BRUNO SERGIO FERREIRA MASSA
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
10 resultados
Resultados de Busca
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- MANAGEMENT OF INFANTILE BLOUNT'S DISEASE WITH MOLDED ORTHOSES: A NEW PERSPECTIVE (vol 24, pg 85, 2016)(2016) LUZO, Maria Candida de Miranda; MONTENEGRO, Nei Botter; MASSA, Bruno Sergio Ferreira; ANGELI, Luiz Renato Agrizzi de; CORDEIRO, Felippi Guizardi; GUARNIERO, Roberto
- MANAGEMENT OF INFANTILE BLOUNT'S DISEASE WITH MOLDED ORTHOSES: A NEW PERSPECTIVE(2016) MONTENEGRO, Nei Botter; MASSA, Bruno Sergio Ferreira; ANGELI, Luiz Renato Agrizzi deObjective: This retrospective study evaluated treatment with individually contoured molded bracing at early stages of the disease. Methods: We evaluated the medical records of patients undergoing treatment of Blount's disease with molded orthoses for medial decompression between 2010 and 2014. The deformity angle (Drennan's metaphyseal-diaphyseal angle) and Langenskiold classification were measured before and after treatment by a pediatric orthopedic surgeon with over 5 years of practice, blinded for the study and patients. Results: The mean age was 2.57 years old. Four patients were female and six male. Half of the total sample had bilateral disease. The average deformity angle showed a statistically significant reduction after treatment (p < 0.001). Gender and laterality did not statistically influence the change of the deformity angle after treatment (p>0.05). Conclusion: The nightly use of molded orthoses for medial decompression was effective in reducing the metaphyseal-diaphyseal angle in Blount's disease in children under 3 years of age, regardless of gender and bilateral disease. Patients over 3 years old did not benefit from bracing.
- MMP-1 promoter genotype and haplotype association with posterior tibial tendinopathy(2014) BARONEZA, Jose Eduardo; GODOY-SANTOS, Alexandre; MASSA, Bruno Ferreira; MUNHOZ, Francielle Bocon de Araujo; FERNANDES, Tulio Diniz; SANTOS, Maria Cristina Leme Godoy dosPurpose: Posterior tibial tendon (PIT) is particularly vulnerable and its insufficiency is recognized as the main cause of adult acquired flatfoot. Some patients have a predisposition without clinically recognized cause, suggesting that individual characteristics play an important role in tendinopathy. The objective of the present study is to investigate the association of -519 (rs1144393) matrix metalloproteinase-1 (MMP-1) polymorphism and the -1607 (rs1799750) and -519 MMP-1 haplotypes and risk of PTT dysfunction. Methods: The test group included 50 females who presented PTT dysfunction Grade 2 or 3, and who were submitted to surgical treatment, with histopathological examination of the tendon and magnetic resonance image (MRI) confirming tendinopathy, while the control group was 100 asymptomatic women who present intact MT at MRI. We analyzed functional polymorphisms MMP-1 and their haplotypes using polymerase chain reaction and restriction fragment length analysis. Results: There was a significant difference in the presence of the different alleles and genotypes between the control group and test group for the MMP-1 gene (p <= 0.01). The G allele of the -519 MMP-1 polymorphism increased susceptibility to degeneration in the PTT tendon and seems to be a genetic risk factor. Global haplotype analysis indicated a significant difference between both groups (p < 0.0001). Haplotypes G-2G and A-2G had statistically significant risk effect on PTT insufficiency. G-2G, p < 0.001; OR = 5.72 (CI, 2.84-11.52) and A-2G p = 0.002, OR = 3.95 (CI, 1.65-9.44). Conclusion: According to our results, -519 MMP-1 isolated and -1607/-519 MMP-1 haplotypes are associated to tendinopathy in posterior tibial tendon. (C) 2014 Published by Elsevier B.V.
- MODIFIED DEGA OSTEOTOMY IN TREATING DEVELOPMENTAL DYSPLASIA OF THE HIP (vol 26, pg 30, 2018)(2018) GUARNIERO, Roberto; SANCHEZ, Fernando Barbosa; MASSA, Bruno Sergio Ferreira; MONTENEGRO, Nei Botter; GRANGEIRO, Patricia Moreno; ANGELI, Luiz Renato Agrizzi De
- Congenital Clubfoot - Is the Ponseti Method the Definitive Solution?(2021) CORDEIRO, Felippi Guizardi; MACEDO, Rodrigo Sousa; MASSA, Bruno Sérgio Ferreira; GRANGEIRO, Patricia Moreno; GODOY-SANTOS, Alexandre Leme; FERNANDES, Túlio DinizAbstract Congenital clubfoot is one of the most common deformities at birth. The inadequacy or absence of treatment causes serious limitations for people with this condition. The initial treatment using the Ponseti method ensures functional results superior to other treatment modalities previously proposed. However, recurrences and neglected feet are still a challenge today. An understanding of the pathophysiology of the disease, as well as of the anatomy and local biomechanics and a thorough clinical and radiological evaluation of patients are essential to understanding the limits of the method and choosing the best treatment.
- REPRODUCIBILITY OF MODIFIED WALDENSTROM CLASSIFICATION IN PERTHES DISEASE(2021) CORDEIRO, Felippi Guizardi; GRANGEIRO, Patricia Moreno; MASSA, Bruno Sergio Ferreira; MONTENEGRO, Nei Botter; GUARNIERO, RobertoObjective: The purpose of our study is to evaluate intraobserver and interobserver reliability of modified Waldenstrom classification system for Legg-Calve-Perthes disease and assess the influence of the professional's area of expertise in the assessment. Methods: Twelve evaluators assessed 40 pairs of pelvic radiographs of patients with Legg-Calve-Perthes disease. After two weeks, a new evaluation was performed by the same evaluators. Kappa and Kendall's W indexes were used to evaluate both intraobserver and interobserver reliability and determine the influence of the evaluators' experience and area of expertise. Results: The average intraobserver kappa value was 0.394, with a reasonable agreement level. The interobserver Kappa value was 0.243 in the first evaluation (95% CI, 0.2270.259 and p < 0.0001) and 0.245 in the second evaluation (95% CI, 0.229-0.260 and p < 0.0001). The Kendall's W values obtained for pediatric orthopedists, radiologists and resident physicians were 0.686, 0.630 and 0.529 ( p < 0.0001), respectively. Conclusion: The modified Waldenstrom classification presented both moderate and reasonable levels of intraobserver agreement, and reasonable level of interobserver agreement. The evaluators' degree of experience and area of expertise influenced the concordance level found.
- Use of inlet radiographs in the assessment of reduction after the surgical treatment of developmental dysplasia of the hip(2017) MASSA, B. S. F.; GUARNIERO, R.; GODOY JR., R. M.; RODRIGUES, J. C.; MONTENEGRO, N. B.; CORDEIRO, F. G.Aims This pilot study aimed to evaluate prospectively the use of inlet radiographs of the hip as an alternative method of the assessment of reduction after the surgical treatment of developmental dysplasia of the hip (DDH). Patients and Methods The children in this study underwent surgery between January 2013 and January 2015. All had inlet radiographs and CT scans post-operatively. Data were analysed by determining inter-observer reliability and intra-observer reproducibility, using the kappa value (K). Differences were settled by discussion between the two observers until a consensus was reached. The sensitivity and specificity of the radiographic and CT results were compared. A total of 26 radiographs were obtained from 23 children, with a mean age of 2.38 years (one to five). Results Similar high levels of intra- and inter-observer agreement were observed (K = 0.834, 95% confidence interval (CI)). There was a high agreement between the radiographic and CT results (K = 0.834, 5% CI), with excellent sensitivity and a specificity of 95.5%. Conclusion These results suggest that inlet radiographs may be a reliable method of assessing the reduction of the hip after the surgical treatment of DDH.
- MODIFIED DEGA OSTEOTOMY IN TREATING DEVELOPMENTAL DYSPLASIA OF THE HIP(2018) GUARNIEIRO, Roberto; SANCHEZ, Fernando Barbosa; MASSA, Bruno Sergio Ferreira; MONTENEGRO, Nei Botter; GRANGEIRO, Patricia Moreno; ANGELI, Luiz Renato Agrizzi DeObjective: To retrospectively evaluate the preliminary postoperative results of modified Dega-type acetabular osteotomy to treat developmental dysplasia of the hip, confirming the efficacy and reproducibility of this technique. Methods: This retrospective study included patients older than 18 months. A total of 19 hips underwent modified Dega osteotomy. Results: Satisfactory results were obtained, with an average decrease of the acetabular index from 39.2 to 20.6 degrees. The final average center edge angle was 29.6 degrees. Hip joint congruence was reestablished in all cases, and as of this writing, only one case developed necrosis in the femoral head during follow-up. Conclusion: Modified Dega osteotomy demonstrated good initial results, as well as the potential for use in treating developmental dysplasia of the hip.
- A comparison study of radiographic and computerized tomographic angles in slipped capital femoral epiphysis(2017) DATTI, Ibere Pereira; MASSA, Bruno Sérgio Ferreira; EJNISMAN, Leandro; MONTENEGRO, Nei Botter; GUARNIERO, Roberto; KOJIMA, Kodi EdsonABSTRACT Objective: To compare proximal femur radiologic angles in patients with slipped capital femoral epiphysis and to analyze whether computerized tomography may modify the treatment. Methods: Cross-sectional study comparing and analyzing the similarity between angles and radiologic classification of interest in slipped capital femoral epiphysis (SCFE) . Results: It was observed that the therapeutic management in slipped capital femoral epiphysis might be modified depending on the classification and radiologic acquisition method adopted. Conclusion: Multiplanar assessment of proximal femoral deformity in patients with slipped capital femoral epiphysis is a viable option, with the potential to modify the disease classification and, consequently, the therapeutic management.
- RADIOLOGICAL RESULTS OF SEVERE SCFE TREATMENT AT IOT-FMUSP FROM 2012 TO 2018(2022) GABANA, Edelvan; MASSA, Bruno Sergio Ferreira; LUZO, Carlos Augusto Malheiros; REIS, Paulo Roberto Dos; SILVA, Jorge Dos Santos; KOJIMA, Kodi EdsonObjective: To assess the complications in patients with severe slipped capital femoral epiphysis treated with the Dunn or modified Dunn procedure from 2012 to 2018 at the Institute of Orthopedics and Traumatology, Medical School, Universidade de Sao Paulo. Methods: Analysis of medical records, preoperative and postoperative radiographs with at least one year of radiographic follow-up of patients with severe slipped capital femoral epiphysis. Results: We reviewed the complications in 19 operated cases from 2012 to 2018, out of which 36.8% had osteonecrosis of the femoral head, one patient had chondrolysis, and another had postoperative infection. Conclusion: The osteonecrosis rate observed in this series of cases is similar to that described in other orthopedic facilities. We assessed factors that could potentially influence this outcome, including other characteristics of the patient (obesity, endocrine diseases, and history of sports activities) and of the health system. Level of Evidence III, Restropective Case Series.