JORGE MILHEM HADDAD
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina
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- A systematic review and meta-synthesis of qualitative studies on pelvic organ prolapse for the development of core outcome sets(2020) RADA, Maria Patricia; JONES, Stephanie; FALCONI, Gabriele; HADDAD, Jorge Milhem; BETSCHART, Cornelia; PERGIALIOTIS, Vasilios; DOUMOUCHTSIS, Stergios K.Aims In the current climate of evidence-based health care, the aim of this meta-synthesis was to collect and systematically analyse data from primary qualitative studies on pelvic organ prolapse (POP), to identify patient-centered perspectives on the natural course of POP. Information acquired in this study may be useful for ongoing research towards the development of core outcome sets (COS) in pelvic floor disorders. Methods A CHORUS Working Group performed a standardized search of three different databases (Medline, Embase, Scopus), from inception to October 2019. We selected qualitative studies on women's perspectives on POP that were published in the English language. Three reviewers independently evaluated the quality of eligible papers and highlighted recurrent themes based on patient perspectives. Results Eighteen qualitative studies including a total of 497 patients were assessed in this analysis. Our study revealed five superordinate themes, recurrently encountered in qualitative studies on POP: awareness of POP (6 studies), communication (9 studies), treatments (10 studies), effects on quality of life (6 studies), and self-image (3 studies). Five out of 10 quality criteria were met by all the studies included, based on an assessment performed using the critical appraisal skills program. Conclusions This is the first synthesis of qualitative studies that address POP-related experiences of women, highlighting five superordinate themes, of which treatment was the most commonly reported one. This synthesis' findings may guide quantitative research priorities and will hopefully contribute to the development of a COS for POP.
conferenceObject ANATOMICAL RELATIONSHIP BETWEEN DEVICES TVT-O AND ABREVO IN FRESH CADAVERS(2013) HADDAD, J. M.; FIORELLI, L. R.; FRANCO, V. F.; MATSUOKA, P.; CASENTINI, F.; BARACAT, E. C.conferenceObject A review of mobile voiding diary apps: Content and functionality features(2018) VACCARI, N.; SILVEIRA, L.; HADDAD, J.; BARACAT, E.; BERTOLINI, M. A.; FERREIRA, E.bookPart Incontinência urinária de esforço: diagnóstico(2016) ARAZAWA, Lilian Renata Fiorelli; LOCALI, Priscila Katsumi Matsuoka; HADDAD, Jorge Milhem- Validation of the Brazilian Portuguese version of the pelvic floor bother questionnaire(2019) PETERSON, Thais Villela; PINTO, Rodrigo Ambar; DAVILA, G. Willy; NAHAS, Sergio Carlos; BARACAT, Edmund Chada; HADDAD, Jorge MilhemIntroduction and hypothesisThe Pelvic Floor Bother Questionnaire (PFBQ) was designed to identify the presence and degree of bother associated with common pelvic floor symptoms. The PFBQ can be used in clinical practice and for research purposes, but it is not available in Brazilian Portuguese. We aimed to validate a cross-culturally adapted Brazilian Portuguese version of the PFBQ.MethodsA pilot-tested version of the PFBQ translated from English was evaluated with Brazilian patients suffering from pelvic floor disorders. Internal reliability, test-retest reliability, validity, and responsiveness to change were assessed.ResultsA total of 147 patients (mean age, 60.49years) were enrolled in the study. The Brazilian Portuguese version of the PFBQ demonstrated good reliability (=0.625; ICC=0.981). There was strong agreement beyond chance for each item (=0.895-1.00). The PFBQ correlated with stage of prolapse (p<0.01), number of urinary (=0.791, p<0.001) and fecal (=0.78, p<0.001) incontinence episodes, and obstructed defecation (=0.875, p<0.001).ConclusionsThe Brazilian Portuguese version of the PFBQ is a reliable, valid, and user-friendly instrument that can be used for assessing the presence and severity of pelvic floor symptoms in clinical and research settings in Brazil.
bookPart Cistite na mulher(2013) GUIDI, Homero Gustavo de Campos; HADDAD, Jorge MilhembookPart Prolapso uterino(2013) COLETTI, Silvia Helena; HADDAD, Jorge Milhem; RIBEIRO, Ricardo Muniz- Pelvic floor muscle function and quality of life in postmenopausal women with and without pelvic floor dysfunction(2018) FROTA, Isabella Parente Ribeiro; ROCHA, Adriana Bombonato Oliveira; VASCONCELOS NETO, Jose Ananias; VASCONCELOS, Camila Teixeira Moreira; MAGALHAES, Thais Fontes De; KARBAGE, Sara Arcanjo Lino; AUGUSTO, Kathiane Lustosa; NASCIMENTO, Simony Lira Do; HADDAD, Jorge Millem; BEZERRA, Leonardo Robson Pinheiro SobreiraIntroductionThis study aims to compare pelvic floor muscle (PFM) function in postmenopausal women with and without pelvic floor dysfunction (PFD) and the relation between PFM function and quality of life. Material and methodsA case-control study with 216 postmenopausal women with (n=126) and without (n=90) PFD. PFM function was assessed by digital vaginal palpation using the PERFECT scale. Specific quality of life was evaluated using the King's Health Questionnaire for women with urinary incontinence and the Prolapse Quality-of-Life Questionnaire for women with pelvic organ prolapse. We analyzed women with PFD into two categories: Oxford's grade 2 or 3 using a chi-squared test. ResultsOut of 126 womem with PFD 44 (34.9%) presented stress urinary incontinence, 21 (16.6%) had pelvic organ prolapse and 61 (48.4%) had urinary incontinence + pelvic organ prolapse. Strength had a median value 2 (0-5) in all women studied and most of them had insufficient strength, reduced endurance and repetition without statistical difference between groups. Incontinent women with strength 2 had worse perception of general health domain of King's Health Questionnaire (p=0.007). No association was found between PFM function and Prolapse Quality-of-Life Questionnaire. ConclusionsPFM function assessed by bidigital palpation in postmenopausal women was not sufficiently sensitive to differentiate between women with vs. women without PFM dysfunction and was not related with specific quality of life in women with urinary incontinence and pelvic organ prolapse, respectively. These data should be used to reinforce the widespread recommendation that PFM training is essencial in PFD treatment.
conferenceObject Transcutaneous tibial nerve electrical stimulation combined with transvaginal electrical stimulation in the treatment of overactive bladder syndrome: a blind randomized clinical trial(2018) GIARRETA, F.; HADDAD, J.; FUSCO, H.; BARACAT, E.; CASAROTTO, R.; FERREIRA, E.conferenceObject GENITAL PROLAPSE: RANDOMIZED, MULTICENTER TRIAL OF SURGICAL ASSESSMENT FOR FASCIAL REPAIR VERSUS SYNTHETIC POLYPROPYLENE MESH REPAIR(2012) SILVEIRA, S. B.; AUGE, A. P.; BELLA, Z. I. Jarmy-Di; NASTRI, F.; KAWABATA, M. G.; CARRAMAO, S.; RODRIGUES, C. A.; HADDAD, J. M.; BARACAT, E. C.