MARIA KIYOKO OYAMADA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
54 resultados
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- Multimodal image analysis of the retina in Hunter syndrome (mucopolysaccharidosis type II): Case report(2018) SALVUCCI, Isadora Darriba Macedo; FINZI, Simone; OYAMADA, Maria Kiyoko; KIM, Chong Ae; PIMENTEL, Sergio Luis GianottiIntroduction: We report a case of retinal and posterior ocular findings in a 33-year-old man diagnosed with Hunter syndrome (Mucopolysaccharidosis type II) in a multimodal imaging way. Case presentation: Our patient was complaining of blurred night vision for the past 3 years. He had not received any systemic treatment for Hunter syndrome. Vision acuity was 20/20 in both eyes and corneas were clear. Fundus examination revealed bilateral crowded and hyperemic optic nerve heads (elevated in the ocular ultrasound) and areas of subretinal hypopigmentation. There was hyperautofluorescence at the central fovea and perifovea, and a diffuse bilateral choroidal fluorescence in angiography. Macular SD-OCT showed a thinning of the external retina at the perifovea in both eyes. Visual field testing showed a bilateral ring scotoma. The full field ERG was subnormal, with a negative response in the scotopic phase. Visual Evoked Potencial test and cranial MRI were normal. Conclusion: Our multimodal analysis reported here attempted to contribute to the knowledge of the natural history of GAG deposition in the eye, focusing on the retina and retinal pigment epithelium. Defining this natural history is essential for a proper comparison with Hunter patients receiving systemic treatment, thus determining if it can or cannot improve retinal function in humans with this disorder.
bookPart Paralisias de nervos oculomotores(2022) ASSIS, Rachel Oliveira de; OYAMADA, Maria Kiyokoarticle 9 Citação(ões) na Scopus Pattern-reversal electroretinograms for the diagnosis and management of disorders of the anterior visual pathway(2011) HOKAZONO, Kenzo; OYAMADA, Maria Kiyoko; MONTEIRO, Mario Luiz RibeiroThe pattern electroretinogram is an electrophysiological test that assesses the function of inner retinal layers, particularly the ganglion cells layer of retina, using a reversing checkerboard or grating pattern that produces no change in average luminance over time. The normal pattern electroretinogram is composed of a proeminent positive component (P50) and a large later negative component (N95). Since structural damage that compromises the retinal ganglion cell layer can lead to pattern electroretinogram changes, particularly in the N95 amplitude, the test can be useful in the treatment of a number of anterior visual pathway diseases. In this article, we review the methods for recording pattern electroretinogram and its usefulness in the diagnosis and management of diseases including inflammatory, hereditary, ischemic and compressive lesions of the anterior visual pathway.bookPart Doenças do Nervo Óptico(2016) MONTEIRO, Mário Luiz Ribeiro; CUNHA, Leonardo Provetti; KREUZ, André Carvalho; OYAMADA, Maria Kiyoko- Phacoemulsification and 1% atropine eye drops for treatment of antimetropic congenital microcoria associated with cataracts(2019) FERREIRA, Bruno Fortaleza de Aquino; SCHMIDT, Marina Brandao; BARBOSA, Leonardo Jose; OYAMADA, Maria Kiyoko; CARRICONDO, Pedro CarlosA rare case of bilateral congenital microcoria associated with antimetropia in a 47-year-old man is here described. The patient presented with a chief complaint of progressive vision loss in his right eye over the past five years. A slit-lamp examination and ultrasound biomicroscopy confirmed congenital microcoria and cataracts. Phacoemulsification was performed using an iris expansion device and the anterior capsule was stained using the ""trypan down under"" technique. Preoperative considerations, the surgical approach, and postoperative management are discussed.
conferenceObject New insights into structural and functional evaluation of the retina and optic nerve in Parkinson's disease(2023) MELLO, Luiz Marchesi; PARAGUAY, Isabela Bezerra; ANDRADE, Thais; ROCHA, Arthur do Nascimento; BARBOSA, Egberto; OYAMADA, Maria; MONTEIRO, Mario- Vogt-Koyanagi-Harada disease after discontinuation of systemic treatment(2022) SOUTO, Fernanda M. S.; LAVEZZO, Marcelo M.; OYAMADA, Maria K.; YAMAMOTO, Joyce H.
conferenceObject Comparative analysis of different treatment schedules in the course of Vogt-Koyanagi-Harada disease (VKHD)(2019) YAMAMOTO, Joyce H.; LAVEZZO, Marcelo Mendes; SAKATA, Viviane Mayumi; RODRIGUEZ, Ever Ernesto Caso; KANENOBU, Cintia; ABDALLAH, Smairah Frutuoso; MORITA, Celso; OYAMADA, Maria Kiyoko; HIRATA, Carlos EduardoconferenceObject Correlation between visual function and clinical/subclinical disease activity parameters in Vogt-Koyanagi-Harada disease (VKHD).(2017) LAVEZZO, Marcelo Mendes; SAKATA, Viviane Mayumi; RODRIGUEZ, Ever Ernesto Caso; ABDALLAH, Smairah Frutuoso; MORITA, Celso; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.conferenceObject Vogt-Koyanagi-Harada disease (VKHD) after systemic treatment discontinuation(2021) SOUTO, Fernanda Maria Silveira; MISSAKA, Ruy Felippe Brito Goncalves; LAVEZZO, Marcelo Mendes; NOBREGA, Priscilla Figueiredo Campos; SAKATA, Viviane Mayumi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.