sides and not only in the area affected by pain. Patients with hemisensory syndrome can be a subgroup of FS, different from nondermatomal somatosensory deficits which are characterized by chronic pain with hypoesthesia in hemibody. The bilateral hypoalgesia supports that pain pathways play a key role in this condition, with no compromise of other sensorial modalities.
- Quantitative sensory testing in elderly: longitudinal study(2018) SILVA, Luciana Alvarenga da; JALUUL, Omar; TEIXEIRA, Manoel Jacobsen; SIQUEIRA, Jose Tadeu Tesseroli de; JACOB FILHO, Wilson; SIQUEIRA, Silvia Regina Dowgan Tesseroli deObjective: To evaluate elderly patients in a geriatric service, along with their sensory characteristics and their association with clinical aspects. Methods: This was a descriptive longitudinal study. We enrolled 36 healthy participants of both sexes in this study. The following instruments were used and evaluations performed: clinical evaluation, Mini-Mental State Exam, and quantitative sensory testing. Results: During the follow-up, there was reduction of mean corpuscular volume at each evaluation (p < 0.001) and significant increase in mean corpuscular hemoglobin concentration (p < 0.001). There was an increase of the olfactory (p < 0.001), salty (p = 0.024), sour (p = 0.020), bitter (p = 0.001), facial cold (p = 0.019), hand cold (p = 0.004), facial tactile (p < 0.001), hand tactile (p = 0.012) and facial vibration (p = 0.018) thresholds. Previous existing morbidities were associated with sensitivity changes in the individuals in this sample. Conclusion:This longitudinal study suggests that the loss of sensitivity with aging may be associated with the presence of morbidities in elders.
- Oral infections, comorbidities and sensory evidences in elderly: Cross-sectional study(2017) SILVA, Nathalia Santos Viana; SILVA, Luciana Alvarenga da; JALUUL, Omar; JACOB-FILHO, Wilson; SIQUEIRA, Silvia Regina Dowgan Tesseroli deBackground: Oral infections affect the general health and overlap with chronic diseases due to infectious-immune mechanisms. On the other side, sensory abnormalities may be symptoms of this association. Objective: To evaluate the prevalence of oral infections, comorbidities, health parameters and sensory abnormalities in elderly patients. Methods: Thirty (30) elderly with mean age 70.4 yo, distributed according to ages were evaluated with a protocol that included demographics, comorbidities, medications, laboratory tests, blood pressure, heart rate, minimental state examination, clinical oral evaluation and systematized sensory testing (gustative, olfactory, thermal, mechanical and pain thresholds). Data were tabled and statistically analyzed. Results: Twenty-three (76.6%) subjects had chronic diseases that increased according to the age. Seventeen (56.7%) elderly were having medication. Mean probing pocket depth was 1.90mm +/- 0.39 mm, mean clinical attachment level was 0.76mm +/- 0.54 mm and mean gingival bleeding index was 29.10% +/- 29.05%. All periodontal indexes increased with age (p < 0.05) and were associated with comorbidities and use of medication. Patients with chronic diseases had more numbness and pricking sensations (p = 0.031; p = 0.000). Main sensory findings were: abnormal gustative and vibratory thresholds, which were associated with hematological parameters (blood count, cholesterol levels and glycaemia). Periodontal parameters were associated with facial cold threshold (p = 0.000). Conclusion: This study showed an association between systemic diseases, periodontal indexes and sensory thresholds. Sensory findings were associated with blood parameters and are potential tools for periodical health evaluation. Inflammatory or neural mechanisms need further investigation.