RODRIGO CERQUEIRA BORGES
Projetos de Pesquisa
Unidades Organizacionais
SVFOFITO-62, Hospital Universitário
LIM/51 - Laboratório de Emergências Clínicas, Hospital das Clínicas, Faculdade de Medicina
LIM/51 - Laboratório de Emergências Clínicas, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- Impact of Resistance Training in Chronic Obstructive Pulmonary Disease Patients During Periods of Acute Exacerbation(2014) BORGES, Rodrigo C.; CARVALHO, Celso R.Objective: To evaluate the effects of whole-body resistance training on exercise capacity, health-related quality of life (DROOL), and muscle strength in patients hospitalized for exacerbation of chronic obstructive pulmonary disease. Design: Randomized controlled trial. Setting: University hospital. Participants: Patients (N=46) were randomized to either a control group (CG) or training group (TG), and 29 patients completed the study. Intervention: Training consisted of weight-lifting exercises for 6 muscle groups in the upper and lower limbs (2 sets of 8 repetitions each), and the initial load was set at 80% of the 1-repetition maximum load. Main Outcome Measures: Patients were evaluated on the second day of hospitalization, at hospital discharge, and 30 days postdischarge. Patients were evaluated on the basis of the 6-minute walking distance (6MWD), DROOL, muscle strength, systemic inflammatory markers, and level of physical activity in daily life (PADL). Results: The CG showed a reduction in the strength of lower-limb muscles (P<.05) but not in the 6MWD (P>.05). In contrast, patients from the TG improved strength in the lower-limb muscles and 6MWD during and 30 days after hospitalization (P<.05). The TG also improved the impact domain in HRQOL after hospitalization. No improvement in PADL was observed in the TG. Finally, a reduction in the blood levels of inflammatory markers was observed only in the TO after hospitalization. Conclusions: Our results suggest that resistance training during hospitalization improves the 6MWD, DROOL, and lower-limb muscle strength, without altering the levels of systemic inflammation. However, future research should explore this intervention in larger randomized trials. (c) 2014 by the American Congress of Rehabilitation Medicine
- Physical Activity In Daily Life In Brazilian COPD Patients During and After Exacerbation(2012) BORGES, Rodrigo Cerqueira; CARVALHO, Celso Ricardo FernandesBackground: Although hospitalization is recognized as an important cause of reduction in physical activity in daily life (PADL) in COPD, there is only one study evaluating this effect, and it was performed in European COPD patients who have a lower PADL than that of South American COPD patients. Objectives: To investigate the effect of hospitalization due to acute exacerbation of PADL in Brazilian COPD patients and to evaluate the factors that determines the physical activity levels during hospitalization and after discharge. Methods: PADL was quantified using a 3-axis accelerometer on the 3rd day of hospitalization and 1 month after discharge in Brazilian COPD patients who were hospitalized due to disease exacerbation. Six-minute walking distance (6MWD), lower limb strength and pulmonary function were also evaluated. Results: A total of 20 patients completed the study. During hospitalization, patients spent most of the time (87%) lying down or sitting; however, 1 month after they were walking >40 min/day. In addition, patients with prior hospitalization had a lower level of physical activity compared to those without a previous history of hospitalization. The time spent walking during hospitalization was significantly explained by the quadriceps strength (r(2) = 0.29; p < 0.05), while 1 month after, the time spent walking was only significantly explained by the 6MWD (r(2) = 0.51; p = 0.02). Conclusions: Brazilian COPD patients are inactive during hospitalization but become active 1 month after discharge. Previously hospitalized are more inactive both during and after exacerbation. The quadriceps strength and 6MWD explain the physical activity levels during hospitalization and at home, respectively.
- Prevalence and Factors Associated with Sarcopenia in Hospitalized Elderly Patients(2022) BORGES, Rodrigo Cerqueira; CORREA, Daniel Imay; CORREA, Lourdes Jaqueline Sampaio; COLOMBO, Alexandra Siqueira; CARVALHO, Celso Ricardo FernandesBackground/Purpose: Sarcopenia is a public health problem; however, it remains poorly evaluated during hospitalization. The aim of this study was to evaluate the prevalence of sarcopenia and the factors associated with this condition in hospitalized elderly patients Methods: A total of 122 elderly individuals were evaluated in this case-control study (61=hospitalized and 61=non-hospitalized). Sarcopenia was defined and evaluated according to the criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). The Charlson comorbidity index, geriatric depression scale, body mass index (BMI), Barthel Index, Mini-Mental State Examination (MMSE), Lawton-Brody index, and Mini Nutritional Assessment Instrument-Short Form (MNA-SF) were also used for the evaluations. Results: The prevalence of sarcopenia was 38% in hospitalized patients compared to 11% in controls. Hospitalized elderly patients showed a significant reduction in functionality, muscle strength, and mental and nutritional status compared to the controls. Sarcopenic patients were older, had a lower BMI, and obtained worse MMSE results than non-sarcopenic individuals. There was an association between the MMSE results and the BMI in patients with sarcopenia that was independent of the group. Conclusion: Sarcopenia is highly prevalent in hospitalized elderly individuals, and it is associated with cognitive state and BMI.