PEDRO HILTON DE ANDRADE FILHO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/08 - Laboratório de Anestesiologia, Hospital das Clínicas, Faculdade de Medicina
LIM/08 - Laboratório de Anestesiologia, Hospital das Clínicas, Faculdade de Medicina
2 resultados
Resultados de Busca
Agora exibindo 1 - 2 de 2
- Analgesic efficacy of erector spinae plane block versus paravertebral block in lung surgeries-A non-inferiority randomised controlled trial(2024) ANDRADE FILHO, Pedro Hilton de; PEREIRA, Victor Egypto; SOUSA, Daniel da Escossia Melo; COSTA, Ladyer da Gama; NUNES, Yuri Pinto; TAGLIALEGNA, Giovani; PAULA-GARCIA, Waynice Neiva de; SILVA, Joao ManoelBackground: Pain management plays an essential role in postoperative recovery after lung surgeries. The Erector Spinae Plane Block (ESPB) is a widely used regional anaesthesia technique; however, few clinical trials have compared this block to active control in thoracic surgeries. This study evaluated the non-inferiority of the analgesia provided by ESPB when compared to paravertebral block ( PVB) in lung surgeries. Methods: Randomised, active-controlled, blinded for patients and assessors, noninferiority trial. Patients who underwent unilateral lung surgeries were divided into two groups according to the regional anaesthesia technique-continuous ESPB or PVB at the T5 level. The primary outcome was to assess pain using a numerical rating scale (NRS) with a test of the interaction of three measures over 24 h postoperatively. An NRS score >= 7 was considered analgesia failure, and the prespecified non-inferiority margin was 10%. Results: In the interim analysis that terminated this study, 120 participants were enrolled. ESPB patients reported higher mean NRS general values over 24 h, 4.6 +/- 3.2 in the ESPB group versus 3.9 +/- 2.9 in the PVB group, with a difference of -0.67 (-15.2%) and 95%CI: -1.29 to -0.05 (p =.02), demonstrating not non-inferiority. In addition, the ESPB group presented higher NRS failure of analgesia over 24 h (p <.01) and required more postoperative opioids (p =.01 over 24 h). There was no difference in patient satisfaction between groups. Conclusion: This trial demonstrated that a continuous erector spinae plane block was not non-inferior to a continuous paravertebral block for analgesia after lung surgery but resulted in higher levels of postoperative pain and opioid consumption.
- Response to ""Is really a continuous erector spinae plane block inferior to a continuous paravertebral block for pain control following lung surgery?""(2024) ANDRADE FILHO, Pedro Hilton de; SILVA, Joao Manoel